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EZH2 or HDAC1 Inhibition Reverses Multiple Myeloma-Induced Epigenetic Suppression of Osteoblast Differentiation

Molecular cancer research, 2017-04, Vol.15 (4), p.405-417

2017

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Distinct metabolic states guide maturation of inflammatory and tolerogenic dendritic cells

Nature communications, 2022-09, Vol.13 (1), p.5184-5184, Article 5184

2022

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Immuno-metabolic dendritic cell vaccine signatures associate with overall survival in vaccinated melanoma patients

Nature communications, 2023-11, Vol.14 (1), p.7211-7211, Article 7211

2023

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EZH2 Supports Osteoclast Differentiation and Bone Resorption Via Epigenetic and Cytoplasmic Targets

Journal of bone and mineral research, 2020-01, Vol.35 (1), p.181-195

2020

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The Role of Semaphorin 4D in Bone Remodeling and Cancer Metastasis

Frontiers in endocrinology (Lausanne), 2018-06, Vol.9, p.322-322

2018

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Cell trafficking and regulation of osteoblastogenesis by extracellular vesicle associated bone morphogenetic protein 2

Journal of extracellular vesicles, 2021-10, Vol.10 (12), p.e12155-n/a

2021

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667 Tumor-derived alpha-fetoprotein requires polyunsaturated fatty acids for immuno-metabolic dysregulation

Journal for immunotherapy of cancer, 2021-11, Vol.9 (Suppl 2), p.A695-A695

2021

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Osteoblast suppression in multiple myeloma bone disease

Journal of bone oncology, 2018-11, Vol.13, p.62-70

2018

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829 Tumor alpha-fetoprotein inhibits cholesterol and steroid metabolism in monocyte-derived dendritic cells

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A880-A881

2020

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Epigenetic-Based Mechanisms of Osteoblast Suppression in Multiple Myeloma Bone Disease

JBMR plus, 2019-03, Vol.3 (3), p.e10183-e10183

2019

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XRK3F2 Inhibition of p62-ZZ Domain Signaling Rescues Myeloma-Induced GFI1-Driven Epigenetic Repression of the Runx2 Gene in Pre-osteoblasts to Overcome Differentiation Suppression

Frontiers in endocrinology (Lausanne), 2018-06, Vol.9, p.344-344

2018

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704 Biological activity of FLX475, an oral CCR4 antagonist, as monotherapy and in combination with pembrolizumab in advanced cancer

Journal for immunotherapy of cancer, 2023-11, Vol.11 (Suppl 1), p.A799-A799

2023

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Distinct mechanisms for induction and tolerance regulate the immediate early genes encoding interleukin 1β and tumor necrosis factor α

PloS one, 2013-08, Vol.8 (8), p.e70622

2013

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299 Immuno-metabolic signatures of dendritic cells associate with T-cell responses in melanoma patients

Journal for immunotherapy of cancer, 2020-11, Vol.8 (Suppl 3), p.A326-A326

2020

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What's next for cancer vaccines

Science translational medicine, 2022-11, Vol.14 (670), p.eabo4632

2022

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Immunomodulatory impact of α-fetoprotein

Trends in immunology, 2022-06, Vol.43 (6), p.438-448

2022

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Distinct hypoxic molecular mechanisms differentially regulate human vs. mouse Interleukin 1β gene expression in monocytes/macrophages

The Journal of immunology (1950), 2023-05, Vol.210 (1_Supplement), p.167-167.33

2023

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Clinical and biological activity of FLX475, an oral CCR4 antagonist, in advanced cancer

Journal of clinical oncology, 2023-06, Vol.41 (16_suppl), p.2625-2625

2023

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Impact of checkpoint blockade on cancer vaccine-activated CD8+ T cell responses

The Journal of experimental medicine, 2020-07, Vol.217 (7)

2020

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Epigenetics of Multiple Myeloma Bone Disease

Current molecular biology reports, 2019-06, Vol.5 (2), p.86-96

2019

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Polyunsaturated Fatty Acid-Bound α-Fetoprotein Promotes Immune Suppression by Altering Human Dendritic Cell Metabolism

Cancer research (Chicago, Ill.), 2023-05, Vol.83 (9), p.1543-1557

2023

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Epigenetic Targeting of the Myeloma-Bone Microenvironment in 3D

Blood, 2018-11, Vol.132 (Supplement 1), p.246-246

2018

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Semaphorin 4D to suppress bone formation in multiple myeloma

Journal of clinical oncology, 2017-05, Vol.35 (15_suppl), p.8039-8039

2017

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Distinct Mechanisms Regulate IL1B and TNF Gene Expression

The FASEB journal, 2015-04, Vol.29 (S1)

2015

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Abstract 5070: Sulforaphane is a novel inhibitor of breast cancer-induced osteolytic bone resorption

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.5070-5070

2019

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EZH2 or HDAC1 Inhibition Reverses Multiple Myeloma-Induced Epigenetic Suppression of Osteoblast Differentiation

Distinct metabolic states guide maturation of inflammatory and tolerogenic dendritic cells

Immuno-metabolic dendritic cell vaccine signatures associate with overall survival in vaccinated melanoma patients

EZH2 Supports Osteoclast Differentiation and Bone Resorption Via Epigenetic and Cytoplasmic Targets

The Role of Semaphorin 4D in Bone Remodeling and Cancer Metastasis

Cell trafficking and regulation of osteoblastogenesis by extracellular vesicle associated bone morphogenetic protein 2

667 Tumor-derived alpha-fetoprotein requires polyunsaturated fatty acids for immuno-metabolic dysregulation

Osteoblast suppression in multiple myeloma bone disease

829 Tumor alpha-fetoprotein inhibits cholesterol and steroid metabolism in monocyte-derived dendritic cells

Epigenetic-Based Mechanisms of Osteoblast Suppression in Multiple Myeloma Bone Disease

XRK3F2 Inhibition of p62-ZZ Domain Signaling Rescues Myeloma-Induced GFI1-Driven Epigenetic Repression of the Runx2 Gene in Pre-osteoblasts to Overcome Differentiation Suppression

704 Biological activity of FLX475, an oral CCR4 antagonist, as monotherapy and in combination with pembrolizumab in advanced cancer

Distinct mechanisms for induction and tolerance regulate the immediate early genes encoding interleukin 1β and tumor necrosis factor α

299 Immuno-metabolic signatures of dendritic cells associate with T-cell responses in melanoma patients

What's next for cancer vaccines

Immunomodulatory impact of α-fetoprotein

Distinct hypoxic molecular mechanisms differentially regulate human vs. mouse Interleukin 1β gene expression in monocytes/macrophages

Clinical and biological activity of FLX475, an oral CCR4 antagonist, in advanced cancer

Impact of checkpoint blockade on cancer vaccine-activated CD8+ T cell responses

Epigenetics of Multiple Myeloma Bone Disease

Polyunsaturated Fatty Acid-Bound α-Fetoprotein Promotes Immune Suppression by Altering Human Dendritic Cell Metabolism

Epigenetic Targeting of the Myeloma-Bone Microenvironment in 3D

Semaphorin 4D to suppress bone formation in multiple myeloma

Distinct Mechanisms Regulate IL1B and TNF Gene Expression

Abstract 5070: Sulforaphane is a novel inhibitor of breast cancer-induced osteolytic bone resorption

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