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Design and synthesis of pyrazole–oxindole conjugates targeting tubulin polymerization as new anticancer agents

European journal of medicinal chemistry, 2015-03, Vol.92, p.501-513

2015

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Structure of Aminopeptidase N from Escherichia coli Suggests a Compartmentalized, Gated Active Site

Proceedings of the National Academy of Sciences - PNAS, 2006-09, Vol.103 (36), p.13339-13344

2006

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Genomic characterization and evolutionary analysis of dengue virus from Aedes mosquitoes in Telangana, India

Journal of vector borne diseases, 2023-04, Vol.60 (2), p.179-186

2023

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Discovery of a new genetic variant of methionine aminopeptidase from Streptococci with possible post-translational modifications: biochemical and structural characterization

PloS one, 2013-10, Vol.8 (10), p.e75207-e75207

2013

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Development of peptidomimetic hydroxamates as PfA-M1 and PfA-M17 dual inhibitors: Biological evaluation and structural characterization by cocrystallization

Chinese chemical letters, 2022-05, Vol.33 (5), p.2550-2554

2022

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Aminobenzosuberone Scaffold as a Modular Chemical Tool for the Inhibition of Therapeutically Relevant M1 Aminopeptidases

Molecules (Basel, Switzerland), 2018-10, Vol.23 (10), p.2607

2018

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Structural Basis for the Unusual Specificity of Escherichia coli Aminopeptidase N

Biochemistry (Easton), 2008-05, Vol.47 (19), p.5303-5311

2008

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Gymnema sylvestre extract improves PCOS by altering the YAP1 protein in the mouse ovary via mitochondrial changes

Phytomedicine Plus : International journal of phytotherapy and phytopharmacology, 2024-02, Vol.4 (1), p.100515, Article 100515

2024

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Design, Synthesis and Mechanistic Studies of Novel Isatin-Pyrazole Hydrazone Conjugates as Selective and Potent Bacterial MetAP Inhibitors

Antibiotics (Basel), 2022-08, Vol.11 (8), p.1126

2022

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Structural Basis for the Functional Differences between Type I and Type II Human Methionine Aminopeptidases

Biochemistry (Easton), 2005-11, Vol.44 (45), p.14741-14749

2005

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Elucidation of the Function of Type 1 Human Methionine Aminopeptidase during Cell Cycle Progression

Proceedings of the National Academy of Sciences - PNAS, 2006-11, Vol.103 (48), p.18148-18153

2006

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A single amino acid difference between archaeal and human type 2 methionine aminopeptidases differentiates their affinity towards ovalicin

Biochimica et biophysica acta. Proteins and proteomics, 2023-02, Vol.1871 (2), p.140881-140881, Article 140881

2023

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Exo-selective intermolecular Diels-Alder reaction by PyrI4 and AbnU on non-natural substrates

Communications chemistry, 2021-08, Vol.4 (1), p.113-113, Article 113

2021

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Synthesis and Biological Evaluation of Imidazopyridine-Oxindole Conjugates as Microtubule-Targeting Agents

ChemMedChem, 2013-12, Vol.8 (12), p.2015-2025

2013

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Discovery of new genetic variants of methionine aminopeptidases

Acta crystallographica. Section A, Foundations and advances, 2017-12, Vol.73 (a2), p.C282-C282

2017

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Synthesis, cytotoxicity and hDHFR inhibition studies of 2H-pyrido[1,2-a]pyrimidin-2-ones

MedChemComm, 2013-05, Vol.4 (5), p.817

2013

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Evidence for Functional Role of C-H···S Hydrogen Bond in Enzyme Catalysis and Substrate Specificity: Type 1 Methionine Aminopeptidase

Biophysical journal, 2014-01, Vol.106 (2), p.676a-676a

2014

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Development of selective inhibitors against malarial M1 family aminopeptidase

Acta crystallographica. Section A, Foundations and advances, 2017-12, Vol.73 (a2), p.C237-C237

2017

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Understanding the structural basis of Legionella pneumophila aminopeptidase N

Acta crystallographica. Section A, Foundations and advances, 2017-12, Vol.73 (a2), p.C158-C158

2017

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Strategic enzymatic enantioselective desymmetrization of prochiral cyclohexa-2,5-dienones

Chemical communications (Cambridge, England), 2024-06, Vol.6 (52), p.6647-665

2024

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Methionine aminopeptidases with short sequence inserts within the catalytic domain are differentially inhibited: Structural and biochemical studies of three proteins from Vibrio spp

European journal of medicinal chemistry, 2021-01, Vol.209, p.112883-112883, Article 112883

2021

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Discovery of natural product ovalicin sensitive type 1 methionine aminopeptidases: molecular and structural basis

Biochemical journal, 2019-03, Vol.476 (6), p.991-1003

2019

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Development of 2-chloroquinoline based heterocyclic frameworks as dual inhibitors of SARS-CoV-2 MPro and PLPro

International journal of biological macromolecules, 2023-07, Vol.242, p.124772-124772, Article 124772

2023

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Unraveling structural insights of ribokinase from Leishmania donovani

International journal of biological macromolecules, 2019-09, Vol.136, p.253-265

2019

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Discovery of a new class of type 1 methionine aminopeptidases that have relaxed substrate specificity

International journal of biological macromolecules, 2019-05, Vol.129, p.523-529

2019

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Design and synthesis of pyrazole–oxindole conjugates targeting tubulin polymerization as new anticancer agents

Structure of Aminopeptidase N from Escherichia coli Suggests a Compartmentalized, Gated Active Site

Genomic characterization and evolutionary analysis of dengue virus from Aedes mosquitoes in Telangana, India

Discovery of a new genetic variant of methionine aminopeptidase from Streptococci with possible post-translational modifications: biochemical and structural characterization

Development of peptidomimetic hydroxamates as PfA-M1 and PfA-M17 dual inhibitors: Biological evaluation and structural characterization by cocrystallization

Aminobenzosuberone Scaffold as a Modular Chemical Tool for the Inhibition of Therapeutically Relevant M1 Aminopeptidases

Structural Basis for the Unusual Specificity of Escherichia coli Aminopeptidase N

Gymnema sylvestre extract improves PCOS by altering the YAP1 protein in the mouse ovary via mitochondrial changes

Design, Synthesis and Mechanistic Studies of Novel Isatin-Pyrazole Hydrazone Conjugates as Selective and Potent Bacterial MetAP Inhibitors

Structural Basis for the Functional Differences between Type I and Type II Human Methionine Aminopeptidases

Elucidation of the Function of Type 1 Human Methionine Aminopeptidase during Cell Cycle Progression

A single amino acid difference between archaeal and human type 2 methionine aminopeptidases differentiates their affinity towards ovalicin

Exo-selective intermolecular Diels-Alder reaction by PyrI4 and AbnU on non-natural substrates

Synthesis and Biological Evaluation of Imidazopyridine-Oxindole Conjugates as Microtubule-Targeting Agents

Discovery of new genetic variants of methionine aminopeptidases

Synthesis, cytotoxicity and hDHFR inhibition studies of 2H-pyrido[1,2-a]pyrimidin-2-ones

Evidence for Functional Role of C-H···S Hydrogen Bond in Enzyme Catalysis and Substrate Specificity: Type 1 Methionine Aminopeptidase

Development of selective inhibitors against malarial M1 family aminopeptidase

Understanding the structural basis of Legionella pneumophila aminopeptidase N

Strategic enzymatic enantioselective desymmetrization of prochiral cyclohexa-2,5-dienones

Methionine aminopeptidases with short sequence inserts within the catalytic domain are differentially inhibited: Structural and biochemical studies of three proteins from Vibrio spp

Discovery of natural product ovalicin sensitive type 1 methionine aminopeptidases: molecular and structural basis

Development of 2-chloroquinoline based heterocyclic frameworks as dual inhibitors of SARS-CoV-2 MPro and PLPro

Unraveling structural insights of ribokinase from Leishmania donovani

Discovery of a new class of type 1 methionine aminopeptidases that have relaxed substrate specificity

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