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The Complicated Relationship between Gaucher Disease and Parkinsonism: Insights from a Rare Disease

Neuron (Cambridge, Mass.), 2017-02, Vol.93 (4), p.737-746

2017

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A characterization of Gaucher iPS-derived astrocytes: Potential implications for Parkinson's disease

Neurobiology of disease, 2020-02, Vol.134, p.104647-104647, Article 104647

2020

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GPR110 ligands reduce chronic optic tract gliosis and visual deficit following repetitive mild traumatic brain injury in mice

Journal of neuroinflammation, 2021-07, Vol.18 (1), p.157-157, Article 157

2021

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Macrophage models of Gaucher disease for evaluating disease pathogenesis and candidate drugs

Science translational medicine, 2014-06, Vol.6 (240), p.240ra73

2014

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GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils

Cell research, 2011-10, Vol.21 (10), p.1452-1469

2011

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Validation of anti-glucocerebrosidase antibodies for western blot analysis on protein lysates of murine and human cells

Biochemical journal, 2019-01, Vol.476 (2), p.261-274

2019

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Induced pluripotent stem cell models of lysosomal storage disorders

Disease models & mechanisms, 2017-06, Vol.10 (6), p.691-704

2017

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Chaperoning glucocerebrosidase： a therapeutic strategy for both Gaucher disease and Parkinsonism

Neural regeneration research, 2016-11, Vol.11 (11), p.1760-1761

2016

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Efferocytosis is impaired in Gaucher macrophages

Haematologica (Roma), 2017-04, Vol.102 (4), p.656

2017

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The role of human iPS-derived microglia-like cells in Gaucher and Parkinson disease

Molecular genetics and metabolism, 2019-02, Vol.126 (2), p.S20-S20

Aflaki, Elma

2019

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Toxicity of oxidized phospholipids in cultured macrophages

Lipids in health and disease, 2012-09, Vol.11 (1), p.110-110, Article 110

2012

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Triacylglycerol Accumulation Activates the Mitochondrial Apoptosis Pathway in Macrophages

The Journal of biological chemistry, 2011-03, Vol.286 (9), p.7418-7428

2011

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A new glucocerebrosidase-deficient neuronal cell model provides a tool to probe pathophysiology and therapeutics for Gaucher disease

Disease models & mechanisms, 2016-07, Vol.9 (7), p.769-778

2016

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Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice

Arteriosclerosis, thrombosis, and vascular biology, 2011-01, Vol.31 (1), p.67

2011

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The importance of astrocytes in the pathophysiology of GBA1-associated Parkinson disease

Molecular genetics and metabolism, 2018-02, Vol.123 (2), p.S93-S93

2018

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A New Glucocerebrosidase Chaperone Reduces α-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism

The Journal of neuroscience, 2016-07, Vol.36 (28), p.7441-7452

2016

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Lysosomal storage and impaired autophagy lead to inflammasome activation in Gaucher macrophages

Aging cell, 2016-02, Vol.15 (1), p.77-88

2016

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Dopamine-Related Measurements From Both IPSC-Derived Dopaminergic Neurons and [18F]-FDOPA PET in Patients With Gaucher Disease With and Without Parkinsonism

Biological psychiatry (1969), 2020-05, Vol.87 (9), p.S164

2020

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A characterization of Gaucher iPS-derived astrocytes: Potential implications for Parkinson disease

Neurobiology of disease, 2019-11, Vol.134, p.104647-104647

2019

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Adipose triglyceride lipase in immune response, inflammation, and atherosclerosis

Biological chemistry, 2012-09, Vol.393 (9), p.1005-1011

2012

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Degradation of Photoreceptor Outer Segments by the Retinal Pigment Epithelium Requires Pigment Epithelium-Derived Factor Receptor (PEDF-R)

Investigative ophthalmology & visual science, 2021-02, Vol.62 (2), p.30-30

2021

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Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase

The Journal of biological chemistry, 2010-06, Vol.285 (26), p.20192-20201

2010

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Mouse macrophage model of Gaucher disease for evaluating non-inhibitory chaperone candidates

Molecular genetics and metabolism, 2018-02, Vol.123 (2), p.S49-S49

2018

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Impaired phagosome maturation in Gaucher macrophages provides a new target for therapeutic intervention target

Molecular genetics and metabolism, 2017-01, Vol.120 (1-2), p.S94-S94

2017

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Patient-derived Gaucher induced pluripotent stem cells as a tool to understand common complex disorders

Molecular genetics and metabolism, 2018-02, Vol.123 (2), p.S128-S128

2018

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The Complicated Relationship between Gaucher Disease and Parkinsonism: Insights from a Rare Disease

A characterization of Gaucher iPS-derived astrocytes: Potential implications for Parkinson's disease

GPR110 ligands reduce chronic optic tract gliosis and visual deficit following repetitive mild traumatic brain injury in mice

Macrophage models of Gaucher disease for evaluating disease pathogenesis and candidate drugs

GPR55 regulates cannabinoid 2 receptor-mediated responses in human neutrophils

Validation of anti-glucocerebrosidase antibodies for western blot analysis on protein lysates of murine and human cells

Induced pluripotent stem cell models of lysosomal storage disorders

Chaperoning glucocerebrosidase： a therapeutic strategy for both Gaucher disease and Parkinsonism

Efferocytosis is impaired in Gaucher macrophages

The role of human iPS-derived microglia-like cells in Gaucher and Parkinson disease

Toxicity of oxidized phospholipids in cultured macrophages

Triacylglycerol Accumulation Activates the Mitochondrial Apoptosis Pathway in Macrophages

A new glucocerebrosidase-deficient neuronal cell model provides a tool to probe pathophysiology and therapeutics for Gaucher disease

Macrophage adipose triglyceride lipase deficiency attenuates atherosclerotic lesion development in low-density lipoprotein receptor knockout mice

The importance of astrocytes in the pathophysiology of GBA1-associated Parkinson disease

A New Glucocerebrosidase Chaperone Reduces α-Synuclein and Glycolipid Levels in iPSC-Derived Dopaminergic Neurons from Patients with Gaucher Disease and Parkinsonism

Lysosomal storage and impaired autophagy lead to inflammasome activation in Gaucher macrophages

Dopamine-Related Measurements From Both IPSC-Derived Dopaminergic Neurons and [18F]-FDOPA PET in Patients With Gaucher Disease With and Without Parkinsonism

A characterization of Gaucher iPS-derived astrocytes: Potential implications for Parkinson disease

Adipose triglyceride lipase in immune response, inflammation, and atherosclerosis

Degradation of Photoreceptor Outer Segments by the Retinal Pigment Epithelium Requires Pigment Epithelium-Derived Factor Receptor (PEDF-R)

Efficient Phagocytosis Requires Triacylglycerol Hydrolysis by Adipose Triglyceride Lipase

Mouse macrophage model of Gaucher disease for evaluating non-inhibitory chaperone candidates

Impaired phagosome maturation in Gaucher macrophages provides a new target for therapeutic intervention target

Patient-derived Gaucher induced pluripotent stem cells as a tool to understand common complex disorders

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