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Leveraging external data in the design and analysis of clinical trials in neuro-oncology

The lancet oncology, 2021-10, Vol.22 (10), p.e456-e465

2021

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Phase II multicenter study of gene-mediated cytotoxic immunotherapy as adjuvant to surgical resection for newly diagnosed malignant glioma

Neuro-oncology (Charlottesville, Va.), 2016-08, Vol.18 (8), p.1137-1145

2016

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Cytotoxic immunotherapy strategies for cancer: Mechanisms and clinical development

Journal of cellular biochemistry, 2011-08, Vol.112 (8), p.1969-1977

2011

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Preclinical investigation of combined gene-mediated cytotoxic immunotherapy and immune checkpoint blockade in glioblastoma

Neuro-oncology (Charlottesville, Va.), 2018-01, Vol.20 (2), p.225-235

2018

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Phase IB Study of Gene-Mediated Cytotoxic Immunotherapy Adjuvant to Up-Front Surgery and Intensive Timing Radiation for Malignant Glioma

Journal of clinical oncology, 2011-09, Vol.29 (27), p.3611-3619

2011

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Gene-mediated cytotoxic immunotherapy as adjuvant to surgery or chemoradiation for pancreatic adenocarcinoma

Cancer Immunology, Immunotherapy, 2015-06, Vol.64 (6), p.727-736

2015

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Systemic high-dose dexamethasone treatment may modulate the efficacy of intratumoral viral oncolytic immunotherapy in glioblastoma models

Journal for immunotherapy of cancer, 2022-01, Vol.10 (1), p.e003368

2022

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Phase I study of gene-mediated cytotoxic immunotherapy with AdV-tk as adjuvant to surgery and radiation for pediatric malignant glioma and recurrent ependymoma

Neuro-oncology (Charlottesville, Va.), 2019-03, Vol.21 (4), p.537-546

2019

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Neoadjuvant Gene-Mediated Cytotoxic Immunotherapy for Non-Small-Cell Lung Cancer: Safety and Immunologic Activity

Molecular therapy, 2021-02, Vol.29 (2), p.658-670

2021

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Therapeutic Endoscopic Ultrasonography: Intratumoral Injection for Pancreatic Adenocarcinoma

Gastroenterology research and practice, 2013-01, Vol.2013, p.207129-3

2013

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Phase I Study of Intrapleural Gene-Mediated Cytotoxic Immunotherapy in Patients with Malignant Pleural Effusion

Molecular therapy, 2018-05, Vol.26 (5), p.1198-1205

2018

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Impact of Preimmunization on Adenoviral Vector Expression and Toxicity in a Subcutaneous Mouse Cancer Model

Molecular therapy, 2002-09, Vol.6 (3), p.342-348

2002

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The Spectrum of Vaccine Therapies for Patients With Glioblastoma Multiforme

Current treatment options in oncology, 2012-12, Vol.13 (4), p.437-450

2012

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Abstract CT110: Phase II multicenter study of gene-mediated cytotoxic immunotherapy as an adjuvant to surgical resection for newly diagnosed malignant glioma: lessons learned from pseudo-progression and a nine-year survivor

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.CT110-CT110

2016

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The combination of adenoviral HSV TK gene therapy and radiation is effective in athymic mouse glioblastoma xenografts without increasing toxic side effects

Journal of neuro-oncology, 2004-03, Vol.67 (1-2), p.177-188

2004

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Liver Cirrhosis Is Reverted by Urokinase-Type Plasminogen Activator Gene Therapy

Molecular therapy, 2000-12, Vol.2 (6), p.545-551

2000

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Evolution of a gene therapy clinical trial. From bench to bedside and back

Journal of neuro-oncology, 2003-12, Vol.65 (3), p.307

2003

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Enhanced Therapeutic Effect of HSV-tk+GCV Gene Therapy and Ionizing Radiation for Prostate Cancer

Molecular therapy, 2001-04, Vol.3 (4), p.536-542

2001

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Evolution of a Gene Therapy Clinical Trial

Journal of neuro-oncology, 2003-12, Vol.65 (3), p.307-315

2003

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First report of safety/tolerability and preliminary antitumor activity of CAN-2409 in inadequate responders to immune checkpoint inhibitors for stage III/IV NSCLC

Journal of clinical oncology, 2022-06, Vol.40 (16_suppl), p.9037-9037

2022

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Neoadjuvant endobronchial delivery of gene mediated cytotoxic immunotherapy (GMCI) for non-small cell lung cancer (NSCLC): Safety and immunologic activity

Journal of clinical oncology, 2020-05, Vol.38 (15_suppl), p.9050-9050

2020

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First-in-human CAN-3110 (ICP-34.5 expressing HSV-1 oncolytic virus) in patients with recurrent high-grade glioma

Journal of clinical oncology, 2021-05, Vol.39 (15_suppl), p.2009-2009

2021

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CTIM-09. ENRICHED TCR/BCR VDJ REARRANGEMENTS CORRELATE WITH MRI AND SURVIVAL OUTCOMES IN PATIENTS WITH RECURRENT HIGH-GRADE GLIOMA TREATED WITH CAN-3110

Neuro-oncology (Charlottesville, Va.), 2022-11, Vol.24 (Supplement_7), p.vii61-vii61

2022

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Population based PSA screening in Mexico City

Journal of clinical oncology, 2017-02, Vol.35 (6_suppl), p.92-92

2017

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Intraprostatic distribution and long-term follow-up after AdV-tk immunotherapy as neoadjuvant to surgery in patients with prostate cancer

Cancer gene therapy, 2013-11, Vol.20 (11), p.642-649

2013

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Leveraging external data in the design and analysis of clinical trials in neuro-oncology

Phase II multicenter study of gene-mediated cytotoxic immunotherapy as adjuvant to surgical resection for newly diagnosed malignant glioma

Cytotoxic immunotherapy strategies for cancer: Mechanisms and clinical development

Preclinical investigation of combined gene-mediated cytotoxic immunotherapy and immune checkpoint blockade in glioblastoma

Phase IB Study of Gene-Mediated Cytotoxic Immunotherapy Adjuvant to Up-Front Surgery and Intensive Timing Radiation for Malignant Glioma

Gene-mediated cytotoxic immunotherapy as adjuvant to surgery or chemoradiation for pancreatic adenocarcinoma

Systemic high-dose dexamethasone treatment may modulate the efficacy of intratumoral viral oncolytic immunotherapy in glioblastoma models

Phase I study of gene-mediated cytotoxic immunotherapy with AdV-tk as adjuvant to surgery and radiation for pediatric malignant glioma and recurrent ependymoma

Neoadjuvant Gene-Mediated Cytotoxic Immunotherapy for Non-Small-Cell Lung Cancer: Safety and Immunologic Activity

Therapeutic Endoscopic Ultrasonography: Intratumoral Injection for Pancreatic Adenocarcinoma

Phase I Study of Intrapleural Gene-Mediated Cytotoxic Immunotherapy in Patients with Malignant Pleural Effusion

Impact of Preimmunization on Adenoviral Vector Expression and Toxicity in a Subcutaneous Mouse Cancer Model

The Spectrum of Vaccine Therapies for Patients With Glioblastoma Multiforme

Abstract CT110: Phase II multicenter study of gene-mediated cytotoxic immunotherapy as an adjuvant to surgical resection for newly diagnosed malignant glioma: lessons learned from pseudo-progression and a nine-year survivor

The combination of adenoviral HSV TK gene therapy and radiation is effective in athymic mouse glioblastoma xenografts without increasing toxic side effects

Liver Cirrhosis Is Reverted by Urokinase-Type Plasminogen Activator Gene Therapy

Evolution of a gene therapy clinical trial. From bench to bedside and back

Enhanced Therapeutic Effect of HSV-tk+GCV Gene Therapy and Ionizing Radiation for Prostate Cancer

Evolution of a Gene Therapy Clinical Trial

First report of safety/tolerability and preliminary antitumor activity of CAN-2409 in inadequate responders to immune checkpoint inhibitors for stage III/IV NSCLC

Neoadjuvant endobronchial delivery of gene mediated cytotoxic immunotherapy (GMCI) for non-small cell lung cancer (NSCLC): Safety and immunologic activity

First-in-human CAN-3110 (ICP-34.5 expressing HSV-1 oncolytic virus) in patients with recurrent high-grade glioma

CTIM-09. ENRICHED TCR/BCR VDJ REARRANGEMENTS CORRELATE WITH MRI AND SURVIVAL OUTCOMES IN PATIENTS WITH RECURRENT HIGH-GRADE GLIOMA TREATED WITH CAN-3110

Population based PSA screening in Mexico City

Intraprostatic distribution and long-term follow-up after AdV-tk immunotherapy as neoadjuvant to surgery in patients with prostate cancer

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