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Evaluation of Pharmacokinetics, Safety, and Drug‐Drug Interactions of an Oral Suspension of Edaravone in Healthy Adults

Clinical pharmacology in drug development, 2021-10, Vol.10 (10), p.1174-1187

2021

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Edaravone for treatment of early-stage ALS – Authors' reply

Lancet neurology, 2017-10, Vol.16 (10), p.772-772

2017

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Edaravone and its clinical development for amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis and frontotemporal degeneration, 2017-10, Vol.18 (sup1), p.5-10

2017

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An Open-label, Single-dose Study to Evaluate the Pharmacokinetic Variables of Edaravone in Subjects with Mild, Moderate, or No Renal Impairment

Clinical therapeutics, 2020-09, Vol.42 (9), p.1699-1714

2020

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Confirmatory double-blind, parallel-group, placebo-controlled study of efficacy and safety of edaravone (MCI-186) in amyotrophic lateral sclerosis patients

Amyotrophic lateral sclerosis and frontotemporal degeneration, 2014-12, Vol.15 (7-8), p.610-617

2014

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Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial

Lancet neurology, 2017-07, Vol.16 (7), p.505-512

2017

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Food Effect Study to Assess the Impact on Edaravone Pharmacokinetic Profiles in Healthy Participants

Clinical therapeutics, 2022-12, Vol.44 (12), p.1552-1565

2022

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Open-label, Single-dose Studies of the Pharmacokinetics of Edaravone in Subjects with Mild, Moderate, or Severe Hepatic Impairment Compared to Subjects with Normal Hepatic Functioning

Clinical therapeutics, 2020-08, Vol.42 (8), p.1467-1482.e4

2020

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Pharmacokinetics of edaravone oral suspension in patients with amyotrophic lateral sclerosis

Clinical therapeutics, 2023-12, Vol.45 (12), p.1251-1258

2023

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A post-hoc subgroup analysis of outcomes in the first phase III clinical study of edaravone (MCI-186) in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis and frontotemporal degeneration, 2017-10, Vol.18 (sup1), p.11-19

2017

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Exploratory double-blind, parallel-group, placebo-controlled study of edaravone (MCI-186) in amyotrophic lateral sclerosis (Japan ALS severity classification: Grade 3, requiring assistance for eating, excretion or ambulation)

Amyotrophic lateral sclerosis and frontotemporal degeneration, 2017-10, Vol.18 (sup1), p.40-48

2017

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A Randomized, Single‐Blind, Placebo‐Controlled, 3‐Way Crossover Study to Evaluate the Effect of Therapeutic and Supratherapeutic Doses of Edaravone on QT/QTc Interval in Healthy Subjects

Clinical pharmacology in drug development, 2021-01, Vol.10 (1), p.46-56

2021

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Hypocholesterolemic effect of chitosan in adult males

Bioscience, biotechnology, and biochemistry, 1993, Vol.57 (9), p.1439-1444

1993

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Open-label 24-week extension study of edaravone (MCI-186) in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis and frontotemporal degeneration, 2017-10, Vol.18 (sup1), p.55-63

2017

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Exploratory double-blind, parallel-group, placebo-controlled extension study of edaravone (MCI-186) in amyotrophic lateral sclerosis

Amyotrophic lateral sclerosis and frontotemporal degeneration, 2017-10, Vol.18 (sup1), p.20-31

2017

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Introducing “Active Learning” into an Experimental Practice Class for Students of a Registered Dietitian Course: Working towards a Better Understanding of Scientific Literacy and Generic skills

Journal of Science Education in Japan, 2017, Vol.41(2), pp.179-192

2017

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The Use of a Hands-on Gene Experiment to Foster Scientific Literacy in Dietetics Training

Journal of Science Education in Japan, 2016, Vol.40(1), pp.98-112

2016

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Patient Registry and Biobank for Reverse Translational Research on Neurodegenerative Diseases

Rinsho yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics, 2017/07/31, Vol.48(4), pp.141-147

2017

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管理栄養士養成実験実習におけるアクティブ・ラーニングの活用―科学的リテラシーと社会人基礎力の観点から

科学教育研究, 2017, Vol.41(2), pp.179-192

2017

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栄養士養成教育における科学的リテラシーの観点を活用する試み―遺伝子解析技術体験を介した食と健康に関する学び

科学教育研究, 2016, Vol.40(1), pp.98-112

2016

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神経変性疾患に対するリバーストランスレーショナルリサーチの基盤としての患者レジストリおよびバイオバンク

臨床薬理, 2017/07/31, Vol.48(4), pp.141-147

2017

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Effects of tripalmitin and safflower oil on the content of short-chain fatty acids in the cecum and on the fecal excretion of lipids in rats

Bioscience, biotechnology, and biochemistry, 1994, Vol.58 (7), p.1316-1317

1994

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Investigation of antimicrobial susceptibility of Group B streptococci with reduced penicillin susceptibility during the past five years from 2010 to 2014

Japanese Journal of Medical Technology, 2016/05/25, Vol.65(6), pp.655-659

2016

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Volatile Antiallergic Principles from a Traditional Herbal Prescription of Kampo Medicine

Phytotherapy research, 1996-05, Vol.10 (3), p.238-241

1996

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Throughput Improvement of IEEE802.11DCF with Adaptive RTS/CTS Control on the Basis of Existence of Hidden Terminals

2011 International Conference on Complex, Intelligent, and Software Intensive Systems, 2011, p.46-52

2011

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Evaluation of Pharmacokinetics, Safety, and Drug‐Drug Interactions of an Oral Suspension of Edaravone in Healthy Adults

Edaravone for treatment of early-stage ALS – Authors' reply

Edaravone and its clinical development for amyotrophic lateral sclerosis

An Open-label, Single-dose Study to Evaluate the Pharmacokinetic Variables of Edaravone in Subjects with Mild, Moderate, or No Renal Impairment

Confirmatory double-blind, parallel-group, placebo-controlled study of efficacy and safety of edaravone (MCI-186) in amyotrophic lateral sclerosis patients

Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial

Food Effect Study to Assess the Impact on Edaravone Pharmacokinetic Profiles in Healthy Participants

Open-label, Single-dose Studies of the Pharmacokinetics of Edaravone in Subjects with Mild, Moderate, or Severe Hepatic Impairment Compared to Subjects with Normal Hepatic Functioning

Pharmacokinetics of edaravone oral suspension in patients with amyotrophic lateral sclerosis

A post-hoc subgroup analysis of outcomes in the first phase III clinical study of edaravone (MCI-186) in amyotrophic lateral sclerosis

Exploratory double-blind, parallel-group, placebo-controlled study of edaravone (MCI-186) in amyotrophic lateral sclerosis (Japan ALS severity classification: Grade 3, requiring assistance for eating, excretion or ambulation)

A Randomized, Single‐Blind, Placebo‐Controlled, 3‐Way Crossover Study to Evaluate the Effect of Therapeutic and Supratherapeutic Doses of Edaravone on QT/QTc Interval in Healthy Subjects

Hypocholesterolemic effect of chitosan in adult males

Open-label 24-week extension study of edaravone (MCI-186) in amyotrophic lateral sclerosis

Exploratory double-blind, parallel-group, placebo-controlled extension study of edaravone (MCI-186) in amyotrophic lateral sclerosis

Introducing “Active Learning” into an Experimental Practice Class for Students of a Registered Dietitian Course: Working towards a Better Understanding of Scientific Literacy and Generic skills

The Use of a Hands-on Gene Experiment to Foster Scientific Literacy in Dietetics Training

Patient Registry and Biobank for Reverse Translational Research on Neurodegenerative Diseases

管理栄養士養成実験実習におけるアクティブ・ラーニングの活用―科学的リテラシーと社会人基礎力の観点から

栄養士養成教育における科学的リテラシーの観点を活用する試み―遺伝子解析技術体験を介した食と健康に関する学び

神経変性疾患に対するリバーストランスレーショナルリサーチの基盤としての患者レジストリおよびバイオバンク

Effects of tripalmitin and safflower oil on the content of short-chain fatty acids in the cecum and on the fecal excretion of lipids in rats

Investigation of antimicrobial susceptibility of Group B streptococci with reduced penicillin susceptibility during the past five years from 2010 to 2014

Volatile Antiallergic Principles from a Traditional Herbal Prescription of Kampo Medicine

Throughput Improvement of IEEE802.11DCF with Adaptive RTS/CTS Control on the Basis of Existence of Hidden Terminals

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