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Results From a First‐in‐Human Study of BNZ‐1, a Selective Multicytokine Inhibitor Targeting Members of the Common Gamma (γc) Family of Cytokines

Journal of clinical pharmacology, 2020-02, Vol.60 (2), p.264-273

2020

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A quantitative high-resolution genetic profile rapidly identifies sequence determinants of hepatitis C viral fitness and drug sensitivity

PLoS pathogens, 2014-04, Vol.10 (4), p.e1004064

2014

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HIV-1 integrase inhibitors: 2005-2006 update

Medicinal research reviews, 2008-01, Vol.28 (1), p.118-154

2008

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Functional Constraint Profiling of a Viral Protein Reveals Discordance of Evolutionary Conservation and Functionality

PLoS genetics, 2015-07, Vol.11 (7), p.e1005310-e1005310

2015

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Allosteric Inhibitor Development Targeting HIV-1 Integrase

ChemMedChem, 2011-02, Vol.6 (2), p.228-241

2011

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High-throughput profiling of influenza A virus hemagglutinin gene at single-nucleotide resolution

Scientific reports, 2014-05, Vol.4 (1), p.4942, Article 4942

2014

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Blocking interactions between HIV-1 integrase and cellular cofactors: an emerging anti-retroviral strategy

Trends in pharmacological sciences (Regular ed.), 2007-10, Vol.28 (10), p.526-535

2007

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Systematic Identification of H274Y Compensatory Mutations in Influenza A Virus Neuraminidase by High-Throughput Screening

Journal of Virology, 2013-01, Vol.87 (2), p.1193-1199

2013

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HIV-1 quasispecies delineation by tag linkage deep sequencing

PloS one, 2014-05, Vol.9 (5), p.e97505-e97505

2014

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High-throughput profiling of point mutations across the HIV-1 genome

Retrovirology, 2014-12, Vol.11 (1), p.124-124, Article 124

2014

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Single-Round, Multiplexed Antibody Mimetic Design through mRNA Display

Angewandte Chemie International Edition, 2012-12, Vol.51 (50), p.12449-12453

International ed. in English, 2012

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Correction: Functional Constraint Profiling of a Viral Protein Reveals Discordance of Evolutionary Conservation and Functionality

PLoS genetics, 2017-04, Vol.13 (4), p.e1006709-e1006709

2017

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A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication

PloS one, 2012-09, Vol.7 (9), p.e45177

2012

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Discovery of a Small-Molecule HIV-1 Integrase Inhibitor-Binding Site

Proceedings of the National Academy of Sciences - PNAS, 2006-06, Vol.103 (26), p.10080-10085

2006

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Identification of a γc Receptor Antagonist That Prevents Reprogramming of Human Tissue-resident Cytotoxic T Cells by IL15 and IL21

Gastroenterology (New York, N.Y. 1943), 2020-02, Vol.158 (3), p.625-637.e13

2020

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Arrangement of Core Membrane Segments in the MotA/MotB Proton-Channel Complex of Escherichia coli

Biochemistry (Easton), 2004-01, Vol.43 (1), p.35-45

2004

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High-throughput identification of loss-of-function mutations for anti-interferon activity in the influenza A virus NS segment

Journal of virology, 2014-09, Vol.88 (17), p.10157-10164

2014

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Inhibitory profile of a LEDGF/p75 peptide against HIV-1 integrase: Insight into integrase–DNA complex formation and catalysis

FEBS letters, 2008-04, Vol.582 (10), p.1425-1430

2008

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Discovery of novel non-cytotoxic salicylhydrazide containing HIV-1 integrase inhibitors

Bioorganic & medicinal chemistry, 2007-12, Vol.17 (23), p.6472-6475

2007

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Four-tiered π interaction at the dimeric interface of HIV-1 integrase critical for DNA integration and viral infectivity

Virology (New York, N.Y.), 2008-08, Vol.377 (2), p.355-363

2008

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Substituted 2-pyrrolinone inhibitors of HIV-1 integrase

Bioorganic & medicinal chemistry, 2007-11, Vol.17 (22), p.6155-6159

2007

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Quinolone 3-Carboxylic Acid Pharmacophore: Design of Second Generation HIV-1 Integrase Inhibitors

Journal of medicinal chemistry, 2008-03, Vol.51 (5), p.1136-1144

2008

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HIV-1 integrase inhibitors: an emerging clinical reality

Drugs in R&D, 2007, Vol.8 (3), p.155-168

2007

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Discovery of structurally diverse HIV-1 integrase inhibitors based on a chalcone pharmacophore

Bioorganic & medicinal chemistry, 2007-07, Vol.15 (14), p.4985-5002

2007

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Design of second generation HIV-1 integrase inhibitors

Current pharmaceutical design, 2007, Vol.13 (2), p.129-141

2007

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Results From a First‐in‐Human Study of BNZ‐1, a Selective Multicytokine Inhibitor Targeting Members of the Common Gamma (γc) Family of Cytokines

A quantitative high-resolution genetic profile rapidly identifies sequence determinants of hepatitis C viral fitness and drug sensitivity

HIV-1 integrase inhibitors: 2005-2006 update

Functional Constraint Profiling of a Viral Protein Reveals Discordance of Evolutionary Conservation and Functionality

Allosteric Inhibitor Development Targeting HIV-1 Integrase

High-throughput profiling of influenza A virus hemagglutinin gene at single-nucleotide resolution

Blocking interactions between HIV-1 integrase and cellular cofactors: an emerging anti-retroviral strategy

Systematic Identification of H274Y Compensatory Mutations in Influenza A Virus Neuraminidase by High-Throughput Screening

HIV-1 quasispecies delineation by tag linkage deep sequencing

High-throughput profiling of point mutations across the HIV-1 genome

Single-Round, Multiplexed Antibody Mimetic Design through mRNA Display

Correction: Functional Constraint Profiling of a Viral Protein Reveals Discordance of Evolutionary Conservation and Functionality

A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication

Discovery of a Small-Molecule HIV-1 Integrase Inhibitor-Binding Site

Identification of a γc Receptor Antagonist That Prevents Reprogramming of Human Tissue-resident Cytotoxic T Cells by IL15 and IL21

Arrangement of Core Membrane Segments in the MotA/MotB Proton-Channel Complex of Escherichia coli

High-throughput identification of loss-of-function mutations for anti-interferon activity in the influenza A virus NS segment

Inhibitory profile of a LEDGF/p75 peptide against HIV-1 integrase: Insight into integrase–DNA complex formation and catalysis

Discovery of novel non-cytotoxic salicylhydrazide containing HIV-1 integrase inhibitors

Four-tiered π interaction at the dimeric interface of HIV-1 integrase critical for DNA integration and viral infectivity

Substituted 2-pyrrolinone inhibitors of HIV-1 integrase

Quinolone 3-Carboxylic Acid Pharmacophore: Design of Second Generation HIV-1 Integrase Inhibitors

HIV-1 integrase inhibitors: an emerging clinical reality

Discovery of structurally diverse HIV-1 integrase inhibitors based on a chalcone pharmacophore

Design of second generation HIV-1 integrase inhibitors

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