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Physiology and pathophysiology of canonical transient receptor potential channels

The FASEB journal, 2009-02, Vol.23 (2), p.297-328

2009

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Canonical transient receptor potential 3 channels regulate mitochondrial calcium uptake

Proceedings of the National Academy of Sciences - PNAS, 2013-07, Vol.110 (27), p.11011-11016

2013

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Functional interactions among Orai1, TRPCs, and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/Icrac channels

Proceedings of the National Academy of Sciences - PNAS, 2008-02, Vol.105 (8), p.2895-2900

2008

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Evidence of a Role for Fibroblast Transient Receptor Potential Canonical 3 Ca2+ Channel in Renal Fibrosis

Journal of the American Society of Nephrology, 2015-08, Vol.26 (8), p.1855-1876

2015

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Orai proteins interact with TRPC channels and confer responsiveness to store depletion

Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (11), p.4682-4687

2007

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role for Orai in TRPC-mediated Ca²⁺ entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca²⁺ entry

Proceedings of the National Academy of Sciences - PNAS, 2009-03, Vol.106 (9), p.3202-3206

2009

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G protein Gαo is essential for vomeronasal function and aggressive behavior in mice

Proceedings of the National Academy of Sciences - PNAS, 2011-08, Vol.108 (31), p.12898-12903

2011

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Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on the Kcc2 promoter

Proceedings of the National Academy of Sciences - PNAS, 2013-03, Vol.110 (11), p.4315-4320

2013

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TRPC1 Channels Are Critical for Hypertrophic Signaling in the Heart

Circulation research, 2009-11, Vol.105 (10), p.1023-1030

2009

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Deletion of TRPC3 in Mice Reduces Store-Operated Ca2+ Influx and the Severity of Acute Pancreatitis

Gastroenterology (New York, N.Y. 1943), 2009-10, Vol.137 (4), p.1509-1517

2009

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Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms

Molecular pharmacology, 2013-02, Vol.83 (2), p.429-438

2013

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Classical Transient Receptor Potential 1 and 6 Contribute to Hypoxic Pulmonary Hypertension Through Differential Regulation of Pulmonary Vascular Functions

Hypertension (Dallas, Tex. 1979), 2014-01, Vol.63 (1), p.173-180

2014

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Genetic and Pharmacologic Inhibition of the Ca2+ Influx Channel TRPC3 Protects Secretory Epithelia From Ca2+ -Dependent Toxicity

Gastroenterology (New York, N.Y. 1943), 2011-06, Vol.140 (7), p.2107-2115.e4

2011

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TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells

Open biology, 2012-05, Vol.2 (5), p.120068-120068

2012

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Critical role of canonical transient receptor potential channel 7 in initiation of seizures

Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (31), p.11533-11538

2014

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TRPC1 proteins confer PKC and phosphoinositol activation on native heteromeric TRPC1/C5 channels in vascular smooth muscle: comparative study of wild‐type and TRPC1−/− mice

The FASEB journal, 2012-01, Vol.26 (1), p.409-419

2012

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Transient receptor potential canonical type 3 channels facilitate endothelium-derived hyperpolarization-mediated resistance artery vasodilator activity

Cardiovascular research, 2012-09, Vol.95 (4), p.439-447

2012

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Development of the mammalian axial skeleton requires signaling through the Gαᵢ subfamily of heterotrimeric G proteins

Proceedings of the National Academy of Sciences - PNAS, 2012-12, Vol.109 (52), p.21366-21371

2012

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Resistance to pathologic cardiac hypertrophy and reduced expression of CaV1.2 in Trpc3-depleted mice

Molecular and cellular biochemistry, 2016-10, Vol.421 (1-2), p.55-65

2016

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Transient receptor potential canonical type 3 channels control the vascular contractility of mouse mesenteric arteries

PloS one, 2014-10, Vol.9 (10), p.e110413

2014

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Activation of Endothelial Transient Receptor Potential C3 Channel Is Required for Small Conductance Calcium‐Activated Potassium Channel Activation and Sustained Endothelial Hyperpolarization and Vasodilation of Cerebral Artery

Journal of the American Heart Association, 2014-08, Vol.3 (4), p.n/a

2014

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Impairment of survival signaling and efferocytosis in TRPC3-deficient macrophages

Biochemical and biophysical research communications, 2011-07, Vol.410 (3), p.643-647

2011

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Ouabain-induced Signaling and Vascular Smooth Muscle Cell Proliferation

The Journal of biological chemistry, 2001-12, Vol.276 (49), p.46605-46611

2001

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IEX-1 deficiency protects against colonic cancer

Molecular cancer research, 2012-06, Vol.10 (6), p.760-767

2012

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XLαs, the Extra-Long Form of the α-Subunit of the Gs G Protein, Is Significantly Longer Than Suspected, and So Is Its Companion Alex

Proceedings of the National Academy of Sciences - PNAS, 2004-06, Vol.101 (22), p.8366-8371

2004

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Physiology and pathophysiology of canonical transient receptor potential channels

Canonical transient receptor potential 3 channels regulate mitochondrial calcium uptake

Functional interactions among Orai1, TRPCs, and STIM1 suggest a STIM-regulated heteromeric Orai/TRPC model for SOCE/Icrac channels

Evidence of a Role for Fibroblast Transient Receptor Potential Canonical 3 Ca2+ Channel in Renal Fibrosis

Orai proteins interact with TRPC channels and confer responsiveness to store depletion

role for Orai in TRPC-mediated Ca²⁺ entry suggests that a TRPC:Orai complex may mediate store and receptor operated Ca²⁺ entry

G protein Gαo is essential for vomeronasal function and aggressive behavior in mice

Bisphenol A delays the perinatal chloride shift in cortical neurons by epigenetic effects on the Kcc2 promoter

TRPC1 Channels Are Critical for Hypertrophic Signaling in the Heart

Deletion of TRPC3 in Mice Reduces Store-Operated Ca2+ Influx and the Severity of Acute Pancreatitis

Canonical transient receptor channel 5 (TRPC5) and TRPC1/4 contribute to seizure and excitotoxicity by distinct cellular mechanisms

Classical Transient Receptor Potential 1 and 6 Contribute to Hypoxic Pulmonary Hypertension Through Differential Regulation of Pulmonary Vascular Functions

Genetic and Pharmacologic Inhibition of the Ca2+ Influx Channel TRPC3 Protects Secretory Epithelia From Ca2+ -Dependent Toxicity

TRPC3 and TRPC6 are essential for normal mechanotransduction in subsets of sensory neurons and cochlear hair cells

Critical role of canonical transient receptor potential channel 7 in initiation of seizures

TRPC1 proteins confer PKC and phosphoinositol activation on native heteromeric TRPC1/C5 channels in vascular smooth muscle: comparative study of wild‐type and TRPC1−/− mice

Transient receptor potential canonical type 3 channels facilitate endothelium-derived hyperpolarization-mediated resistance artery vasodilator activity

Development of the mammalian axial skeleton requires signaling through the Gαᵢ subfamily of heterotrimeric G proteins

Resistance to pathologic cardiac hypertrophy and reduced expression of CaV1.2 in Trpc3-depleted mice

Transient receptor potential canonical type 3 channels control the vascular contractility of mouse mesenteric arteries

Activation of Endothelial Transient Receptor Potential C3 Channel Is Required for Small Conductance Calcium‐Activated Potassium Channel Activation and Sustained Endothelial Hyperpolarization and Vasodilation of Cerebral Artery

Impairment of survival signaling and efferocytosis in TRPC3-deficient macrophages

Ouabain-induced Signaling and Vascular Smooth Muscle Cell Proliferation

IEX-1 deficiency protects against colonic cancer

XLαs, the Extra-Long Form of the α-Subunit of the Gs G Protein, Is Significantly Longer Than Suspected, and So Is Its Companion Alex

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