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Identification of novel regulators of STAT3 activity

PloS one, 2020-03, Vol.15 (3), p.e0230819-e0230819

2020

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Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia

The New England journal of medicine, 2012-05, Vol.366 (20), p.1905-1913

2012

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Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia

Blood, 2013-05, Vol.121 (22), p.4541-4550

2013

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MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1–regulated pathways in mice

Blood, 2011-07, Vol.118 (4), p.916-925

2011

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A report on the potential of Rac1/pSTAT3 protein levels in T lymphocytes to assess the pharmacodynamic effect of thiopurine therapy in Inflammatory Bowel Disease patients

Scientific reports, 2022-09, Vol.12 (1), p.15806-15806, Article 15806

2022

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High-Throughput Dual Screening Method for Ras Activities and Inhibitors

Analytical chemistry (Washington), 2017-04, Vol.89 (8), p.4508-4516

2017

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A homogeneous quenching resonance energy transfer assay for the kinetic analysis of the GTPase nucleotide exchange reaction

Analytical and bioanalytical chemistry, 2014-07, Vol.406 (17), p.4147-4156

2014

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Discovery of MINC1, a GTPase-activating protein small molecule inhibitor, targeting MgcRacGAP

Combinatorial chemistry & high throughput screening, 2015-01, Vol.18 (1), p.3-17

2015

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Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions

Cell chemical biology, 2018-02, Vol.25 (2), p.224-229.e2

2018

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MgcRacGAP inhibition stimulates JAK-dependent STAT3 activity

FEBS letters, 2015-12, Vol.589 (24), p.3859-3865

2015

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Hemocytometric characteristics of COVID-19 patients with and without cytokine storm syndrome on the sysmex XN-10 hematology analyzer

Clinical chemistry and laboratory medicine, 2021-03, Vol.59 (4), p.783-793

2021

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Rac1/pSTAT3 expression: A pharmacodynamic marker panel as a first step toward optimization of thiopurine therapy in inflammatory bowel disease patients

Cytometry. Part A, 2022-02, Vol.101 (2), p.167-176

2022

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Toward universal protein post-translational modification detection in high throughput format

Chemical communications (Cambridge, England), 2018, Vol.54 (23), p.2910-2913

2018

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Abstract 2991: Inhibition of Rac1 GTPase activity by SH7139, a new drug candidate for non-Hodgkin's lymphoma targeting HLA-DR10

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.2991-2991

2016

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Drug sensitivity profiling identifies potential therapies for lymphoproliferative disorders with overactive JAK/STAT3 signaling

Oncotarget, 2017-11, Vol.8 (57), p.97516-97527

2017

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Activating somatic mutations outside the SH2-domain of STAT3 in LGL leukemia

Leukemia, 2016-05, Vol.30 (5), p.1204-1208

2016

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Abstract 3343: Identifying kinases and phosphatases that regulate STAT3 activity

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.3343-3343

2018

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Toward universal protein post-translational modification detection in high throughput formatElectronic supplementary information (ESI) available: Table S1, Fig. S1-S3, materials and methods. See DOI: 10.1039/c7cc09575a

2018-03

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Drug Sensitivity Profiling Identifies Drugs for Targeting Constitutively Active Mutant STAT3 and Mutant STAT5B Positive Malignancies

Blood, 2014-12, Vol.124 (21), p.1771-1771

2014

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Abstract 606: Novel somatic mutations in the DNA-binding and coiled-coil domain of the STAT3 gene in LGL-leukemia

Cancer research (Chicago, Ill.), 2015-08, Vol.75 (15_Supplement), p.606-606

2015

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Wat we kunnen leren van het gebruik van datamining bij de correctie van de kaliumconcentratie in een hemolytisch monster?

Laboratoriumgeneeskunde, 2021-07, Vol.4 (3), p.7-7

2021

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Discovery of STAT5b Mutations and Small Subclones of STAT3 Mutations in Large Granular Lymphocytic (LGL) Leukemia

Blood, 2012-11, Vol.120 (21), p.871-871

2012

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Ontwikkeling diagnostische richtlijnmodules voor de klinische chemie

Laboratoriumgeneeskunde, 2024-09, Vol.7 (4)

2024

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Imaging of small vessels using photoacoustics: An in vivo study

Lasers in surgery and medicine, 2004-12, Vol.35 (5), p.354-362

2004

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Identification of novel regulators of STAT3 activity

Somatic STAT3 Mutations in Large Granular Lymphocytic Leukemia

Discovery of somatic STAT5b mutations in large granular lymphocytic leukemia

MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1–regulated pathways in mice

A report on the potential of Rac1/pSTAT3 protein levels in T lymphocytes to assess the pharmacodynamic effect of thiopurine therapy in Inflammatory Bowel Disease patients

High-Throughput Dual Screening Method for Ras Activities and Inhibitors

A homogeneous quenching resonance energy transfer assay for the kinetic analysis of the GTPase nucleotide exchange reaction

Discovery of MINC1, a GTPase-activating protein small molecule inhibitor, targeting MgcRacGAP

Autoimmunity, hypogammaglobulinemia, lymphoproliferation, and mycobacterial disease in patients with activating mutations in STAT3

Drug Target Commons: A Community Effort to Build a Consensus Knowledge Base for Drug-Target Interactions

MgcRacGAP inhibition stimulates JAK-dependent STAT3 activity

Hemocytometric characteristics of COVID-19 patients with and without cytokine storm syndrome on the sysmex XN-10 hematology analyzer

Rac1/pSTAT3 expression: A pharmacodynamic marker panel as a first step toward optimization of thiopurine therapy in inflammatory bowel disease patients

Toward universal protein post-translational modification detection in high throughput format

Abstract 2991: Inhibition of Rac1 GTPase activity by SH7139, a new drug candidate for non-Hodgkin's lymphoma targeting HLA-DR10

Drug sensitivity profiling identifies potential therapies for lymphoproliferative disorders with overactive JAK/STAT3 signaling

Activating somatic mutations outside the SH2-domain of STAT3 in LGL leukemia

Abstract 3343: Identifying kinases and phosphatases that regulate STAT3 activity

Toward universal protein post-translational modification detection in high throughput formatElectronic supplementary information (ESI) available: Table S1, Fig. S1-S3, materials and methods. See DOI: 10.1039/c7cc09575a

Drug Sensitivity Profiling Identifies Drugs for Targeting Constitutively Active Mutant STAT3 and Mutant STAT5B Positive Malignancies

Abstract 606: Novel somatic mutations in the DNA-binding and coiled-coil domain of the STAT3 gene in LGL-leukemia

Wat we kunnen leren van het gebruik van datamining bij de correctie van de kaliumconcentratie in een hemolytisch monster?

Discovery of STAT5b Mutations and Small Subclones of STAT3 Mutations in Large Granular Lymphocytic (LGL) Leukemia

Ontwikkeling diagnostische richtlijnmodules voor de klinische chemie

Imaging of small vessels using photoacoustics: An in vivo study

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