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JAK2V617F promotes replication fork stalling with disease-restricted impairment of the intra-S checkpoint response

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (42), p.15190-15195

2014

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RECQL5 Suppresses Oncogenic JAK2-Induced Replication Stress and Genomic Instability

Cell reports (Cambridge), 2015-12, Vol.13 (11), p.2345-2352

2015

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PwRn1, a novel Ty3/gypsy-like retrotransposon of Paragonimus westermani: molecular characters and its differentially preserved mobile potential according to host chromosomal polyploidy

BMC genomics, 2008-10, Vol.9 (1), p.482-482, Article 482

2008

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JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F–positive essential thrombocythemia

Blood, 2010-09, Vol.116 (9), p.1528-1538

2010

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The FANCM Ortholog Fml1 Promotes Recombination at Stalled Replication Forks and Limits Crossing Over during DNA Double-Strand Break Repair

Molecular cell, 2008-10, Vol.32 (1), p.118-128

2008

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Mus81-Eme1 and Rqh1 Involvement in Processing Stalled and Collapsed Replication Forks

The Journal of biological chemistry, 2002-09, Vol.277 (36), p.32753-32759

2002

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Replication fork blockage by RTS1 at an ectopic site promotes recombination in fission yeast

The EMBO journal, 2005-06, Vol.24 (11), p.2011-2023

2005

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The Role of the SAP Motif in Promoting Holliday Junction Binding and Resolution by SpCCE1

The Journal of biological chemistry, 2003-08, Vol.278 (31), p.29121-29129

2003

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ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNFα-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth

Molecular cancer therapeutics, 2018-07, Vol.17 (7), p.1381-1391

2018

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Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein–Protein Interaction

Journal of medicinal chemistry, 2021-04, Vol.64 (7), p.4071-4088

2021

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The RecQ DNA helicase Rqh1 constrains Exonuclease 1-dependent recombination at stalled replication forks

Scientific reports, 2016-03, Vol.6 (1), p.22837-22837, Article 22837

2016

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The Recql5 Helicase Is a Novel Downstream Target of Jak2V617F and Maintains Genome Stability in Response to Replication Stress

Blood, 2014-12, Vol.124 (21), p.822-822

2014

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Molecular mechanisms that control and promote homologous recombination in fission yeast

Ahn, Jong Sook

2005

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DNA methylation loss promotes immune evasion of tumours with high mutation and copy number load

Nature communications, 2019-09, Vol.10 (1), p.4278-12, Article 4278

2019

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Resilience buffers the impact of traumatic events on the development of PTSD symptoms in firefighters

Journal of affective disorders, 2014-06, Vol.162, p.128-133

2014

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Predicting clinical benefit of immunotherapy by antigenic or functional mutations affecting tumour immunogenicity

Nature communications, 2020-02, Vol.11 (1), p.951-951, Article 951

2020

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Validation of the 2022 European LeukemiaNet risk stratification for acute myeloid leukemia

Scientific reports, 2024-04, Vol.14 (1), p.8517-8517

2024

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Targeting cancer cells with reactive oxygen and nitrogen species generated by atmospheric-pressure air plasma

PloS one, 2014-01, Vol.9 (1), p.e86173-e86173

2014

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Lazertinib in patients with EGFR mutation-positive advanced non-small-cell lung cancer: results from the dose escalation and dose expansion parts of a first-in-human, open-label, multicentre, phase 1–2 study

The lancet oncology, 2019-12, Vol.20 (12), p.1681-1690

2019

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First-SIGNAL: First-Line Single-Agent Iressa Versus Gemcitabine and Cisplatin Trial in Never-Smokers With Adenocarcinoma of the Lung

Journal of clinical oncology, 2012-04, Vol.30 (10), p.1122-1128

2012

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Atomic‐Level Customization of 4 in. Transition Metal Dichalcogenide Multilayer Alloys for Industrial Applications

Advanced materials (Weinheim), 2019-07, Vol.31 (29), p.e1901405-n/a

2019

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Genomic landscape of acquired resistance to third‐generation EGFR tyrosine kinase inhibitors in EGFR T790M‐mutant non–small cell lung cancer

Cancer, 2020-06, Vol.126 (11), p.2704-2712

2020

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Comprehensive Clinical and Genetic Characterization of Hyperprogression Based on Volumetry in Advanced Non–Small Cell Lung Cancer Treated With Immune Checkpoint Inhibitor

Journal of thoracic oncology, 2019-09, Vol.14 (9), p.1608-1618

2019

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JAK2V617F promotes replication fork stalling with disease-restricted impairment of the intra-S checkpoint response

RECQL5 Suppresses Oncogenic JAK2-Induced Replication Stress and Genomic Instability

PwRn1, a novel Ty3/gypsy-like retrotransposon of Paragonimus westermani: molecular characters and its differentially preserved mobile potential according to host chromosomal polyploidy

JAK2 V617F impairs hematopoietic stem cell function in a conditional knock-in mouse model of JAK2 V617F–positive essential thrombocythemia

The FANCM Ortholog Fml1 Promotes Recombination at Stalled Replication Forks and Limits Crossing Over during DNA Double-Strand Break Repair

Mus81-Eme1 and Rqh1 Involvement in Processing Stalled and Collapsed Replication Forks

Replication fork blockage by RTS1 at an ectopic site promotes recombination in fission yeast

The Role of the SAP Motif in Promoting Holliday Junction Binding and Resolution by SpCCE1

ASTX660, a Novel Non-peptidomimetic Antagonist of cIAP1/2 and XIAP, Potently Induces TNFα-Dependent Apoptosis in Cancer Cell Lines and Inhibits Tumor Growth

Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein–Protein Interaction

The RecQ DNA helicase Rqh1 constrains Exonuclease 1-dependent recombination at stalled replication forks

The Recql5 Helicase Is a Novel Downstream Target of Jak2V617F and Maintains Genome Stability in Response to Replication Stress

Molecular mechanisms that control and promote homologous recombination in fission yeast

DNA methylation loss promotes immune evasion of tumours with high mutation and copy number load

Resilience buffers the impact of traumatic events on the development of PTSD symptoms in firefighters

Predicting clinical benefit of immunotherapy by antigenic or functional mutations affecting tumour immunogenicity

Validation of the 2022 European LeukemiaNet risk stratification for acute myeloid leukemia

Targeting cancer cells with reactive oxygen and nitrogen species generated by atmospheric-pressure air plasma

Lazertinib in patients with EGFR mutation-positive advanced non-small-cell lung cancer: results from the dose escalation and dose expansion parts of a first-in-human, open-label, multicentre, phase 1–2 study

First-SIGNAL: First-Line Single-Agent Iressa Versus Gemcitabine and Cisplatin Trial in Never-Smokers With Adenocarcinoma of the Lung

Atomic‐Level Customization of 4 in. Transition Metal Dichalcogenide Multilayer Alloys for Industrial Applications

Genomic landscape of acquired resistance to third‐generation EGFR tyrosine kinase inhibitors in EGFR T790M‐mutant non–small cell lung cancer

Comprehensive Clinical and Genetic Characterization of Hyperprogression Based on Volumetry in Advanced Non–Small Cell Lung Cancer Treated With Immune Checkpoint Inhibitor

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