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Recent advances in, and challenges of, designing OMA1 drug screens

Pharmacological research, 2022-02, Vol.176, p.106063-106063, Article 106063

Alavi, Marcel V.

2022

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Dominant optic atrophy, OPA1, and mitochondrial quality control: understanding mitochondrial network dynamics

Molecular neurodegeneration, 2013-09, Vol.8 (1), p.32-32

2013

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Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload

Cardiovascular research, 2012-06, Vol.94 (3), p.408-417

2012

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Targeted OMA1 therapies for cancer

International journal of cancer, 2019-11, Vol.145 (9), p.2330-2341

Alavi, Marcel V.

2019

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OMA1—An integral membrane protease?

Biochimica et biophysica acta. Proteins and proteomics, 2021-02, Vol.1869 (2), p.140558-140558, Article 140558

Alavi, Marcel V.

2021

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Tau phosphorylation and OPA1 proteolysis are unrelated events: Implications for Alzheimer's Disease

Biochimica et biophysica acta. Molecular cell research, 2021-11, Vol.1868 (12), p.119116-119116, Article 119116

Alavi, Marcel V.

2021

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Col4a1 mutations cause progressive retinal neovascular defects and retinopathy

Scientific reports, 2016-01, Vol.6 (1), p.18602-18602, Article 18602

2016

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OMA1 High-Throughput Screen Reveals Protease Activation by Kinase Inhibitors

ACS chemical biology, 2021-11, Vol.16 (11), p.2202-2211

Alavi, Marcel V

2021

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Aging and Vision

Advances in experimental medicine and biology, 2016-01, Vol.854, p.393-399

2016

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Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis

Science translational medicine, 2017-04, Vol.9 (385)

2017

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Type IV Collagens and Basement Membrane Diseases: Cell Biology and Pathogenic Mechanisms

Current topics in membranes, 2015, Vol.76, p.61-116

2015

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Electrophysiological and Histologic Assessment of Retinal Ganglion Cell Fate in a Mouse Model for OPA1-Associated Autosomal Dominant Optic Atrophy

Investigative ophthalmology & visual science, 2010-03, Vol.51 (3), p.1424-1431

2010

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A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy

Brain (London, England : 1878), 2007-04, Vol.130 (4), p.1029-1042

2007

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Solving a 50 year mystery of a missing OPA1 mutation: more insights from the first family diagnosed with autosomal dominant optic atrophy

Molecular neurodegeneration, 2010-06, Vol.5 (1), p.25-25, Article 25

2010

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Long-term photoreceptor rescue in two rodent models of retinitis pigmentosa by adeno-associated virus delivery of Stanniocalcin-1

Experimental eye research, 2017-12, Vol.165, p.175-181

2017

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Strain-Dependent Anterior Segment Dysgenesis and Progression to Glaucoma in Col4a1 Mutant Mice

Investigative ophthalmology & visual science, 2015-10, Vol.56 (11), p.6823-6831

2015

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In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter Mouse

Investigative ophthalmology & visual science, 2015-10, Vol.56 (11), p.6961-6970

2015

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Subtle neurological and metabolic abnormalities in an Opa1 mouse model of autosomal dominant optic atrophy

Experimental neurology, 2009-12, Vol.220 (2), p.404-409

2009

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A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16

Human molecular genetics, 2011-05, Vol.20 (10), p.1893-1905

2011

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Identification of genes that are linked with optineurin expression using a combined RNAi–microarray approach

Experimental eye research, 2007-10, Vol.85 (4), p.450-461

2007

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In vivo longitudinal assessment of cellular processes using fluorescence reporters

Mitochondrion, 2015-09, Vol.24, p.S22-S23

2015

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Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload: OPA1 deficit and cardiac mitochondria

Cardiovascular research, 2012-06, Vol.94 (3), p.408-17

2012

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A splice site mutation in the murine Opal gene features pathology of autosomal dominant optic atrophy

Brain (London, England : 1878), 2007, Vol.130, p.1029-1042

2007

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Mycobacterial Disease and Impaired IFN-γ Immunity in Humans with Inherited ISG15 Deficiency

Science (American Association for the Advancement of Science), 2012-09, Vol.337 (6102), p.1684-1688

2012

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Recent advances in, and challenges of, designing OMA1 drug screens

Dominant optic atrophy, OPA1, and mitochondrial quality control: understanding mitochondrial network dynamics

Allosteric Inhibition of the IRE1α RNase Preserves Cell Viability and Function during Endoplasmic Reticulum Stress

Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload

Targeted OMA1 therapies for cancer

OMA1—An integral membrane protease?

Tau phosphorylation and OPA1 proteolysis are unrelated events: Implications for Alzheimer's Disease

Col4a1 mutations cause progressive retinal neovascular defects and retinopathy

OMA1 High-Throughput Screen Reveals Protease Activation by Kinase Inhibitors

Aging and Vision

Individuals with progranulin haploinsufficiency exhibit features of neuronal ceroid lipofuscinosis

Type IV Collagens and Basement Membrane Diseases: Cell Biology and Pathogenic Mechanisms

Electrophysiological and Histologic Assessment of Retinal Ganglion Cell Fate in a Mouse Model for OPA1-Associated Autosomal Dominant Optic Atrophy

A splice site mutation in the murine Opa1 gene features pathology of autosomal dominant optic atrophy

Solving a 50 year mystery of a missing OPA1 mutation: more insights from the first family diagnosed with autosomal dominant optic atrophy

Long-term photoreceptor rescue in two rodent models of retinitis pigmentosa by adeno-associated virus delivery of Stanniocalcin-1

Strain-Dependent Anterior Segment Dysgenesis and Progression to Glaucoma in Col4a1 Mutant Mice

In Vivo Visualization of Endoplasmic Reticulum Stress in the Retina Using the ERAI Reporter Mouse

Subtle neurological and metabolic abnormalities in an Opa1 mouse model of autosomal dominant optic atrophy

A clinically complex form of dominant optic atrophy (OPA8) maps on chromosome 16

Identification of genes that are linked with optineurin expression using a combined RNAi–microarray approach

In vivo longitudinal assessment of cellular processes using fluorescence reporters

Down-regulation of OPA1 alters mouse mitochondrial morphology, PTP function, and cardiac adaptation to pressure overload: OPA1 deficit and cardiac mitochondria

A splice site mutation in the murine Opal gene features pathology of autosomal dominant optic atrophy

Mycobacterial Disease and Impaired IFN-γ Immunity in Humans with Inherited ISG15 Deficiency

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