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ASCL1 activates neuronal stem cell-like lineage programming through remodeling of the chromatin landscape in prostate cancer

Nature communications, 2022-04, Vol.13 (1), p.2282-2282, Article 2282

2022

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Structural basis of collagen fiber degradation by cathepsin K

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (49), p.17474-17479

2014

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Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models

The Journal of clinical investigation, 2020-02, Vol.130 (2), p.699-714

2020

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A composite docking approach for the identification and characterization of ectosteric inhibitors of cathepsin K

PloS one, 2017-10, Vol.12 (10), p.e0186869-e0186869

2017

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Structural characterization of a capping protein interaction motif defines a family of actin filament regulators

Nature structural & molecular biology, 2010-04, Vol.17 (4), p.497-503

2010

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Identification of mouse cathepsin K structural elements that regulate the potency of odanacatib

Biochemical journal, 2017-03, Vol.474 (5), p.851-864

2017

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Identification of polyketide inhibitors targeting 3-dehydroquinate dehydratase in the shikimate pathway of Enterococcus faecalis

PloS one, 2014-07, Vol.9 (7), p.e103598-e103598

2014

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Structural basis of actin sequestration by thymosin-β4: implications for WH2 proteins

The EMBO journal, 2004-09, Vol.23 (18), p.3599-3608

2004

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Affinity Crystallography: A New Approach to Extracting High-Affinity Enzyme Inhibitors from Natural Extracts

Journal of natural products (Washington, D.C.), 2016-08, Vol.79 (8), p.1962-1970

2016

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Crystal structures of Vibrio harveyi chitinase A complexed with chitooligosaccharides: Implications for the catalytic mechanism

Journal of structural biology, 2008-06, Vol.162 (3), p.491-499

2008

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Potent Human α‑Amylase Inhibition by the β‑Defensin-like Protein Helianthamide

ACS central science, 2016-03, Vol.2 (3), p.154-161

2016

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The Structural Basis of Actin Interaction with Multiple WH2/β-Thymosin Motif-Containing Proteins

Structure (London), 2006-03, Vol.14 (3), p.469-476

2006

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The state of the filament

EMBO reports, 2005-03, Vol.6 (3), p.220-226

2005

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Abstract 14: Computer-aided discovery of small-molecule inhibitors targeting neural transcription factor BRN2 in neuroendocrine prostate tumors

Clinical cancer research, 2020-06, Vol.26 (12_Supplement_1), p.14-14

2020

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Abstract 3083: Selective inhibition of transcription factor BRN2 as a treatment strategy for Small Cell Prostate Cancer

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.3083-3083

2020

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Abstract 1295: First-in-field small molecule inhibitors targeting BRN2 as a therapeutic strategy for small cell prostate cancer

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.1295-1295

2019

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First-in-field small molecule inhibitors targeting BRN2 as a therapeutic strategy for small cell prostate cancer

Journal of clinical oncology, 2019-03, Vol.37 (7_suppl), p.260-260

2019

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The structure of the Mycobacterium smegmatis trehalose synthase reveals an unusual active site configuration and acarbose-binding mode

Glycobiology (Oxford), 2013-09, Vol.23 (9), p.1075-1083

2013

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Mycobacterial Trehalose Synthase as a potential drug target for tuberculosis

Acta crystallographica. Section A, Foundations and advances, 2014-08, Vol.70 (a1), p.C441-C441

2014

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The structure of the Mycobacterium smegmatis trehalose synthase reveals an unusual active site configuration and acarbose-binding mode super()

Glycobiology (Oxford), 2013-09, Vol.23 (9), p.1075-1083

2013

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Studies of Heat shock protein 27 Interactions

Acta crystallographica. Section A, Foundations and advances, 2014-08, Vol.70 (a1), p.C804-C804

2014

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Models of the Actin-Bound Forms of the β-Thymosins

Annals of the New York Academy of Sciences, 2007-09, Vol.1112 (1), p.56-66

2007

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Identification of Polyketide Inhibitors Targeting 3-Dehydroquinate Dehydratase in the Shikimate Pathway of Enterococcus faecalis: e103598

PloS one, 2014-07, Vol.9 (7)

2014

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Structural basis of actin sequestration by thymosin-[beta]4: implications for WH2 proteins

The EMBO journal, 2004-09, Vol.23 (18), p.3599

2004

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Structural basis of actin sequestration by thymosin-beta4: implications for WH2 proteins

The EMBO journal, 2004-09, Vol.23 (18), p.3599-3608

2004

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ASCL1 activates neuronal stem cell-like lineage programming through remodeling of the chromatin landscape in prostate cancer

Structural basis of collagen fiber degradation by cathepsin K

Ivermectin inhibits HSP27 and potentiates efficacy of oncogene targeting in tumor models

A composite docking approach for the identification and characterization of ectosteric inhibitors of cathepsin K

Structural characterization of a capping protein interaction motif defines a family of actin filament regulators

Identification of mouse cathepsin K structural elements that regulate the potency of odanacatib

Identification of polyketide inhibitors targeting 3-dehydroquinate dehydratase in the shikimate pathway of Enterococcus faecalis

Structural basis of actin sequestration by thymosin-β4: implications for WH2 proteins

Affinity Crystallography: A New Approach to Extracting High-Affinity Enzyme Inhibitors from Natural Extracts

Crystal structures of Vibrio harveyi chitinase A complexed with chitooligosaccharides: Implications for the catalytic mechanism

Potent Human α‑Amylase Inhibition by the β‑Defensin-like Protein Helianthamide

The Structural Basis of Actin Interaction with Multiple WH2/β-Thymosin Motif-Containing Proteins

The state of the filament

Abstract 14: Computer-aided discovery of small-molecule inhibitors targeting neural transcription factor BRN2 in neuroendocrine prostate tumors

Abstract 3083: Selective inhibition of transcription factor BRN2 as a treatment strategy for Small Cell Prostate Cancer

Abstract 1295: First-in-field small molecule inhibitors targeting BRN2 as a therapeutic strategy for small cell prostate cancer

First-in-field small molecule inhibitors targeting BRN2 as a therapeutic strategy for small cell prostate cancer

The structure of the Mycobacterium smegmatis trehalose synthase reveals an unusual active site configuration and acarbose-binding mode

Mycobacterial Trehalose Synthase as a potential drug target for tuberculosis

The structure of the Mycobacterium smegmatis trehalose synthase reveals an unusual active site configuration and acarbose-binding mode super()

Studies of Heat shock protein 27 Interactions

Models of the Actin-Bound Forms of the β-Thymosins

Identification of Polyketide Inhibitors Targeting 3-Dehydroquinate Dehydratase in the Shikimate Pathway of Enterococcus faecalis: e103598

Structural basis of actin sequestration by thymosin-[beta]4: implications for WH2 proteins

Structural basis of actin sequestration by thymosin-beta4: implications for WH2 proteins

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