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The Impact of First-Line Anti-Tubercular Drugs' Pharmacokinetics on Treatment Outcome: A Systematic Review

Clinical pharmacology: advances and applications, 2021-01, Vol.13, p.1-12

2021

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Long-Term Efavirenz Autoinduction and Its Effect on Plasma Exposure in HIV Patients

Clinical pharmacology and therapeutics, 2010-11, Vol.88 (5), p.676-684

2010

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Effect of Genetic Variations in Drug-Metabolizing Enzymes and Drug Transporters on the Pharmacokinetics of Rifamycins: A Systematic Review

Pharmacogenomics and personalized medicine, 2022-01, Vol.15, p.561-571

2022

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High plasma efavirenz level and CYP2B66 are associated with efavirenz-based HAART-induced liver injury in the treatment of naïve HIV patients from Ethiopia: a prospective cohort study

The pharmacogenomics journal, 2012-12, Vol.12 (6), p.499-506

2012

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Rebuttal: Response to the comments by Buck et al. on our published article: Hepatic and renal toxicity and associated factors among HIV‐infected children on antiretroviral therapy: a prospective cohort study; HIV Medicine (2019), 20, 147–156

HIV medicine, 2019-08, Vol.20 (7), p.e13-e14

2019

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Sex and CYP3A5 genotype influence total CYP3A activity: high CYP3A activity and a unique distribution of CYP3A5 variant alleles in Ethiopians

The pharmacogenomics journal, 2011-04, Vol.11 (2), p.130-137

2011

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Explorative Analysis of Treatment Outcomes of Levofloxacin- and Moxifloxacin-Based Regimens and Outcome Predictors in Ethiopian MDR-TB Patients: A Prospective Observational Cohort Study

Infection and drug resistance, 2021-01, Vol.14, p.5473-5489

2021

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CYP2B66 genotype and high efavirenz plasma concentration but not nevirapine are associated with low lumefantrine plasma exposure and poor treatment response in HIV-malaria-coinfected patients

The pharmacogenomics journal, 2016-02, Vol.16 (1), p.88-95

2016

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Pharmacogenetic and pharmacokinetic aspects of CYP3A induction by efavirenz in HIV patients

The pharmacogenomics journal, 2013-12, Vol.13 (6), p.484-489

2013

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Effect of Rifampicin and CYP2B6 Genotype on Long‐Term Efavirenz Autoinduction and Plasma Exposure in HIV Patients With or Without Tuberculosis

Clinical pharmacology and therapeutics, 2011-09, Vol.90 (3), p.406-413

2011

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Elevated levels of circulating CDH5 and FABP1 in association with human drug‐induced liver injury

Liver international, 2017-01, Vol.37 (1), p.132-140

2017

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Long-term effect of efavirenz autoinduction on plasma/peripheral blood mononuclear cell drug exposure and CD4 count is influenced by UGT2B7 and CYP2B6 genotypes among HIV patients

Journal of antimicrobial chemotherapy, 2011-10, Vol.66 (10), p.2350-2361

2011

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High Levels of Methicillin-Resistant Staphylococcus aureus Carriage Among Healthcare Workers at a Teaching Hospital in Addis Ababa Ethiopia: First Evidence Using mecA Detection

Infection and drug resistance, 2022-01, Vol.15, p.3135-3147

2022

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Hepatic and renal toxicity and associated factors among HIV‐infected children on antiretroviral therapy: a prospective cohort study

HIV medicine, 2019-02, Vol.20 (2), p.147-156

2019

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Population Pharmacokinetics of Levofloxacin and Moxifloxacin, and the Probability of Target Attainment in Ethiopian Patients with Multidrug-Resistant Tuberculosis

Infection and drug resistance, 2022-01, Vol.15, p.6839-6852

2022

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Pharmacokinetic and pharmacogenomic modelling of the CYP3A activity marker 4β-hydroxycholesterol during efavirenz treatment and efavirenz/rifampicin co-treatment

Journal of antimicrobial chemotherapy, 2014-12, Vol.69 (12), p.3311-3319

2014

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Global Tuberculosis Report 2020 – Reflections on the Global TB burden, treatment and prevention efforts

International journal of infectious diseases, 2021-12, Vol.113 (Suppl 1), p.S7-S12

2021

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Anti-tuberculosis therapy-induced hepatotoxicity among Ethiopian HIV-positive and negative patients

PloS one, 2008-03, Vol.3 (3), p.e1809

2008

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CYP3A5 Genotype has an Impact on the Metabolism of the HIV Protease Inhibitor Saquinavir

Clinical pharmacology and therapeutics, 2007-05, Vol.81 (5), p.708-712

2007

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The impact of catha edulis (vahl) forssk. ex endl. (celestraceae) (khat) on pharmacokinetics of clinically used drugs

Expert opinion on drug metabolism & toxicology, 2021-09, Vol.17 (9), p.1125-1138

2021

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Pharmacokinetic and pharmacogenomic modelling of the CYP3A activity marker 4 -hydroxycholesterol during efavirenz treatment and efavirenz/rifampicin co-treatment

Journal of antimicrobial chemotherapy, 2014-12, Vol.69 (12), p.3311-3319

2014

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The Proforma Project Presentation

DRUG SAFETY, 2018, Vol.41 (11), p.1107

Aklillu, E

2018

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“Always look at the outliers”: in memoriam Leif Bertilsson

European journal of clinical pharmacology, 2024, Vol.80 (7), p.1111-1112

2024

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Frequent distribution of ultrarapid metabolizers of debrisoquine in an ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles

The Journal of pharmacology and experimental therapeutics, 1996-07, Vol.278 (1), p.441

1996

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Correlation of N-acetyltransferase 2 genotype and acetylation status with plasma isoniazid concentration and its metabolic ratio in ethiopian tuberculosis patients

Scientific reports, 2023-07, Vol.13 (1), p.11438-11438, Article 11438

2023

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The Impact of First-Line Anti-Tubercular Drugs' Pharmacokinetics on Treatment Outcome: A Systematic Review

Long-Term Efavirenz Autoinduction and Its Effect on Plasma Exposure in HIV Patients

Effect of Genetic Variations in Drug-Metabolizing Enzymes and Drug Transporters on the Pharmacokinetics of Rifamycins: A Systematic Review

High plasma efavirenz level and CYP2B66 are associated with efavirenz-based HAART-induced liver injury in the treatment of naïve HIV patients from Ethiopia: a prospective cohort study

Rebuttal: Response to the comments by Buck et al. on our published article: Hepatic and renal toxicity and associated factors among HIV‐infected children on antiretroviral therapy: a prospective cohort study; HIV Medicine (2019), 20, 147–156

Sex and CYP3A5 genotype influence total CYP3A activity: high CYP3A activity and a unique distribution of CYP3A5 variant alleles in Ethiopians

Explorative Analysis of Treatment Outcomes of Levofloxacin- and Moxifloxacin-Based Regimens and Outcome Predictors in Ethiopian MDR-TB Patients: A Prospective Observational Cohort Study

CYP2B66 genotype and high efavirenz plasma concentration but not nevirapine are associated with low lumefantrine plasma exposure and poor treatment response in HIV-malaria-coinfected patients

Pharmacogenetic and pharmacokinetic aspects of CYP3A induction by efavirenz in HIV patients

Effect of Rifampicin and CYP2B6 Genotype on Long‐Term Efavirenz Autoinduction and Plasma Exposure in HIV Patients With or Without Tuberculosis

Elevated levels of circulating CDH5 and FABP1 in association with human drug‐induced liver injury

Long-term effect of efavirenz autoinduction on plasma/peripheral blood mononuclear cell drug exposure and CD4 count is influenced by UGT2B7 and CYP2B6 genotypes among HIV patients

High Levels of Methicillin-Resistant Staphylococcus aureus Carriage Among Healthcare Workers at a Teaching Hospital in Addis Ababa Ethiopia: First Evidence Using mecA Detection

Hepatic and renal toxicity and associated factors among HIV‐infected children on antiretroviral therapy: a prospective cohort study

Population Pharmacokinetics of Levofloxacin and Moxifloxacin, and the Probability of Target Attainment in Ethiopian Patients with Multidrug-Resistant Tuberculosis

Pharmacokinetic and pharmacogenomic modelling of the CYP3A activity marker 4β-hydroxycholesterol during efavirenz treatment and efavirenz/rifampicin co-treatment

Global Tuberculosis Report 2020 – Reflections on the Global TB burden, treatment and prevention efforts

Anti-tuberculosis therapy-induced hepatotoxicity among Ethiopian HIV-positive and negative patients

CYP3A5 Genotype has an Impact on the Metabolism of the HIV Protease Inhibitor Saquinavir

The impact of catha edulis (vahl) forssk. ex endl. (celestraceae) (khat) on pharmacokinetics of clinically used drugs

Pharmacokinetic and pharmacogenomic modelling of the CYP3A activity marker 4 -hydroxycholesterol during efavirenz treatment and efavirenz/rifampicin co-treatment

The Proforma Project Presentation

“Always look at the outliers”: in memoriam Leif Bertilsson

Frequent distribution of ultrarapid metabolizers of debrisoquine in an ethiopian population carrying duplicated and multiduplicated functional CYP2D6 alleles

Correlation of N-acetyltransferase 2 genotype and acetylation status with plasma isoniazid concentration and its metabolic ratio in ethiopian tuberculosis patients

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