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Peak learning of mass spectrometry imaging data using artificial neural networks

Nature communications, 2021-09, Vol.12 (1), p.5544-5544, Article 5544

2021

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Localized Metabolomic Gradients in Patient-Derived Xenograft Models of Glioblastoma

Cancer research (Chicago, Ill.), 2020-03, Vol.80 (6), p.1258-1267

2020

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Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS

Nature neuroscience, 2010-11, Vol.13 (11), p.1396-1403

2010

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Automatic 3D Nonlinear Registration of Mass Spectrometry Imaging and Magnetic Resonance Imaging Data

Analytical chemistry (Washington), 2019-05, Vol.91 (9), p.6206-6216

2019

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Protein aggregation and protein instability govern familial amyotrophic lateral sclerosis patient survival

PLoS biology, 2008-07, Vol.6 (7), p.e170-e170

2008

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Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma

Nature communications, 2018-11, Vol.9 (1), p.4904-13, Article 4904

2018

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Rapid discrimination of pediatric brain tumors by mass spectrometry imaging

Journal of neuro-oncology, 2018-11, Vol.140 (2), p.269-279

2018

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soluble α-synuclein construct forms a dynamic tetramer

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (43), p.17797-17802

2011

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A cutaneous lymphoma international prognostic index (CLIPi) for mycosis fungoides and Sezary syndrome

European journal of cancer (1990), 2013-09, Vol.49 (13), p.2859-2868

2013

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In Vitro Liquid Extraction Surface Analysis Mass Spectrometry (ivLESA-MS) for Direct Metabolic Analysis of Adherent Cells in Culture

Analytical chemistry (Washington), 2018-04, Vol.90 (8), p.4987-4991

2018

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The Human Proteoform Project: Defining the human proteome

Science advances, 2021-11, Vol.7 (46), p.eabk0734-eabk0734

2021

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Parsing disease‐relevant protein modifications from epiphenomena: perspective on the structural basis of SOD1‐mediated ALS

Journal of mass spectrometry., 2017-07, Vol.52 (7), p.480-491

2017

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Fitting Neurological Protein Aggregation Kinetic Data via a 2-Step, Minimal/“Ockham's Razor” Model: The Finke−Watzky Mechanism of Nucleation Followed by Autocatalytic Surface Growth

Biochemistry (Easton), 2008-02, Vol.47 (8), p.2413-2427

2008

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Nucleophilic substitution reactions of cyclic thiosulfinates are accelerated by hyperconjugative interactions

Chemical science (Cambridge), 2019-05, Vol.1 (21), p.5568-5575

2019

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Inhibition of medulloblastoma cell invasion by Slit

Oncogene, 2006-08, Vol.25 (37), p.5103-5112

2006

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IscU as a Scaffold for Iron−Sulfur Cluster Biosynthesis: Sequential Assembly of [2Fe-2S] and [4Fe-4S] Clusters in IscU

Biochemistry (Easton), 2000-07, Vol.39 (27), p.7856-7862

2000

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Strategies for stabilizing superoxide dismutase (SOD1), the protein destabilized in the most common form of familial amyotrophic lateral sclerosis

Proceedings of the National Academy of Sciences - PNAS, 2010-12, Vol.107 (50), p.21394-21399

2010

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Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS

PLoS biology, 2024-01, Vol.22 (1), p.e3002462, Article e3002462

2024

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Multiplatform Metabolomics Studies of Human Cancers With NMR and Mass Spectrometry Imaging

Frontiers in molecular biosciences, 2022-04, Vol.9, p.785232-785232

2022

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Sulfur Transfer from IscS to IscU: The First Step in Iron−Sulfur Cluster Biosynthesis

Journal of the American Chemical Society, 2001-11, Vol.123 (44), p.11103-11104

2001

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NifS-Directed Assembly of a Transient [2Fe-2S] Cluster within the NifU Protein

Proceedings of the National Academy of Sciences - PNAS, 2000-01, Vol.97 (2), p.599-604

2000

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Sensitive and Specific Identification of Wild Type and Variant Proteins from 8 to 669 kDa Using Top-down Mass Spectrometry

Molecular & cellular proteomics, 2009-04, Vol.8 (4), p.846-856

2009

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NifS-Mediated Assembly of [4Fe−4S] Clusters in the N- and C-Terminal Domains of the NifU Scaffold Protein

Biochemistry (Easton), 2005-10, Vol.44 (39), p.12955-12969

2005

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The Basal Layer in Human Squamous Tumors Harbors More UVA Than UVB Fingerprint Mutations: A Role for UVA in Human Skin Carcinogenesis

Proceedings of the National Academy of Sciences - PNAS, 2004-04, Vol.101 (14), p.4954-4959

2004

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massNet: integrated processing and classification of spatially resolved mass spectrometry data using deep learning for rapid tumor delineation

Bioinformatics, 2022-03, Vol.38 (7), p.2015-2021

2022

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Peak learning of mass spectrometry imaging data using artificial neural networks

Localized Metabolomic Gradients in Patient-Derived Xenograft Models of Glioblastoma

Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS

Automatic 3D Nonlinear Registration of Mass Spectrometry Imaging and Magnetic Resonance Imaging Data

Protein aggregation and protein instability govern familial amyotrophic lateral sclerosis patient survival

Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma

Rapid discrimination of pediatric brain tumors by mass spectrometry imaging

soluble α-synuclein construct forms a dynamic tetramer

A cutaneous lymphoma international prognostic index (CLIPi) for mycosis fungoides and Sezary syndrome

In Vitro Liquid Extraction Surface Analysis Mass Spectrometry (ivLESA-MS) for Direct Metabolic Analysis of Adherent Cells in Culture

The Human Proteoform Project: Defining the human proteome

Parsing disease‐relevant protein modifications from epiphenomena: perspective on the structural basis of SOD1‐mediated ALS

Fitting Neurological Protein Aggregation Kinetic Data via a 2-Step, Minimal/“Ockham's Razor” Model: The Finke−Watzky Mechanism of Nucleation Followed by Autocatalytic Surface Growth

Nucleophilic substitution reactions of cyclic thiosulfinates are accelerated by hyperconjugative interactions

Inhibition of medulloblastoma cell invasion by Slit

IscU as a Scaffold for Iron−Sulfur Cluster Biosynthesis: Sequential Assembly of [2Fe-2S] and [4Fe-4S] Clusters in IscU

Strategies for stabilizing superoxide dismutase (SOD1), the protein destabilized in the most common form of familial amyotrophic lateral sclerosis

Evaluating protein cross-linking as a therapeutic strategy to stabilize SOD1 variants in a mouse model of familial ALS

Multiplatform Metabolomics Studies of Human Cancers With NMR and Mass Spectrometry Imaging

Sulfur Transfer from IscS to IscU: The First Step in Iron−Sulfur Cluster Biosynthesis

NifS-Directed Assembly of a Transient [2Fe-2S] Cluster within the NifU Protein

Sensitive and Specific Identification of Wild Type and Variant Proteins from 8 to 669 kDa Using Top-down Mass Spectrometry

NifS-Mediated Assembly of [4Fe−4S] Clusters in the N- and C-Terminal Domains of the NifU Scaffold Protein

The Basal Layer in Human Squamous Tumors Harbors More UVA Than UVB Fingerprint Mutations: A Role for UVA in Human Skin Carcinogenesis

massNet: integrated processing and classification of spatially resolved mass spectrometry data using deep learning for rapid tumor delineation

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