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Links between DNA Replication, Stem Cells and Cancer

Genes, 2017-01, Vol.8 (2), p.45

2017

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Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

Nature communications, 2010-04, Vol.1 (1), p.9-9, Article 9

2010

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TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm

Genes & development, 2001-05, Vol.15 (10), p.1229-1241

2001

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Regulating the licensing of DNA replication origins in metazoa

Current opinion in cell biology, 2006-06, Vol.18 (3), p.231-239

2006

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Assembly of the Human Origin Recognition Complex Occurs through Independent Nuclear Localization of Its Components

The Journal of biological chemistry, 2011-07, Vol.286 (27), p.23831-23841

2011

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Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex

Nucleic acids research, 2009-01, Vol.37 (1), p.96-110

2009

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DNA damage activates p53 through a phosphorylation-acetylation cascade

Genes & development, 1998-09, Vol.12 (18), p.2831-2841

1998

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A Ca2+-dependent Mechanism of Neuronal Survival Mediated by the Microtubule-associated Protein p600

The Journal of biological chemistry, 2013-08, Vol.288 (34), p.24452-24464

2013

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The BAH domain facilitates the ability of human Orc1 protein to activate replication origins in vivo

The EMBO journal, 2006-11, Vol.25 (22), p.5372-5382

2006

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Overlapping but Distinct Patterns of Histone Acetylation by the Human Coactivators p300 and PCAF within Nucleosomal Substrates

The Journal of biological chemistry, 1999-01, Vol.274 (3), p.1189-1192

1999

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Role for Cdk1 (Cdc2)/Cyclin A in Preventing the Mammalian Origin Recognition Complex's Largest Subunit (Orc1) from Binding to Chromatin during Mitosis

Molecular and Cellular Biology, 2004-07, Vol.24 (13), p.5875-5886

2004

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p600, a Unique Protein Required for Membrane Morphogenesis and Cell Survival

Proceedings of the National Academy of Sciences - PNAS, 2005-10, Vol.102 (42), p.15093-15098

2005

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Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells

Cancer research (Chicago, Ill.), 2021-06, Vol.81 (11), p.2903-2917

2021

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Human Histone Deacetylase SIRT2 Interacts with the Homeobox Transcription Factor HOXA10

Journal of biochemistry (Tokyo), 2004-06, Vol.135 (6), p.695-700

2004

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Defective i6A37 modification of mitochondrial and cytosolic tRNAs results from pathogenic mutations in TRIT1 and its substrate tRNA

PLoS genetics, 2014-06, Vol.10 (6), p.e1004424-e1004424

2014

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An Exposed KID-Like Domain in Human T-Cell Lymphotropic Virus Type 1 Tax Is Responsible for the Recruitment of Coactivators CBP/p300

Molecular and Cellular Biology, 1998-09, Vol.18 (9), p.5052-5061

1998

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p300/CBP-associated Factor Histone Acetyltransferase Processing of a Peptide Substrate

The Journal of biological chemistry, 2000-07, Vol.275 (29), p.21953-21959

2000

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A family of PIKFYVE inhibitors with therapeutic potential against autophagy-dependent cancer cells disrupt multiple events in lysosome homeostasis

Autophagy, 2019-10, Vol.15 (10), p.1694-1718

2019

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p300 and p300/cAMP-responsive Element-binding Protein Associated Factor Interact with Human T-cell Lymphotropic Virus Type-1 Tax in a Multi-histone Acetyltransferase/Activator-Enhancer Complex

The Journal of biological chemistry, 2000-04, Vol.275 (16), p.11852-11857

2000

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Genetic Analysis of Human Orc2 Reveals Specific Domains That Are Required in Vivo for Assembly and Nuclear Localization of the Origin Recognition Complex

The Journal of biological chemistry, 2006-08, Vol.281 (32), p.23264-23273

2006

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Nonphosphorylated Human La Antigen Interacts with Nucleolin at Nucleolar Sites Involved in rRNA Biogenesis

Molecular and Cellular Biology, 2004-12, Vol.24 (24), p.10894-10904

2004

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ATP-dependent Nucleosome Remodeling and Histone Hyperacetylation Synergistically Facilitate Transcription of Chromatin

The Journal of biological chemistry, 2001-05, Vol.276 (18), p.14773-14783

2001

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Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

Nature communications, 2010-04, Vol.1 (1), p.1-12

2010

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Acetylation of Novel Sites in the Nucleosomal Binding Domain of Chromosomal Protein HMG-14 by p300 Alters Its Interaction with Nucleosomes

The Journal of biological chemistry, 2000-04, Vol.275 (15), p.11514-11520

2000

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Identification of genes that are essential to restrict genome duplication to once per cell division

Oncotarget, 2016-06, Vol.7 (23), p.34956-34976

2016

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Links between DNA Replication, Stem Cells and Cancer

Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm

Regulating the licensing of DNA replication origins in metazoa

Assembly of the Human Origin Recognition Complex Occurs through Independent Nuclear Localization of Its Components

Contributions of the two accessory subunits, RNASEH2B and RNASEH2C, to the activity and properties of the human RNase H2 complex

DNA damage activates p53 through a phosphorylation-acetylation cascade

A Ca2+-dependent Mechanism of Neuronal Survival Mediated by the Microtubule-associated Protein p600

The BAH domain facilitates the ability of human Orc1 protein to activate replication origins in vivo

Overlapping but Distinct Patterns of Histone Acetylation by the Human Coactivators p300 and PCAF within Nucleosomal Substrates

Role for Cdk1 (Cdc2)/Cyclin A in Preventing the Mammalian Origin Recognition Complex's Largest Subunit (Orc1) from Binding to Chromatin during Mitosis

p600, a Unique Protein Required for Membrane Morphogenesis and Cell Survival

Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells

Human Histone Deacetylase SIRT2 Interacts with the Homeobox Transcription Factor HOXA10

Defective i6A37 modification of mitochondrial and cytosolic tRNAs results from pathogenic mutations in TRIT1 and its substrate tRNA

An Exposed KID-Like Domain in Human T-Cell Lymphotropic Virus Type 1 Tax Is Responsible for the Recruitment of Coactivators CBP/p300

p300/CBP-associated Factor Histone Acetyltransferase Processing of a Peptide Substrate

A family of PIKFYVE inhibitors with therapeutic potential against autophagy-dependent cancer cells disrupt multiple events in lysosome homeostasis

p300 and p300/cAMP-responsive Element-binding Protein Associated Factor Interact with Human T-cell Lymphotropic Virus Type-1 Tax in a Multi-histone Acetyltransferase/Activator-Enhancer Complex

Genetic Analysis of Human Orc2 Reveals Specific Domains That Are Required in Vivo for Assembly and Nuclear Localization of the Origin Recognition Complex

Nonphosphorylated Human La Antigen Interacts with Nucleolin at Nucleolar Sites Involved in rRNA Biogenesis

ATP-dependent Nucleosome Remodeling and Histone Hyperacetylation Synergistically Facilitate Transcription of Chromatin

Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors

Acetylation of Novel Sites in the Nucleosomal Binding Domain of Chromosomal Protein HMG-14 by p300 Alters Its Interaction with Nucleosomes

Identification of genes that are essential to restrict genome duplication to once per cell division

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