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Pluronic ® block copolymers for overcoming drug resistance in cancer

Advanced drug delivery reviews, 2002-09, Vol.54 (5), p.759-779

2002

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Differential metabolic responses to pluronic in MDR and non-MDR cells: a novel pathway for chemosensitization of drug resistant cancers

Journal of controlled release, 2010-02, Vol.142 (1), p.89-100

2010

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Effects of pluronic and doxorubicin on drug uptake, cellular metabolism, apoptosis and tumor inhibition in animal models of MDR cancers

Journal of controlled release, 2010-05, Vol.143 (3), p.290-301

2010

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Effects of Pluronic block copolymers on drug absorption in Caco-2 cell monolayers

Pharmaceutical research, 1998-06, Vol.15 (6), p.850-855

1998

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ICAM‐1 isoforms: specific activity and sensitivity to cleavage by leukocyte elastase and cathepsin G

European journal of immunology, 2003-05, Vol.33 (5), p.1351-1360

2003

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Pluronic block copolymers in drug delivery: from micellar nanocontainers to biological response modifiers

Critical reviews in therapeutic drug carrier systems, 2002, Vol.19 (1), p.1-72

2002

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Optimal structure requirements for pluronic block copolymers in modifying P-glycoprotein drug efflux transporter activity in bovine brain microvessel endothelial cells

The Journal of pharmacology and experimental therapeutics, 2003-02, Vol.304 (2), p.845-854

2003

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Effect of pluronic P85 on ATPase activity of drug efflux transporters

Pharmaceutical research, 2004-12, Vol.21 (12), p.2226-2233

2004

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Pluronic block copolymers alter apoptotic signal transduction of doxorubicin in drug-resistant cancer cells

Journal of controlled release, 2005-07, Vol.105 (3), p.269-278

2005

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Mechanism of pluronic effect on P-glycoprotein efflux system in blood-brain barrier: contributions of energy depletion and membrane fluidization

The Journal of pharmacology and experimental therapeutics, 2001-11, Vol.299 (2), p.483

2001

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An essential relationship between ATP depletion and chemosensitizing activity of Pluronic ® block copolymers

Journal of controlled release, 2003-08, Vol.91 (1), p.75-83

2003

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Transcriptional Activation of Gene Expression by Pluronic Block Copolymers in Stably and Transiently Transfected Cells

Molecular therapy, 2006-04, Vol.13 (4), p.804-813

2006

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Distribution kinetics of a micelle-forming block copolymer Pluronic P85

Journal of controlled release, 2004-12, Vol.100 (3), p.389-397

2004

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Sensitization of cells overexpressing multidrug-resistant proteins by pluronic P85

Pharmaceutical research, 2003-10, Vol.20 (10), p.1581-1590

2003

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Pluronic P85 enhances the delivery of digoxin to the brain: in vitro and in vivo studies

The Journal of pharmacology and experimental therapeutics, 2001-02, Vol.296 (2), p.551

2001

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Micelle Formation and Solubilization of Fluorescent Probes in Poly(oxyethylene-b-oxypropylene-b-oxyethylene) Solutions

Macromolecules, 1995-03, Vol.28 (7), p.2303-2314

1995

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Water-Soluble Block Polycations as Carriers for Oligonucleotide Delivery

Bioconjugate chemistry, 1995-11, Vol.6 (6), p.639-643

1995

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Block copolymeric biotransport carriers as versatile vehicles for drug delivery

Expert opinion on investigational drugs, 1998-09, Vol.7 (9), p.1453-1473

1998

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Effects of pluronic P85 on GLUT1 and MCT1 transporters in the blood-brain barrier

Pharmaceutical research, 2004-11, Vol.21 (11), p.1993-2000

2004

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Pluronic ® block copolymers as novel polymer therapeutics for drug and gene delivery

Journal of Controlled Release, 2002-08, Vol.82 (2), p.189-212

2002

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A new class of drug carriers: micelles of poly(oxyethylene)-poly(oxypropylene) block copolymers as microcontainers for drug targeting from blood in brain

Journal of controlled release, 1992-10, Vol.22 (2), p.141-157

1992

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Prevention of MDR development in leukemia cells by micelle-forming polymeric surfactant

Journal of controlled release, 2008-11, Vol.131 (3), p.220-227

2008

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The effect of the nonionic block copolymer pluronic P85 on gene expression in mouse muscle and antigen-presenting cells

Biomaterials, 2009-02, Vol.30 (6), p.1232-1245

2009

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Self-assembling Pluronic®-modified polycations in gene delivery

Current opinion in colloid & interface science, 2006-10, Vol.11 (4), p.217-223

2006

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Alteration of Genomic Responses to Doxorubicin and Prevention of MDR in Breast Cancer Cells by a Polymer Excipient: Pluronic P85

Molecular pharmaceutics, 2006-03, Vol.3 (2), p.113-123

2006

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Pluronic ® block copolymers for overcoming drug resistance in cancer

Differential metabolic responses to pluronic in MDR and non-MDR cells: a novel pathway for chemosensitization of drug resistant cancers

Effects of pluronic and doxorubicin on drug uptake, cellular metabolism, apoptosis and tumor inhibition in animal models of MDR cancers

Effects of Pluronic block copolymers on drug absorption in Caco-2 cell monolayers

ICAM‐1 isoforms: specific activity and sensitivity to cleavage by leukocyte elastase and cathepsin G

Pluronic block copolymers in drug delivery: from micellar nanocontainers to biological response modifiers

Optimal structure requirements for pluronic block copolymers in modifying P-glycoprotein drug efflux transporter activity in bovine brain microvessel endothelial cells

Effect of pluronic P85 on ATPase activity of drug efflux transporters

Pluronic block copolymers alter apoptotic signal transduction of doxorubicin in drug-resistant cancer cells

Mechanism of pluronic effect on P-glycoprotein efflux system in blood-brain barrier: contributions of energy depletion and membrane fluidization

An essential relationship between ATP depletion and chemosensitizing activity of Pluronic ® block copolymers

Transcriptional Activation of Gene Expression by Pluronic Block Copolymers in Stably and Transiently Transfected Cells

Distribution kinetics of a micelle-forming block copolymer Pluronic P85

Sensitization of cells overexpressing multidrug-resistant proteins by pluronic P85

Pluronic P85 enhances the delivery of digoxin to the brain: in vitro and in vivo studies

Micelle Formation and Solubilization of Fluorescent Probes in Poly(oxyethylene-b-oxypropylene-b-oxyethylene) Solutions

Water-Soluble Block Polycations as Carriers for Oligonucleotide Delivery

Block copolymeric biotransport carriers as versatile vehicles for drug delivery

Effects of pluronic P85 on GLUT1 and MCT1 transporters in the blood-brain barrier

Pluronic ® block copolymers as novel polymer therapeutics for drug and gene delivery

A new class of drug carriers: micelles of poly(oxyethylene)-poly(oxypropylene) block copolymers as microcontainers for drug targeting from blood in brain

Prevention of MDR development in leukemia cells by micelle-forming polymeric surfactant

The effect of the nonionic block copolymer pluronic P85 on gene expression in mouse muscle and antigen-presenting cells

Self-assembling Pluronic®-modified polycations in gene delivery

Alteration of Genomic Responses to Doxorubicin and Prevention of MDR in Breast Cancer Cells by a Polymer Excipient: Pluronic P85

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