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Roles of VCP in human neurodegenerative disorders

Biochemical Society transactions, 2008-02, Vol.36 (Pt 1), p.105-108

Kakizuka, Akira

2008

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VCP relocalization limits mitochondrial activity, GSH depletion and ferroptosis during starvation in PC3 prostate cancer cells

Genes to cells : devoted to molecular & cellular mechanisms, 2021-08, Vol.26 (8), p.570-582

2021

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BTeam, a Novel BRET-based Biosensor for the Accurate Quantification of ATP Concentration within Living Cells

Scientific reports, 2016-12, Vol.6 (1), p.39618-39618, Article 39618

2016

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Hop flower extracts mitigate retinal ganglion cell degeneration in a glaucoma mouse model

Scientific reports, 2020-12, Vol.10 (1), p.21653-21653, Article 21653

2020

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Listeria monocytogenes ActA-mediated escape from autophagic recognition

Nature cell biology, 2009-10, Vol.11 (10), p.1233-1240

2009

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Genetic screening for potassium channel mutations in Japanese autosomal dominant spinocerebellar ataxia

Journal of human genetics, 2020-04, Vol.65 (4), p.363-369

2020

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Ellagic acid, extracted from Sanguisorba officinalis, induces G1 arrest by modulating PTEN activity in B16F10 melanoma cells

Genes to cells : devoted to molecular & cellular mechanisms, 2019-11, Vol.24 (11), p.688-704

2019

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KUS121 attenuates the progression of monosodium iodoacetate-induced osteoarthritis in rats

Scientific reports, 2021-08, Vol.11 (1), p.15651-10, Article 15651

2021

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Author Correction: A VCP modulator, KUS121, as a promising therapeutic agent for post-traumatic osteoarthritis

Scientific reports, 2021-03, Vol.11 (1), p.7442-7442, Article 7442

2021

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Single-cell dynamics of pannexin-1-facilitated programmed ATP loss during apoptosis

eLife, 2020-10, Vol.9

2020

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In Vivo Fluorescent Adenosine 5′-Triphosphate (ATP) Imaging of Drosophila melanogaster and Caenorhabditis elegans by Using a Genetically Encoded Fluorescent ATP Biosensor Optimized for Low Temperatures

Analytical chemistry (Washington), 2013-08, Vol.85 (16), p.7889-7896

2013

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ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

Genes & development, 2002-06, Vol.16 (11), p.1345-1355

2002

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Ontogeny-recapitulating generation and tissue integration of ES cell-derived Purkinje cells

Nature neuroscience, 2010-10, Vol.13 (10), p.1171-1180

2010

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A Highly Sensitive FRET Biosensor for AMPK Exhibits Heterogeneous AMPK Responses among Cells and Organs

Cell reports (Cambridge), 2017-11, Vol.21 (9), p.2628-2638

2017

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Roles of Toll-like receptor 2/4, monoacylglycerol lipase, and cyclooxygenase in social defeat stress-induced prostaglandin E2 synthesis in the brain and their behavioral relevance

Scientific reports, 2019-11, Vol.9 (1), p.1-10, Article 17548

2019

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Glucose-stimulated single pancreatic islets sustain increased cytosolic ATP levels during initial Ca2+ influx and subsequent Ca2+ oscillations

The Journal of biological chemistry, 2014-01, Vol.289 (4), p.2205-2216

2014

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Safety and effectiveness of a novel neuroprotectant, KUS121, in patients with non-arteritic central retinal artery occlusion: An open-label, non-randomized, first-in-humans, phase 1/2 trial

PloS one, 2020-02, Vol.15 (2), p.e0229068

2020

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Novel VCP modulators mitigate major pathologies of rd10, a mouse model of retinitis pigmentosa

Scientific reports, 2014-08, Vol.4 (1), p.5970-5970, Article 5970

2014

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PPARγ Coactivator 1β/ERR Ligand 1 Is an ERR Protein Ligand, Whose Expression Induces a High-Energy Expenditure and Antagonizes Obesity

Proceedings of the National Academy of Sciences - PNAS, 2003-10, Vol.100 (21), p.12378-12383

2003

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Coordinated Regulation of TIP60 and Poly(ADP-Ribose) Polymerase 1 in Damaged-Chromatin Dynamics

Molecular and cellular biology, 2016-05, Vol.36 (10), p.1595-1607

2016

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KUS121, a VCP modulator, has an ameliorating effect on acute and chronic heart failure without calcium loading via maintenance of intracellular ATP levels

Biomedicine & pharmacotherapy, 2024-01, Vol.170, p.115850-115850, Article 115850

2024

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Effect of VCP modulators on gene expression profiles of retinal ganglion cells in an acute injury mouse model

Scientific reports, 2020-03, Vol.10 (1), p.4251, Article 4251

2020

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Protein precipitation: a common etiology in neurodegenerative disorders?

Trends in genetics, 1998-10, Vol.14 (10), p.396-402

Kakizuka, Akira

1998

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In vitro modeling of paraxial mesodermal progenitors derived from induced pluripotent stem cells

PloS one, 2012-10, Vol.7 (10), p.e47078-e47078

2012

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Involvement of valosin‐containing protein (VCP)/p97 in the formation and clearance of abnormal protein aggregates

Genes to cells : devoted to molecular & cellular mechanisms, 2007-07, Vol.12 (7), p.889-901

2007

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Roles of VCP in human neurodegenerative disorders

VCP relocalization limits mitochondrial activity, GSH depletion and ferroptosis during starvation in PC3 prostate cancer cells

BTeam, a Novel BRET-based Biosensor for the Accurate Quantification of ATP Concentration within Living Cells

Hop flower extracts mitigate retinal ganglion cell degeneration in a glaucoma mouse model

Listeria monocytogenes ActA-mediated escape from autophagic recognition

Genetic screening for potassium channel mutations in Japanese autosomal dominant spinocerebellar ataxia

Ellagic acid, extracted from Sanguisorba officinalis, induces G1 arrest by modulating PTEN activity in B16F10 melanoma cells

KUS121 attenuates the progression of monosodium iodoacetate-induced osteoarthritis in rats

Author Correction: A VCP modulator, KUS121, as a promising therapeutic agent for post-traumatic osteoarthritis

Single-cell dynamics of pannexin-1-facilitated programmed ATP loss during apoptosis

In Vivo Fluorescent Adenosine 5′-Triphosphate (ATP) Imaging of Drosophila melanogaster and Caenorhabditis elegans by Using a Genetically Encoded Fluorescent ATP Biosensor Optimized for Low Temperatures

ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats

Ontogeny-recapitulating generation and tissue integration of ES cell-derived Purkinje cells

A Highly Sensitive FRET Biosensor for AMPK Exhibits Heterogeneous AMPK Responses among Cells and Organs

Roles of Toll-like receptor 2/4, monoacylglycerol lipase, and cyclooxygenase in social defeat stress-induced prostaglandin E2 synthesis in the brain and their behavioral relevance

Glucose-stimulated single pancreatic islets sustain increased cytosolic ATP levels during initial Ca2+ influx and subsequent Ca2+ oscillations

Safety and effectiveness of a novel neuroprotectant, KUS121, in patients with non-arteritic central retinal artery occlusion: An open-label, non-randomized, first-in-humans, phase 1/2 trial

Novel VCP modulators mitigate major pathologies of rd10, a mouse model of retinitis pigmentosa

PPARγ Coactivator 1β/ERR Ligand 1 Is an ERR Protein Ligand, Whose Expression Induces a High-Energy Expenditure and Antagonizes Obesity

Coordinated Regulation of TIP60 and Poly(ADP-Ribose) Polymerase 1 in Damaged-Chromatin Dynamics

KUS121, a VCP modulator, has an ameliorating effect on acute and chronic heart failure without calcium loading via maintenance of intracellular ATP levels

Effect of VCP modulators on gene expression profiles of retinal ganglion cells in an acute injury mouse model

Protein precipitation: a common etiology in neurodegenerative disorders?

In vitro modeling of paraxial mesodermal progenitors derived from induced pluripotent stem cells

Involvement of valosin‐containing protein (VCP)/p97 in the formation and clearance of abnormal protein aggregates

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