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Mechanism of Quinolone Action and Resistance

Biochemistry (Easton), 2014-03, Vol.53 (10), p.1565-1574

2014

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Fluoroquinolone interactions with Mycobacterium tuberculosis gyrase: Enhancing drug activity against wild-type and resistant gyrase

Proceedings of the National Academy of Sciences - PNAS, 2016-02, Vol.113 (7), p.E839-E846

2016

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Topoisomerase IV-quinolone interactions are mediated through a water-metal ion bridge: mechanistic basis of quinolone resistance

Nucleic acids research, 2013-04, Vol.41 (8), p.4628

2013

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Role of the Water-Metal Ion Bridge in Quinolone Interactions with Escherichia coli Gyrase

International journal of molecular sciences, 2023-02, Vol.24 (3), p.2879

2023

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Overcoming Target-Mediated Quinolone Resistance in Topoisomerase IV by Introducing Metal-Ion-Independent Drug–Enzyme Interactions

ACS chemical biology, 2013-12, Vol.8 (12), p.2660-2668

2013

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A RADAR-Based Assay to Isolate Covalent DNA Complexes in Bacteria

Antibiotics (Basel), 2019-02, Vol.8 (1), p.17

2019

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Drug Interactions with Bacillus anthracis Topoisomerase IV: Biochemical Basis for Quinolone Action and Resistance

Biochemistry (Easton), 2012-01, Vol.51 (1), p.370-381

2012

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Role of the Water–Metal Ion Bridge in Mediating Interactions between Quinolones and Escherichia coli Topoisomerase IV

Biochemistry (Easton), 2014-09, Vol.53 (34), p.5558-5567

2014

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Activity of Quinolone CP-115,955 Against Bacterial and Human Type II Topoisomerases Is Mediated by Different Interactions

Biochemistry (Easton), 2015-02, Vol.54 (5), p.1278-1286

2015

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Bacillus anthracis GrlAV96A topoisomerase IV, a quinolone resistance mutation that does not affect the water-metal ion bridge

Antimicrobial agents and chemotherapy, 2014-12, Vol.58 (12), p.7182-7187

2014

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Mitochondrial genome sequence of Unionicola foili (Acari: Unionicolidae): a unique gene order with implications for phylogenetic inference

Experimental & applied acarology, 2009-12, Vol.49 (4), p.305-316

2009

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Bacillus anthracis GrlA V96A Topoisomerase IV, a Quinolone Resistance Mutation That Does Not Affect the Water-Metal Ion Bridge

Antimicrobial agents and chemotherapy, 2014-12, Vol.58 (12), p.7182-7187

2014

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Gyrase and Topoisomerase IV as Targets for Antibacterial Drugs

Molecular Life Sciences, p.489-493

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Identification and validation of a novel pathogenic variant in GDF2 (BMP9) responsible for hereditary hemorrhagic telangiectasia and pulmonary arteriovenous malformations

American journal of medical genetics. Part A, 2022-03, Vol.188 (3), p.959-964

2022

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Integrative Multiomics to Dissect the Lung Transcriptional Landscape of Pulmonary Arterial Hypertension

Journal of vascular surgery cases and innovative techniques, 2023-01, Vol.9 (2)

2023

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Identification and validation of a novel pathogenic variant in GDF2 (BMP9) responsible for hereditary hemorrhagic telangiectasia and pulmonary arteriovenous malformations

American journal of medical genetics. Part A, 2022, Vol.188 (3), p.959-964

2022

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Mechanism of Quinolone Action and Resistance

Fluoroquinolone interactions with Mycobacterium tuberculosis gyrase: Enhancing drug activity against wild-type and resistant gyrase

Topoisomerase IV-quinolone interactions are mediated through a water-metal ion bridge: mechanistic basis of quinolone resistance

Role of the Water-Metal Ion Bridge in Quinolone Interactions with Escherichia coli Gyrase

Overcoming Target-Mediated Quinolone Resistance in Topoisomerase IV by Introducing Metal-Ion-Independent Drug–Enzyme Interactions

A RADAR-Based Assay to Isolate Covalent DNA Complexes in Bacteria

Drug Interactions with Bacillus anthracis Topoisomerase IV: Biochemical Basis for Quinolone Action and Resistance

Role of the Water–Metal Ion Bridge in Mediating Interactions between Quinolones and Escherichia coli Topoisomerase IV

Activity of Quinolone CP-115,955 Against Bacterial and Human Type II Topoisomerases Is Mediated by Different Interactions

Bacillus anthracis GrlAV96A topoisomerase IV, a quinolone resistance mutation that does not affect the water-metal ion bridge

Mitochondrial genome sequence of Unionicola foili (Acari: Unionicolidae): a unique gene order with implications for phylogenetic inference

Bacillus anthracis GrlA V96A Topoisomerase IV, a Quinolone Resistance Mutation That Does Not Affect the Water-Metal Ion Bridge

Gyrase and Topoisomerase IV as Targets for Antibacterial Drugs

Identification and validation of a novel pathogenic variant in GDF2 (BMP9) responsible for hereditary hemorrhagic telangiectasia and pulmonary arteriovenous malformations

Integrative Multiomics to Dissect the Lung Transcriptional Landscape of Pulmonary Arterial Hypertension

Identification and validation of a novel pathogenic variant in GDF2 (BMP9) responsible for hereditary hemorrhagic telangiectasia and pulmonary arteriovenous malformations

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