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How lipid droplets “TAG” along: Glycerolipid synthetic enzymes and lipid storage

Biochimica et biophysica acta. Molecular and cell biology of lipids, 2017-10, Vol.1862 (10), p.1131-1145

2017

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Crystal structure of a lipin/Pah phosphatidic acid phosphatase

Nature communications, 2020-03, Vol.11 (1), p.1309-1309, Article 1309

2020

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Differential reliance of CTD-nuclear envelope phosphatase 1 on its regulatory subunit in ER lipid synthesis and storage

Molecular biology of the cell, 2024-07, Vol.35 (7), p.ar101

2024

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Alkaline ceramidase catalyzes the hydrolysis of ceramides via a catalytic mechanism shared by Zn2+-dependent amidases

PloS one, 2022-09, Vol.17 (9), p.e0271540-e0271540

2022

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Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation

Nature communications, 2023-06, Vol.14 (1), p.3204-16, Article 3204

2023

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Roles and regulation of neutral sphingomyelinase-2 in cellular and pathological processes

Advances in biological regulation, 2015-01, Vol.57, p.24-41

2015

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PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport

Developmental cell, 2023-07, Vol.58 (14), p.1250-1265.e6

2023

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Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents

Nature communications, 2021-10, Vol.12 (1), p.5885-5885, Article 5885

2021

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The middle lipin domain adopts a membrane-binding dimeric protein fold

Nature communications, 2021-08, Vol.12 (1), p.4718-14, Article 4718

2021

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Measurement of neutral ceramidase activity in vitro and in vivo

Analytical biochemistry, 2022-04, Vol.643, p.114577-114577, Article 114577

2022

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Sphingolipid metabolism and neutral sphingomyelinases

Handbook of experimental pharmacology, 2013 (215), p.57

2013

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Structure and Dynamics of Human Perilipin 3 Membrane Association

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

2022

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Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB

The EMBO journal, 2022-09, Vol.41 (17), p.e110698-n/a

2022

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Structure and mechanism of the human CTDNEP1-NEP1R1 membrane protein phosphatase complex necessary to maintain ER membrane morphology

Proceedings of the National Academy of Sciences - PNAS, 2024-05, Vol.121 (22), p.e2321167121

2024

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Structure of human nSMase2 reveals an interdomain allosteric activation mechanism for ceramide generation

Proceedings of the National Academy of Sciences - PNAS, 2017-07, Vol.114 (28), p.E5549-E5558

2017

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Structural Basis for Ceramide Recognition and Hydrolysis by Human Neutral Ceramidase

Structure (London), 2015-08, Vol.23 (8), p.1482-1491

2015

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Crystal structure of human PLD1 provides insight into activation by PI(4,5)P2 and RhoA

Nature chemical biology, 2020-04, Vol.16 (4), p.400-407

2020

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Crystal structure of human PLD1 provides insight into activation by PI(4,5)P 2 and RhoA

Nature chemical biology, 2020-04, Vol.16 (4), p.400

2020

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HAMP domain conformers that propagate opposite signals in bacterial chemoreceptors

PLoS biology, 2013-02, Vol.11 (2), p.e1001479-e1001479

2013

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Abstract 2576: Structure and dynamics of human perilipin 3 membrane association

The Journal of biological chemistry, 2023, Vol.299 (3), p.103850, Article 103850

Airola, Michael

2023

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Snapshots of lipid synthesis and fat storage

The FASEB journal, 2022-05, Vol.36 (S1), p.n/a

Airola, Michael

2022

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Structure of Concatenated HAMP Domains Provides a Mechanism for Signal Transduction

Structure (London), 2010-03, Vol.18 (4), p.436-448

2010

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Structure and regulation of human phospholipase D

Advances in biological regulation, 2021-01, Vol.79, p.100783-100783, Article 100783

2021

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Targeting Sterylglucosidase A to Treat Aspergillus fumigatus Infections

mBio, 2023-04, Vol.14 (2), p.e0033923-e0033923

2023

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Mek1 coordinates meiotic progression with DNA break repair by directly phosphorylating and inhibiting the yeast pachytene exit regulator Ndt80

PLoS genetics, 2018-11, Vol.14 (11), p.e1007832-e1007832

2018

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How lipid droplets “TAG” along: Glycerolipid synthetic enzymes and lipid storage

Crystal structure of a lipin/Pah phosphatidic acid phosphatase

Differential reliance of CTD-nuclear envelope phosphatase 1 on its regulatory subunit in ER lipid synthesis and storage

Alkaline ceramidase catalyzes the hydrolysis of ceramides via a catalytic mechanism shared by Zn2+-dependent amidases

Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation

Roles and regulation of neutral sphingomyelinase-2 in cellular and pathological processes

PLIN5 interacts with FATP4 at membrane contact sites to promote lipid droplet-to-mitochondria fatty acid transport

Structure and inhibition of Cryptococcus neoformans sterylglucosidase to develop antifungal agents

The middle lipin domain adopts a membrane-binding dimeric protein fold

Measurement of neutral ceramidase activity in vitro and in vivo

Sphingolipid metabolism and neutral sphingomyelinases

Structure and Dynamics of Human Perilipin 3 Membrane Association

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB

Structure and mechanism of the human CTDNEP1-NEP1R1 membrane protein phosphatase complex necessary to maintain ER membrane morphology

Structure of human nSMase2 reveals an interdomain allosteric activation mechanism for ceramide generation

Structural Basis for Ceramide Recognition and Hydrolysis by Human Neutral Ceramidase

Crystal structure of human PLD1 provides insight into activation by PI(4,5)P2 and RhoA

Crystal structure of human PLD1 provides insight into activation by PI(4,5)P 2 and RhoA

HAMP domain conformers that propagate opposite signals in bacterial chemoreceptors

Abstract 2576: Structure and dynamics of human perilipin 3 membrane association

Snapshots of lipid synthesis and fat storage

Structure of Concatenated HAMP Domains Provides a Mechanism for Signal Transduction

Structure and regulation of human phospholipase D

Targeting Sterylglucosidase A to Treat Aspergillus fumigatus Infections

Mek1 coordinates meiotic progression with DNA break repair by directly phosphorylating and inhibiting the yeast pachytene exit regulator Ndt80

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