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EP4 Antagonism by E7046 diminishes Myeloid immunosuppression and synergizes with Treg-reducing IL-2-Diphtheria toxin fusion protein in restoring anti-tumor immunity

Oncoimmunology, 2017-08, Vol.6 (8), p.e1338239-e1338239

2017

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A bispecific anti-PD-1 and PD-L1 antibody induces PD-1 cleavage and provides enhanced anti-tumor activity

Oncoimmunology, 2024, Vol.13 (1), p.2316945-2316945

2024

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BCL11B is required for positive selection and survival of double-positive thymocytes

The Journal of experimental medicine, 2007-11, Vol.204 (12), p.3003-3015

2007

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Transcription factor Bcl11b controls selection of invariant natural killer T-cells by regulating glycolipid presentation in double-positive thymocytes

Proceedings of the National Academy of Sciences - PNAS, 2011-04, Vol.108 (15), p.6211-6216

2011

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Critical role of Bcl11b in suppressor function of T regulatory cells and prevention of inflammatory bowel disease

The Journal of experimental medicine, 2011-09, Vol.208 (10), p.2069-2081

2011

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BCL11B participates in the activation of IL2 gene expression in CD4+ T lymphocytes

Blood, 2006-10, Vol.108 (8), p.2695-2702

2006

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Antigen-specific clonal expansion and cytolytic effector function of CD8+ T lymphocytes depend on the transcription factor Bcl11b

The Journal of experimental medicine, 2010-08, Vol.207 (8), p.1687-1699

2010

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Flow cytometry analysis of transcription factors in T lymphocytes

Methods in molecular biology (Clifton, N.J.), 2010, Vol.647, p.377

2010

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Abstract 3431: Dose range finding study in non-human primates confirms the unique mechanism of action of CTX-8371, a novel bispecific antibody blocking PD-1 and PD-L1

Cancer research (Chicago, Ill.), 2022-06, Vol.82 (12_Supplement), p.3431-3431

2022

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Intranasal Vaccination Using Interleukin-12 and Cholera Toxin Subunit B as Adjuvants To Enhance Mucosal and Systemic Immunity to Human Immunodeficiency Virus Type 1 Glycoproteins

Journal of Virology, 2003-05, Vol.77 (10), p.5589-5597

2003

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Abstract 5522: Evaluation of eribulin-induced alterations of the intact immune cell landscape in spleens and tumors from tumor-bearing immunocompetent mice

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.5522-5522

2020

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Bispecific anti-PD-1/PD-L1 antibody CTX-8371 to promote cellular clustering and PD-1 shedding, antitumor activity and tolerability

Journal of clinical oncology, 2021-05, Vol.39 (15_suppl), p.e15056-e15056

2021

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Abstract 4586: Intratumoral Treg cell depletion by local administration of IL-2-Diphteria toxin fusion protein E7777 induces a therapeutic and memory anti-tumor immune response in preclinical models

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.4586-4586

2017

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Abstract 4607: Specific inhibition of PGE2-EP4 signaling by E7046 promotes anti-tumor activity of checkpoint blockade agents through boosting cytotoxic T cell activity

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.4607-4607

2017

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Abstract 1227: Macrophage depletion enhances the anticancer efficacy of eribulin mesylate in mice bearing syngeneic tumors

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.1227-1227

2013

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Abstract 3269: Discovery and characterization of E7766, a novel macrocycle-bridged STING agonist with pan-genotypic and potent antitumor activity through intravesical and intratumoral administration

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.3269-3269

2019

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Abstract B198: Pharmacological profile of the PGE2 EP4 receptor antagonist E7046

Molecular cancer therapeutics, 2015-12, Vol.14 (12_Supplement_2), p.B198-B198

2015

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Abstract 275: ER-886046, an antagonist of PGE2 receptor type-4, induces an effective antitumor immune response in mice by attenuating intratumoral MDSCs and TAMs

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.275-275

2015

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Abstract B90: Eribulin mesylate alters immune homeostasis in mice bearing syngeneic tumors

Cancer research (Chicago, Ill.), 2013-01, Vol.73 (1_Supplement), p.B90-B90

2013

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Abstract B034: Preclinical immune antitumor activity of myeloid-targeting E7046 and Treg depleting E7777

Cancer immunology research, 2016-01, Vol.4 (1_Supplement), p.B034-B034

2016

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Energy effect of on-node processing of ECG signals

2010 Digest of Technical Papers International Conference on Consumer Electronics (ICCE), 2010, p.7-8

2010

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TYPES OF WAITING IN MATEI VIȘNIEC’ S DRAMATURGY

Journal of Romanian Literay Studies, 2020 (20), p.1328-1333

Albu, Andreea-Diana

2020

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THE IMAGE OF WAR IN MATEI VISNIEC’ S DRAMATURGY

Journal of Romanian Literay Studies, 2020 (23), p.962-966

Albu, Andreea-Diana

2020

Volltextzugriff (PDF)

WAITING FOR DEATH IN MATEI VIȘNIEC’ S DRAMATURGY

Journal of Romanian Literay Studies, 2020 (21), p.1109-1113

Albu, Andreea-Diana

2020

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IL-12 as a mucosal adjuvant for enhancement of HIV-1 and influenza virus immune responses

Albu, Diana Iulia

2004

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EP4 Antagonism by E7046 diminishes Myeloid immunosuppression and synergizes with Treg-reducing IL-2-Diphtheria toxin fusion protein in restoring anti-tumor immunity

A bispecific anti-PD-1 and PD-L1 antibody induces PD-1 cleavage and provides enhanced anti-tumor activity

BCL11B is required for positive selection and survival of double-positive thymocytes

Transcription factor Bcl11b controls selection of invariant natural killer T-cells by regulating glycolipid presentation in double-positive thymocytes

Critical role of Bcl11b in suppressor function of T regulatory cells and prevention of inflammatory bowel disease

BCL11B participates in the activation of IL2 gene expression in CD4+ T lymphocytes

Antigen-specific clonal expansion and cytolytic effector function of CD8+ T lymphocytes depend on the transcription factor Bcl11b

Flow cytometry analysis of transcription factors in T lymphocytes

Abstract 3431: Dose range finding study in non-human primates confirms the unique mechanism of action of CTX-8371, a novel bispecific antibody blocking PD-1 and PD-L1

Intranasal Vaccination Using Interleukin-12 and Cholera Toxin Subunit B as Adjuvants To Enhance Mucosal and Systemic Immunity to Human Immunodeficiency Virus Type 1 Glycoproteins

Abstract 5522: Evaluation of eribulin-induced alterations of the intact immune cell landscape in spleens and tumors from tumor-bearing immunocompetent mice

Bispecific anti-PD-1/PD-L1 antibody CTX-8371 to promote cellular clustering and PD-1 shedding, antitumor activity and tolerability

Abstract 4586: Intratumoral Treg cell depletion by local administration of IL-2-Diphteria toxin fusion protein E7777 induces a therapeutic and memory anti-tumor immune response in preclinical models

Abstract 4607: Specific inhibition of PGE2-EP4 signaling by E7046 promotes anti-tumor activity of checkpoint blockade agents through boosting cytotoxic T cell activity

Abstract 1227: Macrophage depletion enhances the anticancer efficacy of eribulin mesylate in mice bearing syngeneic tumors

Abstract 3269: Discovery and characterization of E7766, a novel macrocycle-bridged STING agonist with pan-genotypic and potent antitumor activity through intravesical and intratumoral administration

Abstract B198: Pharmacological profile of the PGE2 EP4 receptor antagonist E7046

Abstract 275: ER-886046, an antagonist of PGE2 receptor type-4, induces an effective antitumor immune response in mice by attenuating intratumoral MDSCs and TAMs

Abstract B90: Eribulin mesylate alters immune homeostasis in mice bearing syngeneic tumors

Abstract B034: Preclinical immune antitumor activity of myeloid-targeting E7046 and Treg depleting E7777

Energy effect of on-node processing of ECG signals

TYPES OF WAITING IN MATEI VIȘNIEC’ S DRAMATURGY

THE IMAGE OF WAR IN MATEI VISNIEC’ S DRAMATURGY

WAITING FOR DEATH IN MATEI VIȘNIEC’ S DRAMATURGY

IL-12 as a mucosal adjuvant for enhancement of HIV-1 and influenza virus immune responses

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