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The neurophysiology and pathology of brain zinc

The Journal of neuroscience, 2011-11, Vol.31 (45), p.16076-16085

2011

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Convergent Ca²⁺ and Zn²⁺ signaling regulates apoptotic Kv2.1 K⁺ currents

Proceedings of the National Academy of Sciences - PNAS, 2013-08, Vol.110 (34), p.13988-13993

2013

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ERK signaling leads to mitochondrial dysfunction in extracellular zinc-induced neurotoxicity

Journal of neurochemistry, 2010-07, Vol.114 (2), p.452-461

2010

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Homeostatic regulation of KCC2 activity by the zinc receptor mZnR/GPR39 during seizures

Neurobiology of disease, 2015-09, Vol.81, p.4-13

2015

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Neurodevelopmental Consequences of Dietary Zinc Deficiency: A Status Report

Biological trace element research, 2023-12, Vol.201 (12), p.5616-5639

2023

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A human Tau expressing zebrafish model of progressive supranuclear palsy identifies Brd4 as a regulator of microglial synaptic elimination

Nature communications, 2024-09, Vol.15 (1), p.8195-20, Article 8195

2024

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Upregulation of KCC2 activity by zinc-mediated neurotransmission via the mZnR/GPR39 receptor

The Journal of neuroscience, 2011-09, Vol.31 (36), p.12916-12926

2011

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Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology

PLoS genetics, 2017-01, Vol.13 (1), p.e1006536-e1006536

2017

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Metals and neurodegeneration

Neurobiology of disease, 2015-09, Vol.81, p.1-3

2015

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Redox regulation of intracellular zinc: molecular signaling in the life and death of neurons

Antioxidants & redox signaling, 2011-10, Vol.15 (8), p.2249-2263

2011

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Lessons from Recent Advances in Ischemic Stroke Management and Targeting Kv2.1 for Neuroprotection

International journal of molecular sciences, 2020-08, Vol.21 (17), p.6107

2020

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The physiological and pathophysiological roles of copper in the nervous system

The European journal of neuroscience, 2024-07, Vol.60 (1), p.3505-3543

2024

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The Multifaceted Roles of Zinc in Neuronal Mitochondrial Dysfunction

Biomedicines, 2021-04, Vol.9 (5), p.489

2021

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Synaptic Zn2+ inhibits neurotransmitter release by promoting endocannabinoid synthesis

The Journal of neuroscience, 2013-05, Vol.33 (22), p.9259-9272

2013

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The Redox Biology of Excitotoxic Processes: The NMDA Receptor, TOPA Quinone, and the Oxidative Liberation of Intracellular Zinc

Frontiers in neuroscience, 2020-07, Vol.14, p.778

2020

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Imprecision in Precision Medicine: Differential Response of a Disease-Linked GluN2A Mutant to NMDA Channel Blockers

Frontiers in pharmacology, 2021-10, Vol.12, p.773455-773455

2021

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SNAP23 regulates KCC2 membrane insertion and activity following mZnR/GPR39 activation in hippocampalneurons

iScience, 2022-02, Vol.25 (2), p.103751-103751, Article 103751

2022

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Regulation of Pro-Apoptotic Phosphorylation of Kv2.1 K+ Channels

PloS one, 2015-06, Vol.10 (6), p.e0129498-e0129498

2015

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Regulation of apoptotic potassium currents by coordinated zinc-dependent signalling

The Journal of physiology, 2009-09, Vol.587 (18), p.4393-4404

2009

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Selective Inhibition of Mitogen-Activated Protein Kinase Phosphatases by Zinc Accounts for Extracellular Signal-Regulated Kinase 1/2-Dependent Oxidative Neuronal Cell Death

Molecular pharmacology, 2008-10, Vol.74 (4), p.1141-1151

2008

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Mediation of Neuronal Apoptosis by Kv2.1-Encoded Potassium Channels

The Journal of neuroscience, 2003-06, Vol.23 (12), p.4798-4802

2003

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Peroxynitrite-Induced Neuronal Apoptosis Is Mediated by Intracellular Zinc Release and 12-Lipoxygenase Activation

The Journal of neuroscience, 2004-11, Vol.24 (47), p.10616-10627

2004

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Apoptotic surge of potassium currents is mediated by p38 phosphorylation of Kv2.1

Proceedings of the National Academy of Sciences - PNAS, 2007-02, Vol.104 (9), p.3568-3573

2007

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The Function and Regulation of Zinc in the Brain

Neuroscience, 2021-03, Vol.457, p.235-258

2021

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Caspase 3 Activation Is Essential for Neuroprotection in Preconditioning

Proceedings of the National Academy of Sciences - PNAS, 2003-01, Vol.100 (2), p.715-720

2003

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The neurophysiology and pathology of brain zinc

Convergent Ca²⁺ and Zn²⁺ signaling regulates apoptotic Kv2.1 K⁺ currents

ERK signaling leads to mitochondrial dysfunction in extracellular zinc-induced neurotoxicity

Homeostatic regulation of KCC2 activity by the zinc receptor mZnR/GPR39 during seizures

Neurodevelopmental Consequences of Dietary Zinc Deficiency: A Status Report

A human Tau expressing zebrafish model of progressive supranuclear palsy identifies Brd4 as a regulator of microglial synaptic elimination

Upregulation of KCC2 activity by zinc-mediated neurotransmission via the mZnR/GPR39 receptor

Molecular Mechanism of Disease-Associated Mutations in the Pre-M1 Helix of NMDA Receptors and Potential Rescue Pharmacology

Metals and neurodegeneration

Redox regulation of intracellular zinc: molecular signaling in the life and death of neurons

Lessons from Recent Advances in Ischemic Stroke Management and Targeting Kv2.1 for Neuroprotection

The physiological and pathophysiological roles of copper in the nervous system

The Multifaceted Roles of Zinc in Neuronal Mitochondrial Dysfunction

Synaptic Zn2+ inhibits neurotransmitter release by promoting endocannabinoid synthesis

The Redox Biology of Excitotoxic Processes: The NMDA Receptor, TOPA Quinone, and the Oxidative Liberation of Intracellular Zinc

Imprecision in Precision Medicine: Differential Response of a Disease-Linked GluN2A Mutant to NMDA Channel Blockers

SNAP23 regulates KCC2 membrane insertion and activity following mZnR/GPR39 activation in hippocampalneurons

Regulation of Pro-Apoptotic Phosphorylation of Kv2.1 K+ Channels

Regulation of apoptotic potassium currents by coordinated zinc-dependent signalling

Selective Inhibition of Mitogen-Activated Protein Kinase Phosphatases by Zinc Accounts for Extracellular Signal-Regulated Kinase 1/2-Dependent Oxidative Neuronal Cell Death

Mediation of Neuronal Apoptosis by Kv2.1-Encoded Potassium Channels

Peroxynitrite-Induced Neuronal Apoptosis Is Mediated by Intracellular Zinc Release and 12-Lipoxygenase Activation

Apoptotic surge of potassium currents is mediated by p38 phosphorylation of Kv2.1

The Function and Regulation of Zinc in the Brain

Caspase 3 Activation Is Essential for Neuroprotection in Preconditioning

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