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Essential long-range action of Wingless/Wnt in adult intestinal compartmentalization

PLoS genetics, 2019-06, Vol.15 (6), p.e1008111-e1008111

2019

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Regulation of Stem Cell Proliferation and Cell Fate Specification by Wingless/Wnt Signaling Gradients Enriched at Adult Intestinal Compartment Boundaries

PLoS genetics, 2016-02, Vol.12 (2), p.e1005822-e1005822

2016

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The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling

Nature communications, 2021-09, Vol.12 (1), p.5263-5263, Article 5263

2021

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Dual Roles for Membrane Association of Drosophila Axin in Wnt Signaling

PLoS genetics, 2016-12, Vol.12 (12), p.e1006494-e1006494

2016

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G protein Gαi functions immediately downstream of Smoothened in Hedgehog signalling

Nature (London), 2008-12, Vol.456 (7224), p.967-970

2008

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Wnt pathway activation by ADP-ribosylation

Nature communications, 2016-05, Vol.7 (1), p.11430-14, Article 11430

2016

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Axin phosphorylation in both Wnt-off and Wnt-on states requires the tumor suppressor APC

PLoS genetics, 2018-02, Vol.14 (2), p.e1007178-e1007178

2018

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Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling

eLife, 2016-12, Vol.5

2016

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Wingless/Wnt Signaling in Intestinal Development, Homeostasis, Regeneration and Tumorigenesis: A Drosophila Perspective

Journal of developmental biology, 2018-03, Vol.6 (2), p.8

2018

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The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6

Nature communications, 2023-10, Vol.14 (1), p.6174-6174, Article 6174

2023

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Casein Kinase 1α as a Regulator of Wnt-Driven Cancer

International journal of molecular sciences, 2020-08, Vol.21 (16), p.5940

2020

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The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling

Nature communications, 2023-10, Vol.14 (1), p.6173-6173, Article 6173

2023

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Intestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing

PLoS genetics, 2017-07, Vol.13 (7), p.e1006870

2017

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A Context-Dependent Role for the RNF146 Ubiquitin Ligase in Wingless/Wnt Signaling in Drosophila

Genetics (Austin), 2019-03, Vol.211 (3), p.913-923

2019

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Evidence for tankyrases as antineoplastic targets in lung cancer

BMC cancer, 2013-04, Vol.13 (1), p.211-211, Article 211

2013

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Ileal Crohn's Disease Exhibits Reduced Activity of Phospholipase C-β3-Dependent Wnt/β-Catenin Signaling Pathway

Cells (Basel, Switzerland), 2024-06, Vol.13 (11), p.986

2024

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Drosophila Apc1 and Apc2 regulate Wingless transduction throughout development

Development (Cambridge), 2002-04, Vol.129 (7), p.1751-1762

2002

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Regulation of Armadillo by a Drosophila APC Inhibits Neuronal Apoptosis during Retinal Development

Cell, 1998-06, Vol.93 (7), p.1171-1182

1998

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Nuclear Regulation of Wnt/β-Catenin Signaling: It's a Complex Situation

Genes, 2020-08, Vol.11 (8), p.886

2020

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Adenomatous polyposis coli is present near the minimal level required for accurate graded responses to the Wingless morphogen

Development (Cambridge), 2008-03, Vol.135 (5), p.963-971

2008

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The ADP-ribose polymerase Tankyrase regulates adult intestinal stem cell proliferation during homeostasis in Drosophila

Development (Cambridge), 2016-05, Vol.143 (10), p.1710-1720

2016

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Wnt/Wingless Pathway Activation Is Promoted by a Critical Threshold of Axin Maintained by the Tumor Suppressor APC and the ADP-Ribose Polymerase Tankyrase

Genetics (Austin), 2016-05, Vol.203 (1), p.269-281

2016

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APC Inhibits Ligand-Independent Wnt Signaling by the Clathrin Endocytic Pathway

Developmental cell, 2018-03, Vol.44 (5), p.566-581.e8

2018

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The Casein kinase 1α agonist pyrvinium attenuates Wnt-mediated CK1α degradation via interaction with the E3 ubiquitin ligase component Cereblon

The Journal of biological chemistry, 2022-08, Vol.298 (8), p.102227-102227, Article 102227

2022

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Single-Cell Analyses Confirm the Critical Role of LRP6 for Wnt Signaling in APC-Deficient Cells

Developmental cell, 2019-06, Vol.49 (6), p.827-828

2019

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Essential long-range action of Wingless/Wnt in adult intestinal compartmentalization

Regulation of Stem Cell Proliferation and Cell Fate Specification by Wingless/Wnt Signaling Gradients Enriched at Adult Intestinal Compartment Boundaries

The E3 ubiquitin ligase component, Cereblon, is an evolutionarily conserved regulator of Wnt signaling

Dual Roles for Membrane Association of Drosophila Axin in Wnt Signaling

G protein Gαi functions immediately downstream of Smoothened in Hedgehog signalling

Wnt pathway activation by ADP-ribosylation

Axin phosphorylation in both Wnt-off and Wnt-on states requires the tumor suppressor APC

Comparative genetic screens in human cells reveal new regulatory mechanisms in WNT signaling

Wingless/Wnt Signaling in Intestinal Development, Homeostasis, Regeneration and Tumorigenesis: A Drosophila Perspective

The USP46 deubiquitylase complex increases Wingless/Wnt signaling strength by stabilizing Arrow/LRP6

Casein Kinase 1α as a Regulator of Wnt-Driven Cancer

The USP46 complex deubiquitylates LRP6 to promote Wnt/β-catenin signaling

Intestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing

A Context-Dependent Role for the RNF146 Ubiquitin Ligase in Wingless/Wnt Signaling in Drosophila

Evidence for tankyrases as antineoplastic targets in lung cancer

Ileal Crohn's Disease Exhibits Reduced Activity of Phospholipase C-β3-Dependent Wnt/β-Catenin Signaling Pathway

Drosophila Apc1 and Apc2 regulate Wingless transduction throughout development

Regulation of Armadillo by a Drosophila APC Inhibits Neuronal Apoptosis during Retinal Development

Nuclear Regulation of Wnt/β-Catenin Signaling: It's a Complex Situation

Adenomatous polyposis coli is present near the minimal level required for accurate graded responses to the Wingless morphogen

The ADP-ribose polymerase Tankyrase regulates adult intestinal stem cell proliferation during homeostasis in Drosophila

Wnt/Wingless Pathway Activation Is Promoted by a Critical Threshold of Axin Maintained by the Tumor Suppressor APC and the ADP-Ribose Polymerase Tankyrase

APC Inhibits Ligand-Independent Wnt Signaling by the Clathrin Endocytic Pathway

The Casein kinase 1α agonist pyrvinium attenuates Wnt-mediated CK1α degradation via interaction with the E3 ubiquitin ligase component Cereblon

Single-Cell Analyses Confirm the Critical Role of LRP6 for Wnt Signaling in APC-Deficient Cells

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