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Monomethyl auristatin antibody and peptide drug conjugates for trimodal cancer chemo-radio-immunotherapy

Nature communications, 2022-07, Vol.13 (1), p.1-16, Article 3869

2022

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A FZD7-specific Antibody-Drug Conjugate Induces Ovarian Tumor Regression in Preclinical Models

Molecular cancer therapeutics, 2022-01, Vol.21 (1), p.113-124

2022

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MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment

Nature communications, 2016-11, Vol.7 (1), p.13597-13597, Article 13597

2016

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Anti-tubulin drugs conjugated to anti-ErbB antibodies selectively radiosensitize

Nature communications, 2016-10, Vol.7 (1), p.13019-13019, Article 13019

2016

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Tumor Activated Cell Penetrating Peptides to Selectively Deliver Immune Modulatory Drugs

Pharmaceutics, 2021-03, Vol.13 (3), p.365

2021

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Phase I Trial of Intravenous Oncolytic Vaccinia Virus (GL-ONC1) with Cisplatin and Radiotherapy in Patients with Locoregionally Advanced Head and Neck Carcinoma

Clinical cancer research, 2017-10, Vol.23 (19), p.5696-5702

2017

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ReVOLT: radiation-enhanced viral oncolytic therapy

International journal of radiation oncology, biology, physics, 2006-11, Vol.66 (3), p.637-646

2006

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Establishment of Patient-Derived Succinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumor Models for Predicting Therapeutic Response

Clinical cancer research, 2022-01, Vol.28 (1), p.187-200

2022

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The Carboxyl-Terminal Domain of RNA Polymerase II Is Phosphorylated by a Complex Containing cdk9 and Infected-Cell Protein 22 of Herpes Simplex Virus 1

Journal of Virology, 2005-06, Vol.79 (11), p.6757-6762

2005

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Precision Chemoradiotherapy for HER2 Tumors Using Antibody Conjugates of an Auristatin Derivative with Reduced Cell Permeability

Molecular cancer therapeutics, 2020-01, Vol.19 (1), p.157-167

2020

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Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery

Cancer research (Chicago, Ill.), 2015-04, Vol.75 (7), p.1376-1387

2015

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Kinase-independent role for CRAF-driving tumour radioresistance via CHK2

Nature communications, 2015-09, Vol.6 (1), p.8154-8154, Article 8154

2015

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Redirecting extracellular proteases to molecularly guide radiosensitizing drugs to tumors

Biomaterials, 2020-07, Vol.248, p.120032-120032, Article 120032

2020

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Enhancing Radiotherapy With Genetically Engineered Viruses

Journal of clinical oncology, 2007-09, Vol.25 (26), p.4090-4095

2007

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Herpes Simplex Virus 1 Activates cdc2 to Recruit Topoisomerase IIα for Post-DNA Synthesis Expression of Late Genes

Proceedings of the National Academy of Sciences - PNAS, 2003-04, Vol.100 (8), p.4825-4830

2003

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Radiation-Drug Combinations to Improve Clinical Outcomes and Reduce Normal Tissue Toxicities: Current Challenges and New Approaches: Report of the Symposium Held at the 63rd Annual Meeting of the Radiation Research Society, 15-18 October 2017; Cancun, Mexico

Radiation research, 2018-10, Vol.190 (4), p.350

2018

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A MEK-independent role for CRAF in mitosis and tumor progression

Nature medicine, 2011-12, Vol.17 (12), p.1641-1645

2011

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An in vitro study for the dosimetric and radiobiological validation of respiratory gating in conventional and hypofractionated radiotherapy of the lung: effect of dose, dose rate, and breathing pattern

Physics in medicine & biology, 2019-07, Vol.64 (13), p.135009-135009

2019

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The Role of cdc2 in the Expression of Herpes Simplex Virus Genes

Proceedings of the National Academy of Sciences - PNAS, 2000-09, Vol.97 (20), p.10996-11001

2000

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Preferential Replication of Systemically Delivered Oncolytic Vaccinia Virus in Focally Irradiated Glioma Xenografts

Clinical cancer research, 2012-05, Vol.18 (9), p.2579-2590

2012

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Combination of fractionated irradiation with anti‐VEGF expressing vaccinia virus therapy enhances tumor control by simultaneous radiosensitization of tumor associated endothelium

International journal of cancer, 2013-12, Vol.133 (12), p.2989-2999

2013

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Abstract 977: RNA-sequencing analysis implicates novel non-coding RNAs in human papillomavirus-associated head and neck squamous cell carcinoma

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.977-977

2016

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Clinical and cosmetic outcomes in patients treated with high-dose-rate electronic brachytherapy for nonmelanoma skin cancer

Practical Radiation Oncology, 2015-11, Vol.5 (6), p.e659-e664

2015

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Combined TP53 mutation/3p loss correlates with decreased radiosensitivity and increased matrix-metalloproteinase activity in head and neck carcinoma

Oral oncology, 2015-05, Vol.51 (5), p.470-475

2015

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DNA damage response and repair: insights into strategies for radiation sensitization of gliomas

Future oncology (London, England), 2011-11, Vol.7 (11), p.1335-1346

2011

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Monomethyl auristatin antibody and peptide drug conjugates for trimodal cancer chemo-radio-immunotherapy

A FZD7-specific Antibody-Drug Conjugate Induces Ovarian Tumor Regression in Preclinical Models

MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment

Anti-tubulin drugs conjugated to anti-ErbB antibodies selectively radiosensitize

Tumor Activated Cell Penetrating Peptides to Selectively Deliver Immune Modulatory Drugs

Phase I Trial of Intravenous Oncolytic Vaccinia Virus (GL-ONC1) with Cisplatin and Radiotherapy in Patients with Locoregionally Advanced Head and Neck Carcinoma

ReVOLT: radiation-enhanced viral oncolytic therapy

Establishment of Patient-Derived Succinate Dehydrogenase-Deficient Gastrointestinal Stromal Tumor Models for Predicting Therapeutic Response

The Carboxyl-Terminal Domain of RNA Polymerase II Is Phosphorylated by a Complex Containing cdk9 and Infected-Cell Protein 22 of Herpes Simplex Virus 1

Precision Chemoradiotherapy for HER2 Tumors Using Antibody Conjugates of an Auristatin Derivative with Reduced Cell Permeability

Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery

Kinase-independent role for CRAF-driving tumour radioresistance via CHK2

Redirecting extracellular proteases to molecularly guide radiosensitizing drugs to tumors

Enhancing Radiotherapy With Genetically Engineered Viruses

Herpes Simplex Virus 1 Activates cdc2 to Recruit Topoisomerase IIα for Post-DNA Synthesis Expression of Late Genes

Radiation-Drug Combinations to Improve Clinical Outcomes and Reduce Normal Tissue Toxicities: Current Challenges and New Approaches: Report of the Symposium Held at the 63rd Annual Meeting of the Radiation Research Society, 15-18 October 2017; Cancun, Mexico

A MEK-independent role for CRAF in mitosis and tumor progression

An in vitro study for the dosimetric and radiobiological validation of respiratory gating in conventional and hypofractionated radiotherapy of the lung: effect of dose, dose rate, and breathing pattern

The Role of cdc2 in the Expression of Herpes Simplex Virus Genes

Preferential Replication of Systemically Delivered Oncolytic Vaccinia Virus in Focally Irradiated Glioma Xenografts

Combination of fractionated irradiation with anti‐VEGF expressing vaccinia virus therapy enhances tumor control by simultaneous radiosensitization of tumor associated endothelium

Abstract 977: RNA-sequencing analysis implicates novel non-coding RNAs in human papillomavirus-associated head and neck squamous cell carcinoma

Clinical and cosmetic outcomes in patients treated with high-dose-rate electronic brachytherapy for nonmelanoma skin cancer

Combined TP53 mutation/3p loss correlates with decreased radiosensitivity and increased matrix-metalloproteinase activity in head and neck carcinoma

DNA damage response and repair: insights into strategies for radiation sensitization of gliomas

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