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Identification of New Mycobacterium tuberculosis Proteasome Inhibitors Using a Knowledge-Based Computational Screening Approach

Molecules (Basel, Switzerland), 2021-04, Vol.26 (8), p.2326

2021

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Assessing the potential impact of COVID-19 Omicron variant: Insight through a fractional piecewise model

Results in physics, 2022-07, Vol.38, p.105652-105652, Article 105652

2022

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Detection of chikungunya virus in the Southern region, Saudi Arabia

Virology journal, 2021-09, Vol.18 (1), p.190-190, Article 190

2021

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Hemoglobinopathies: An update on the prevalence trends in Southern Saudi Arabia

Saudi medical journal, 2021-07, Vol.42 (7), p.784-789

2021

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Oxidative Stress: Mechanistic Insights into Inherited Mitochondrial Disorders and Parkinson's Disease

Journal of clinical medicine, 2017-10, Vol.6 (11), p.100

2017

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The extent to which Islamic education courses at the secondary level incorporate the dimensions of intellectual security in the Kingdom of Saudi Arabia: مدى تضمين مقررات التربية الإسلامية في المرحلة الثانوية بالمملكة العربية السعودية لأبعاد الأمن الفكري

مجلة العلوم التربوية و النفسية, 2022-02, Vol.6 (10), p.109-132

Mesfer Saad Mesfer Al- Shahrani, Mesfer Saad Mesfer Al- Shahrani

2022

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Computational analysis and in vitro evaluation of TMF 104, for its antioxidant, antimicrobial, and anticancer efficacies

Biotechnology and applied biochemistry, 2023-02, Vol.70 (1), p.148-156

2023

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High-throughput virtual screening and preclinical analysis identifies CB-1, a novel potent dual B-Raf/c-Raf inhibitor, effective against wild and mutant variants of B-Raf expression in colorectal carcinoma

Journal of computer-aided molecular design, 2021-12, Vol.35 (12), p.1165-1176

2021

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Computational and in vitro characterization of ICY‐5: A potential candidate promoting mitochondrial apoptosis via the c‐MET and STAT3 pathways

Journal of cellular physiology, 2021-01, Vol.236 (1), p.146-156

2021

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Mitochondrial dysfunction is a key pathological driver of early stage Parkinson's

Acta neuropathologica communications, 2022-09, Vol.10 (1), p.134-134, Article 134

2022

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Anticancer efficacy of 3-(4-isopropyl) benzylidene-8-ethoxy, 6-methyl, chroman-4-one (SBL-060), a novel, dual, estrogen receptor-Akt kinase inhibitor in acute myeloid leukemia cells

Oncology research, 2021-01, Vol.29 (3), p.149-157

2021

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Synergistic efficacies of thymoquinone and standard antibiotics against multi-drug resistant isolates

Saudi medical journal, 2021-02, Vol.42 (2), p.196-204

2021

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Increased mRNA expression of key cytokines among suspected cases of Pneumocystis jirovecii infection

BMC infectious diseases, 2021-01, Vol.21 (1), p.28-28, Article 28

2021

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High-throughput computational screening and in vitro evaluation identifies 5-(4-oxo-4H-3,1-benzoxazin-2-yl)-2-[3-(4-oxo-4H-3,1-benzoxazin-2-yl) phenyl]-1H-isoindole-1,3(2H)-dione (C3), as a novel EGFR-HER2 dual inhibitor in gastric tumors

Oncology research, 2024-01, Vol.32 (2), p.251-259

2024

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Identification of second generation benzylidene chromanone analogues as novel, potent DHODH inhibitors in acute myeloid leukemia cells

Journal of biomolecular structure & dynamics, 2023-09, Vol.41 (13), p.6168-6177

2023

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Long-Term Heat Stress Exposure Induced Poor Semen Parameters and Testicular Damage in Rats by Increasing Oxidative Stress, Sex Hormone Silencing, and Activation of Intrinsic Testicular Apoptosis [348]

Obstetrics and gynecology (New York. 1953), 2015-05, Vol.125 (Supplement 1), p.109-110S

Al-Shahrani, Mesfer Safar

2015

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Impact of Male Obesity on Semen Quality and Serum Sex Hormones

Advances in Urology, 2012-01, Vol.2012 (2012), p.264-267

2012

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Fetomaternal and neonatal outcome of triplet pregnancy. Promising results

Saudi medical journal, 2011-07, Vol.32 (7), p.685

2011

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C-5401331 identified as a novel T-cell immunoglobulin and mucin domain-containing protein 3 (Tim-3) inhibitor to control acute myeloid leukemia (AML) cell proliferation

Medical oncology (Northwood, London, England), 2024-01, Vol.41 (3), p.63-63, Article 63

2024

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Identification by molecular dynamic simulation and in vitro validation of SISB-A1, N-[1-(4-bromophenyl)-3-methyl-1H-pyrazol-5-yl]-2-[(2-oxo-4-phenyl-2H-chromen-7-yl) oxy], as an inhibitor of the AblT315I mutant kinase to combat imatinib resistance in chronic myeloid leukemia

Medical oncology (Northwood, London, England), 2023-10, Vol.40 (11), p.316-316, Article 316

2023

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High-throughput screening and in vitro evaluation of CSB-0914; a novel small molecule NF-κB inhibitor attenuating inflammatory responses through NF-κB, Nrf2 and HO-1 cross-talk

Journal of biomolecular structure & dynamics, 2023-12, p.1-10

2023

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FNF-12, a novel benzylidene-chromanone derivative, attenuates inflammatory response in in vitro and in vivo asthma models mediated by M2-related Th2 cytokines via MAPK and NF-kB signaling

Pharmacological reports, 2022-02, Vol.74 (1), p.96-110

2022

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Pioneering a paradigm shift in tissue engineering and regeneration with polysaccharides and proteins-based scaffolds: A comprehensive review

International journal of biological macromolecules, 2024-04, Vol.265 (Pt 1), p.130643-130643, Article 130643

2024

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GC/MS characterization and computational kinome‐wide screening of pomegranate fruit extract identifies key phytochemicals interacting to CDK kinases implicated in acute myeloid leukemia cells

Journal of food biochemistry, 2022-08, Vol.46 (8), p.e14178-n/a

2022

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Drug-Induced Mitochondrial Toxicity

Drug safety, 2016-07, Vol.39 (7), p.661-674

2016

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Identification of New Mycobacterium tuberculosis Proteasome Inhibitors Using a Knowledge-Based Computational Screening Approach

Assessing the potential impact of COVID-19 Omicron variant: Insight through a fractional piecewise model

Detection of chikungunya virus in the Southern region, Saudi Arabia

Hemoglobinopathies: An update on the prevalence trends in Southern Saudi Arabia

Oxidative Stress: Mechanistic Insights into Inherited Mitochondrial Disorders and Parkinson's Disease

Computational analysis and in vitro evaluation of TMF 104, for its antioxidant, antimicrobial, and anticancer efficacies

High-throughput virtual screening and preclinical analysis identifies CB-1, a novel potent dual B-Raf/c-Raf inhibitor, effective against wild and mutant variants of B-Raf expression in colorectal carcinoma

Computational and in vitro characterization of ICY‐5: A potential candidate promoting mitochondrial apoptosis via the c‐MET and STAT3 pathways

Mitochondrial dysfunction is a key pathological driver of early stage Parkinson's

Anticancer efficacy of 3-(4-isopropyl) benzylidene-8-ethoxy, 6-methyl, chroman-4-one (SBL-060), a novel, dual, estrogen receptor-Akt kinase inhibitor in acute myeloid leukemia cells

Synergistic efficacies of thymoquinone and standard antibiotics against multi-drug resistant isolates

Increased mRNA expression of key cytokines among suspected cases of Pneumocystis jirovecii infection

High-throughput computational screening and in vitro evaluation identifies 5-(4-oxo-4H-3,1-benzoxazin-2-yl)-2-[3-(4-oxo-4H-3,1-benzoxazin-2-yl) phenyl]-1H-isoindole-1,3(2H)-dione (C3), as a novel EGFR-HER2 dual inhibitor in gastric tumors

Identification of second generation benzylidene chromanone analogues as novel, potent DHODH inhibitors in acute myeloid leukemia cells

Long-Term Heat Stress Exposure Induced Poor Semen Parameters and Testicular Damage in Rats by Increasing Oxidative Stress, Sex Hormone Silencing, and Activation of Intrinsic Testicular Apoptosis [348]

Impact of Male Obesity on Semen Quality and Serum Sex Hormones

Fetomaternal and neonatal outcome of triplet pregnancy. Promising results

C-5401331 identified as a novel T-cell immunoglobulin and mucin domain-containing protein 3 (Tim-3) inhibitor to control acute myeloid leukemia (AML) cell proliferation

Identification by molecular dynamic simulation and in vitro validation of SISB-A1, N-[1-(4-bromophenyl)-3-methyl-1H-pyrazol-5-yl]-2-[(2-oxo-4-phenyl-2H-chromen-7-yl) oxy], as an inhibitor of the AblT315I mutant kinase to combat imatinib resistance in chronic myeloid leukemia

High-throughput screening and in vitro evaluation of CSB-0914; a novel small molecule NF-κB inhibitor attenuating inflammatory responses through NF-κB, Nrf2 and HO-1 cross-talk

FNF-12, a novel benzylidene-chromanone derivative, attenuates inflammatory response in in vitro and in vivo asthma models mediated by M2-related Th2 cytokines via MAPK and NF-kB signaling

Pioneering a paradigm shift in tissue engineering and regeneration with polysaccharides and proteins-based scaffolds: A comprehensive review

GC/MS characterization and computational kinome‐wide screening of pomegranate fruit extract identifies key phytochemicals interacting to CDK kinases implicated in acute myeloid leukemia cells

Drug-Induced Mitochondrial Toxicity

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