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Targeting lymphangiogenesis to prevent tumour metastasis

British journal of cancer, 2006-05, Vol.94 (10), p.1355-1360

2006

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A phase Ib/II translational study of sunitinib with neoadjuvant radiotherapy in soft-tissue sarcoma

British journal of cancer, 2014-12, Vol.111 (12), p.2254-2261

2014

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Elevated level of inhibin-α subunit is pro-tumourigenic and pro-metastatic and associated with extracapsular spread in advanced prostate cancer

British journal of cancer, 2009-06, Vol.100 (11), p.1784-1793

2009

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Lymphangiogenesis and cancer metastasis

Nature reviews. Cancer, 2002-08, Vol.2 (8), p.573-583

2002

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Intestinal-specific activatable Myb initiates colon tumorigenesis in mice

Oncogene, 2016-05, Vol.35 (19), p.2475-2484

2016

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VEGF-D promotes the metastatic spread of tumor cells via the lymphatics

Nature medicine, 2001-02, Vol.7 (2), p.186-191

2001

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Gene transfer using the mature form of VEGF-D reduces neointimal thickening through nitric oxide-dependent mechanism

Gene therapy, 2005-06, Vol.12 (12), p.980-987

2005

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Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3

The EMBO journal, 2001-09, Vol.20 (17), p.4762-4773

2001

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VEGF-D Is the Strongest Angiogenic and Lymphangiogenic Effector Among VEGFs Delivered Into Skeletal Muscle via Adenoviruses

Circulation research, 2003-05, Vol.92 (10), p.1098-1106

2003

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Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice

The EMBO journal, 2001-03, Vol.20 (6), p.1223-1231

2001

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Vascular Endothelial Growth Factor D (VEGF-D) is a Ligand for the Tyrosine Kinases VEGF Receptor 2 (Flk1) and VEGF Receptor 3 (Flt4)

Proceedings of the National Academy of Sciences - PNAS, 1998-01, Vol.95 (2), p.548-553

1998

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Current strategies for modulating lymphangiogenesis signalling pathways in human disease

Current medicinal chemistry, 2006-03, Vol.13 (7), p.783-792

2006

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Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D

The Journal of experimental medicine, 2003-09, Vol.198 (6), p.863-868

2003

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Molecular targeting of lymphatics for therapy

Current pharmaceutical design, 2004, Vol.10 (1), p.65-74

2004

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Adenoviral catheter-mediated intramyocardial gene transfer using the mature form of vascular endothelial growth factor-D induces transmural angiogenesis in porcine heart

Circulation (New York, N.Y.), 2004-03, Vol.109 (8), p.1029-1035

2004

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VEGF-D is an X-linked/AP-1 regulated putative onco-angiogen in human glioblastoma multiforme

Molecular medicine (Cambridge, Mass.), 2001-09, Vol.7 (9), p.598-608

2001

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The vascular endothelial growth factor family; proteins which guide the development of the vasculature

International journal of experimental pathology, 1998-10, Vol.79 (5), p.255-265

1998

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VEGF‐C and VEGF‐D expression in neuroendocrine cells and their receptor, VEGFR‐3, in fenestrated blood vessels in human tissues

The FASEB journal, 2000-10, Vol.14 (13), p.2087-2096

2000

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Biosynthesis of Vascular Endothelial Growth Factor-D Involves Proteolytic Processing Which Generates Non-covalent Homodimers

The Journal of biological chemistry, 1999-11, Vol.274 (45), p.32127-32136

1999

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Thyroxine transport from blood to brain via transthyretin synthesis in choroid plexus

American journal of physiology. Regulatory, integrative and comparative physiology, 1990-02, Vol.258 (2), p.338-R345

1990

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Vascular endothelial growth factor-D induces lymphangiogenesis and lymphatic metastasis in models of ductal pancreatic cancer

International journal of oncology, 2005-09, Vol.27 (3), p.669

2005

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The Specificity of Receptor Binding by Vascular Endothelial Growth Factor-D Is Different in Mouse and Man

The Journal of biological chemistry, 2001-06, Vol.276 (22), p.19166-19171

2001

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Growth factors regulating lymphatic vessels

Current topics in microbiology and immunology, 2000, Vol.251, p.75

2000

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A simple and rapid method for genetic transformation of lactic streptococci by electroporation

Applied and Environmental Microbiology, 1988-03, Vol.54 (3), p.655-660

1988

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Viral Vascular Endothelial Growth Factors Vary Extensively in Amino Acid Sequence, Receptor-binding Specificities, and the Ability to Induce Vascular Permeability yet Are Uniformly Active Mitogens

The Journal of biological chemistry, 2003-09, Vol.278 (39), p.38004-38014

2003

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Targeting lymphangiogenesis to prevent tumour metastasis

A phase Ib/II translational study of sunitinib with neoadjuvant radiotherapy in soft-tissue sarcoma

Elevated level of inhibin-α subunit is pro-tumourigenic and pro-metastatic and associated with extracapsular spread in advanced prostate cancer

Lymphangiogenesis and cancer metastasis

Intestinal-specific activatable Myb initiates colon tumorigenesis in mice

VEGF-D promotes the metastatic spread of tumor cells via the lymphatics

Gene transfer using the mature form of VEGF-D reduces neointimal thickening through nitric oxide-dependent mechanism

Isolated lymphatic endothelial cells transduce growth, survival and migratory signals via the VEGF-C/D receptor VEGFR-3

VEGF-D Is the Strongest Angiogenic and Lymphangiogenic Effector Among VEGFs Delivered Into Skeletal Muscle via Adenoviruses

Signalling via vascular endothelial growth factor receptor-3 is sufficient for lymphangiogenesis in transgenic mice

Vascular Endothelial Growth Factor D (VEGF-D) is a Ligand for the Tyrosine Kinases VEGF Receptor 2 (Flk1) and VEGF Receptor 3 (Flt4)

Current strategies for modulating lymphangiogenesis signalling pathways in human disease

Plasmin activates the lymphangiogenic growth factors VEGF-C and VEGF-D

Molecular targeting of lymphatics for therapy

Adenoviral catheter-mediated intramyocardial gene transfer using the mature form of vascular endothelial growth factor-D induces transmural angiogenesis in porcine heart

VEGF-D is an X-linked/AP-1 regulated putative onco-angiogen in human glioblastoma multiforme

The vascular endothelial growth factor family; proteins which guide the development of the vasculature

VEGF‐C and VEGF‐D expression in neuroendocrine cells and their receptor, VEGFR‐3, in fenestrated blood vessels in human tissues

Biosynthesis of Vascular Endothelial Growth Factor-D Involves Proteolytic Processing Which Generates Non-covalent Homodimers

Thyroxine transport from blood to brain via transthyretin synthesis in choroid plexus

Vascular endothelial growth factor-D induces lymphangiogenesis and lymphatic metastasis in models of ductal pancreatic cancer

The Specificity of Receptor Binding by Vascular Endothelial Growth Factor-D Is Different in Mouse and Man

Growth factors regulating lymphatic vessels

A simple and rapid method for genetic transformation of lactic streptococci by electroporation

Viral Vascular Endothelial Growth Factors Vary Extensively in Amino Acid Sequence, Receptor-binding Specificities, and the Ability to Induce Vascular Permeability yet Are Uniformly Active Mitogens

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