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The Stress-Response Sensor Chop Regulates the Function and Accumulation of Myeloid-Derived Suppressor Cells in Tumors

Immunity (Cambridge, Mass.), 2014-09, Vol.41 (3), p.389-401

2014

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Energy metabolic pathways control the fate and function of myeloid immune cells

Journal of leukocyte biology, 2017-08, Vol.102 (2), p.369-380

2017

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Exogenous lipid uptake induces metabolic and functional reprogramming of tumor-associated myeloid-derived suppressor cells

Oncoimmunology, 2017-10, Vol.6 (10), p.e1344804-e1344804

2017

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PARP-1 Is Critical for Recruitment of Dendritic Cells to the Lung in a Mouse Model of Asthma but Dispensable for Their Differentiation and Function

Mediators of inflammation, 2019-01, Vol.2019, p.1656484-14

2019

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Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies

Cancer immunology research, 2015-11, Vol.3 (11), p.1236-1247

2015

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Targeting PARP-1 with metronomic therapy modulates MDSC suppressive function and enhances anti-PD-1 immunotherapy in colon cancer

Journal for immunotherapy of cancer, 2021-01, Vol.9 (1), p.e001643

2021

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PARP is activated in human asthma and its inhibition by olaparib blocks house dust mite-induced disease in mice

Clinical science (1979), 2015-12, Vol.129 (11), p.951

2015

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Arginine Metabolism in Myeloid Cells Shapes Innate and Adaptive Immunity

Frontiers in immunology, 2017-02, Vol.8, p.93-93

2017

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Redox regulation of T-cell function: from molecular mechanisms to significance in human health and disease

Antioxidants & redox signaling, 2013-04, Vol.18 (12), p.1497

2013

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Increased inflammatory low-density neutrophils in severe obesity and effect of bariatric surgery: Results from case-control and prospective cohort studies

EBioMedicine, 2022-03, Vol.77, p.103910-103910, Article 103910

2022

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l-Arginine depletion blunts antitumor T-cell responses by inducing myeloid-derived suppressor cells

Cancer research (Chicago, Ill.), 2015-01, Vol.75 (2), p.275-283

2015

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The cellular metabolic landscape in the tumor milieu regulates the activity of myeloid infiltrates

Cellular & molecular immunology, 2018-05, Vol.15 (5), p.421-427

2018

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Metabolic reprogramming of myeloid-derived suppressor cells (MDSC) in cancer

Oncoimmunology, 2016-08, Vol.5 (8), p.e1200771-e1200771

2016

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A Quantitative Increase in Regulatory T Cells Controls Development of Vitiligo

Journal of investigative dermatology, 2014-05, Vol.134 (5), p.1285-1294

2014

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Cyclophosphamide Induces Dynamic Alterations in the Host Microenvironments Resulting in a Flt3 Ligand-Dependent Expansion of Dendritic Cells

The Journal of immunology (1950), 2010-02, Vol.184 (4), p.1737-1747

2010

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Pharmacologic Properties and Preclinical Activity of Sasanlimab, A High-affinity Engineered Anti-Human PD-1 Antibody

Molecular cancer therapeutics, 2020-10, Vol.19 (10), p.2105-2116

2020

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A novel patient-derived xenograft model for claudin-low triple-negative breast cancer

Breast cancer research and treatment, 2018-06, Vol.169 (2), p.381-390

2018

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Promoting thiol expression increases the durability of antitumor T-cell functions

Cancer research (Chicago, Ill.), 2014-11, Vol.74 (21), p.6036-6047

2014

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Abstract LB-271: Targeting fatty acid metabolism regulates the immunosuppressive activity of myeloid-derived suppressor cells

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.LB-271-LB-271

2016

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PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4(+) T cell function

Journal of translational medicine, 2015-07, Vol.13 (1), p.225-225, Article 225

2015

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Combinatorial immunotherapy induces tumor-infiltrating CD8+ T cells with distinct functional, migratory, and stem-like properties

Journal for immunotherapy of cancer, 2021-12, Vol.9 (12), p.e003614

2021

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Recovery from Cyclophosphamide-Induced Lymphopenia Results in Expansion of Immature Dendritic Cells Which Can Mediate Enhanced Prime-Boost Vaccination Antitumor Responses In Vivo When Stimulated with the TLR3 Agonist Poly(I:C)

The Journal of immunology (1950), 2009-02, Vol.182 (4), p.2030-2040

2009

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A coreceptor-independent transgenic human TCR mediates anti-tumor and anti-self immunity in mice

The Journal of immunology (1950), 2012-08, Vol.189 (4), p.1627-1638

2012

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T cells expanded in presence of IL-15 exhibit increased antioxidant capacity and innate effector molecules

Cytokine (Philadelphia, Pa.), 2011-08, Vol.55 (2), p.307-317

2011

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Kinetics of rebounding of lymphoid and myeloid cells in mouse peripheral blood, spleen and bone marrow after treatment with cyclophosphamide

Cellular immunology, 2012-03, Vol.276 (1-2), p.67-74

2012

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The Stress-Response Sensor Chop Regulates the Function and Accumulation of Myeloid-Derived Suppressor Cells in Tumors

Energy metabolic pathways control the fate and function of myeloid immune cells

Exogenous lipid uptake induces metabolic and functional reprogramming of tumor-associated myeloid-derived suppressor cells

PARP-1 Is Critical for Recruitment of Dendritic Cells to the Lung in a Mouse Model of Asthma but Dispensable for Their Differentiation and Function

Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies

Targeting PARP-1 with metronomic therapy modulates MDSC suppressive function and enhances anti-PD-1 immunotherapy in colon cancer

PARP is activated in human asthma and its inhibition by olaparib blocks house dust mite-induced disease in mice

Arginine Metabolism in Myeloid Cells Shapes Innate and Adaptive Immunity

Redox regulation of T-cell function: from molecular mechanisms to significance in human health and disease

Increased inflammatory low-density neutrophils in severe obesity and effect of bariatric surgery: Results from case-control and prospective cohort studies

l-Arginine depletion blunts antitumor T-cell responses by inducing myeloid-derived suppressor cells

The cellular metabolic landscape in the tumor milieu regulates the activity of myeloid infiltrates

Metabolic reprogramming of myeloid-derived suppressor cells (MDSC) in cancer

A Quantitative Increase in Regulatory T Cells Controls Development of Vitiligo

Cyclophosphamide Induces Dynamic Alterations in the Host Microenvironments Resulting in a Flt3 Ligand-Dependent Expansion of Dendritic Cells

Pharmacologic Properties and Preclinical Activity of Sasanlimab, A High-affinity Engineered Anti-Human PD-1 Antibody

A novel patient-derived xenograft model for claudin-low triple-negative breast cancer

Promoting thiol expression increases the durability of antitumor T-cell functions

Abstract LB-271: Targeting fatty acid metabolism regulates the immunosuppressive activity of myeloid-derived suppressor cells

PARP inhibition by olaparib or gene knockout blocks asthma-like manifestation in mice by modulating CD4(+) T cell function

Combinatorial immunotherapy induces tumor-infiltrating CD8+ T cells with distinct functional, migratory, and stem-like properties

Recovery from Cyclophosphamide-Induced Lymphopenia Results in Expansion of Immature Dendritic Cells Which Can Mediate Enhanced Prime-Boost Vaccination Antitumor Responses In Vivo When Stimulated with the TLR3 Agonist Poly(I:C)

A coreceptor-independent transgenic human TCR mediates anti-tumor and anti-self immunity in mice

T cells expanded in presence of IL-15 exhibit increased antioxidant capacity and innate effector molecules

Kinetics of rebounding of lymphoid and myeloid cells in mouse peripheral blood, spleen and bone marrow after treatment with cyclophosphamide

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