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Regulating the regulator: post-translational modification of RAS

Nature reviews. Molecular cell biology, 2012-01, Vol.13 (1), p.39

2012

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Posttranslational Modifications of RAS Proteins

Cold Spring Harbor perspectives in medicine, 2018-11, Vol.8 (11), p.a031484

2018

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The structural features that distinguish PD-L2 from PD-L1 emerged in placental mammals

The Journal of biological chemistry, 2020-04, Vol.295 (14), p.4372-4380

2020

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KRAS4A directly regulates hexokinase 1

Nature (London), 2019-12, Vol.576 (7787), p.482-486

2019

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FKBP12 Binds to Acylated H-Ras and Promotes Depalmitoylation

Molecular cell, 2011-01, Vol.41 (2), p.173-185

2011

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A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells

eLife, 2021-02, Vol.10

2021

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Scaffold association factor B (SAFB) is required for expression of prenyltransferases and RAS membrane association

Proceedings of the National Academy of Sciences - PNAS, 2020-12, Vol.117 (50), p.31914-31922

2020

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Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division

The Journal of cell biology, 2008-05, Vol.181 (3), p.485-496

2008

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Palmitoylation and PDE6δ regulate membrane-compartment-specific substrate ubiquitylation and degradation

Cell reports (Cambridge), 2023-01, Vol.42 (1), p.111999-111999, Article 111999

2023

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PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis

Molecular cell, 2006-02, Vol.21 (4), p.481-493

2006

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Regulation of NOTCH signaling by RAB7 and RAB8 requires carboxyl methylation by ICMT

The Journal of cell biology, 2017-12, Vol.216 (12), p.4165-4182

2017

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Phospholipase Cγ activates Ras on the Golgi apparatus by means of RasGRP1

Nature (London), 2003-08, Vol.424 (6949), p.694-698

2003

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NRAS is unique among RAS proteins in requiring ICMT for trafficking to the plasma membrane

Life science alliance, 2021-05, Vol.4 (5), p.e202000972

2021

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Transmembrane domain-driven PD-1 dimers mediate T cell inhibition

Science immunology, 2024-03, Vol.9 (93), p.eade6256

2024

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Rap1 Up-Regulation and Activation on Plasma Membrane Regulates T Cell Adhesion

The Journal of cell biology, 2004-02, Vol.164 (3), p.461-470

2004

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Phospholipase D1 Regulates Lymphocyte Adhesion via Upregulation of Rap1 at the Plasma Membrane

Molecular and Cellular Biology, 2009-06, Vol.29 (12), p.3297-3306

2009

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Topology of Mammalian Isoprenylcysteine Carboxyl Methyltransferase Determined in Live Cells with a Fluorescent Probe

Molecular and Cellular Biology, 2009-04, Vol.29 (7), p.1826-1833

2009

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Linear atrophoderma of Moulin

Dermatology online journal, 2015-12, Vol.21 (12)

2015

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Primary cutaneous follicle-center lymphoma

Dermatology online journal, 2015, Vol.20 (12)

2015

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Metabolic labeling of Ras with tritiated palmitate to monitor palmitoylation and depalmitoylation

Methods in molecular biology (Clifton, N.J.), 2014, Vol.1120, p.33

2014

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VPS35 binds farnesylated N-Ras in the cytosol to regulate N-Ras trafficking

The Journal of cell biology, 2016-08, Vol.214 (4), p.445-458

2016

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Tache and talon noir in patient with mycosis fungoides on acitretin

Dermatology online journal, 2023-09, Vol.29 (4)

2023

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Single-Walled Carbon Nanotubes Deliver Peptide Antigen into Dendritic Cells and Enhance IgG Responses to Tumor-Associated Antigens

ACS nano, 2011-07, Vol.5 (7), p.5300-5311

2011

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Analysis of K‐Ras Phosphorylation, Translocation, and Induction of Apoptosis

Methods in Enzymology, 2008, Vol.439, p.87-102

2008

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Membrane trafficking of heterotrimeric G proteins via the endoplasmic reticulum and Golgi

Molecular biology of the cell, 2002-09, Vol.13 (9), p.3294-3302

2002

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Regulating the regulator: post-translational modification of RAS

Posttranslational Modifications of RAS Proteins

The structural features that distinguish PD-L2 from PD-L1 emerged in placental mammals

KRAS4A directly regulates hexokinase 1

FKBP12 Binds to Acylated H-Ras and Promotes Depalmitoylation

A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells

Scaffold association factor B (SAFB) is required for expression of prenyltransferases and RAS membrane association

Rac1 accumulates in the nucleus during the G2 phase of the cell cycle and promotes cell division

Palmitoylation and PDE6δ regulate membrane-compartment-specific substrate ubiquitylation and degradation

PKC regulates a farnesyl-electrostatic switch on K-Ras that promotes its association with Bcl-XL on mitochondria and induces apoptosis

Regulation of NOTCH signaling by RAB7 and RAB8 requires carboxyl methylation by ICMT

Phospholipase Cγ activates Ras on the Golgi apparatus by means of RasGRP1

NRAS is unique among RAS proteins in requiring ICMT for trafficking to the plasma membrane

Transmembrane domain-driven PD-1 dimers mediate T cell inhibition

Rap1 Up-Regulation and Activation on Plasma Membrane Regulates T Cell Adhesion

Phospholipase D1 Regulates Lymphocyte Adhesion via Upregulation of Rap1 at the Plasma Membrane

Topology of Mammalian Isoprenylcysteine Carboxyl Methyltransferase Determined in Live Cells with a Fluorescent Probe

Linear atrophoderma of Moulin

Primary cutaneous follicle-center lymphoma

Metabolic labeling of Ras with tritiated palmitate to monitor palmitoylation and depalmitoylation

VPS35 binds farnesylated N-Ras in the cytosol to regulate N-Ras trafficking

Tache and talon noir in patient with mycosis fungoides on acitretin

Single-Walled Carbon Nanotubes Deliver Peptide Antigen into Dendritic Cells and Enhance IgG Responses to Tumor-Associated Antigens

Analysis of K‐Ras Phosphorylation, Translocation, and Induction of Apoptosis

Membrane trafficking of heterotrimeric G proteins via the endoplasmic reticulum and Golgi

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