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1,2,4-Oxadiazole derivatives targeting EGFR and c-Met degradation in TKI resistant NSCLC

European journal of medicinal chemistry, 2019-11, Vol.182, p.111607-111607, Article 111607

2019

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3-[(6-Arylamino)pyridazinylamino]benzoic acids: design, synthesis and in vitro evaluation of anticancer activity

Archives of Pharmacal Research, 2013, 36(1), , pp.41-50

2013

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3D-QSAR pharmacophore modelling, virtual screening and docking studies for lead discovery of a novel scaffold for VEGFR 2 inhibitors: Design, synthesis and biological evaluation

Bioorganic chemistry, 2019-08, Vol.89, p.102988, Article 102988

2019

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4-Substitutedphthalazines and phthalazinones: synthesis, characterization and β-adrenergic blocking activity

Medicinal chemistry research, 2013-03, Vol.22 (3), p.1057-1064

2013

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ACE inhibitors hypothesis generation for selective design, synthesis and biological evaluation of 3-mercapto-2-methyl-propanoyl-pyrrolidine-3-imine derivatives as antihypertensive agents

Bioorganic & medicinal chemistry, 2009-05, Vol.17 (10), p.3739-3746

2009

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Advances in the discovery of activin receptor-like kinase 5 (ALK5) inhibitors

Bioorganic chemistry, 2024-06, Vol.147, p.107332-107332, Article 107332

2024

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Alkoxyphenylthiazoles with broad-spectrum activity against multidrug-resistant gram-positive bacterial pathogens

European journal of medicinal chemistry, 2018-05, Vol.152, p.318-328

2018

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AML and FLT3: An update on FDA-approved or under review kinase inhibitors targeting FLT3 kinase

Egyptian Journal of Chemistry, 2024-05

2024

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Analogs design, synthesis and biological evaluation of peptidomimetics with potential anti-HCV activity

Bioorganic & medicinal chemistry, 2013-05, Vol.21 (10), p.2742-2755

2013

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Antimicrobial and Cytotoxicity Evaluation of New 3-Allyl-2-iminothiazolidin-4-ones

Egyptian Journal of Chemistry, 2021-09

2021

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ANTIPYRETIC, ANTINOCICEPTIVE AND ANTI-INFLAMMATORY ACTIVITIES OF CERTAIN γ-OXOBUTANOIC ACID DERIVATIVES

Medicinal chemistry research, 2005-01, Vol.14 (1), p.26-39

2005

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Applying ligands profiling using multiple extended electron distribution based field templates and feature trees similarity searching in the discovery of new generation of urea-based antineoplastic kinase inhibitors

PloS one, 2012-11, Vol.7 (11), p.e49284

2012

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Assessment of new anti-HER2 ligands using combined docking, QM/MM scoring and MD simulation

Journal of molecular graphics & modelling, 2013-03, Vol.40, p.91-98

2013

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Bio-guided chemical characterization and nano-formulation studies of selected edible volatile oils with potential antibacterial and anti-SARS-CoV-2 activities

Arabian journal of chemistry, 2023-07, Vol.16 (7), p.104813, Article 104813

2023

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Bio-guided chemical characterization and nano-formulation studies of selected edible volatile oils with potentials antibacterial and anti-SARS-CoV-2 activities

Arabian journal of chemistry, 2023-07, Vol.16 (7), p.104813-104813

2023

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Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021

The Lancet (British edition), 2024-05, Vol.403 (10440), p.2204-2256

2024

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ChemInform Abstract: Covalent EGFR Inhibitors: Binding Mechanisms, Synthetic Approaches, and Clinical Profiles

ChemInform, 2016-09, Vol.47 (39), p.no-no

2016

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ChemInform Abstract: Design, Synthesis and in vitro anti-Proliferative Activity of 4,6-Quinazolinediamines as Potent EGFR-TK Inhibitors

ChemInform, 2013-07, Vol.44 (27), p.no-no

2013

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ChemInform Abstract: Quinoxaline‐Based Scaffolds Targeting Tyrosine Kinases and Their Potential Anticancer Activity

ChemInform, 2016-06, Vol.47 (25), p.no-no

2016

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Chimeric HDAC inhibitors: Comprehensive review on the HDAC‐based strategies developed to combat cancer

Medicinal research reviews, 2018-11, Vol.38 (6), p.2058-2109

2018

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Click and Release: SO 2 Prodrugs with Tunable Release Rates

Organic letters, 2017-02, Vol.19 (4), p.818-821

2017

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Click and Release: SO2 Prodrugs with Tunable Release Rates

Organic letters, 2017-02, Vol.19 (4), p.818-821

2017

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Covalent EGFR Inhibitors: Binding Mechanisms, Synthetic Approaches, and Clinical Profiles

Archiv der Pharmazie (Weinheim), 2016-08, Vol.349 (8), p.573-593

2016

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1,2,4-Oxadiazole derivatives targeting EGFR and c-Met degradation in TKI resistant NSCLC

3-[(6-Arylamino)pyridazinylamino]benzoic acids: design, synthesis and in vitro evaluation of anticancer activity

3D-QSAR pharmacophore modelling, virtual screening and docking studies for lead discovery of a novel scaffold for VEGFR 2 inhibitors: Design, synthesis and biological evaluation

4-Substitutedphthalazines and phthalazinones: synthesis, characterization and β-adrenergic blocking activity

ACE inhibitors hypothesis generation for selective design, synthesis and biological evaluation of 3-mercapto-2-methyl-propanoyl-pyrrolidine-3-imine derivatives as antihypertensive agents

Advances in the discovery of activin receptor-like kinase 5 (ALK5) inhibitors

Alkoxyphenylthiazoles with broad-spectrum activity against multidrug-resistant gram-positive bacterial pathogens

AML and FLT3: An update on FDA-approved or under review kinase inhibitors targeting FLT3 kinase

Analogs design, synthesis and biological evaluation of peptidomimetics with potential anti-HCV activity

Antimicrobial and Cytotoxicity Evaluation of New 3-Allyl-2-iminothiazolidin-4-ones

ANTIPYRETIC, ANTINOCICEPTIVE AND ANTI-INFLAMMATORY ACTIVITIES OF CERTAIN γ-OXOBUTANOIC ACID DERIVATIVES

Applying ligands profiling using multiple extended electron distribution based field templates and feature trees similarity searching in the discovery of new generation of urea-based antineoplastic kinase inhibitors

Assessment of new anti-HER2 ligands using combined docking, QM/MM scoring and MD simulation

Bio-guided chemical characterization and nano-formulation studies of selected edible volatile oils with potential antibacterial and anti-SARS-CoV-2 activities

Bio-guided chemical characterization and nano-formulation studies of selected edible volatile oils with potentials antibacterial and anti-SARS-CoV-2 activities

Burden of disease scenarios for 204 countries and territories, 2022–2050: a forecasting analysis for the Global Burden of Disease Study 2021

ChemInform Abstract: Covalent EGFR Inhibitors: Binding Mechanisms, Synthetic Approaches, and Clinical Profiles

ChemInform Abstract: Design, Synthesis and in vitro anti-Proliferative Activity of 4,6-Quinazolinediamines as Potent EGFR-TK Inhibitors

ChemInform Abstract: Quinoxaline‐Based Scaffolds Targeting Tyrosine Kinases and Their Potential Anticancer Activity

Chimeric HDAC inhibitors: Comprehensive review on the HDAC‐based strategies developed to combat cancer

Click and Release: SO 2 Prodrugs with Tunable Release Rates

Click and Release: SO2 Prodrugs with Tunable Release Rates

Clinical and endoscopic characteristics of patients undergoing gastrointestinal endoscopic procedures in Egypt: a nationwide multicenter study

Correction: Clinical and endoscopic characteristics of patients undergoing gastrointestinal endoscopic procedures in Egypt: a nationwide multicenter study

Covalent EGFR Inhibitors: Binding Mechanisms, Synthetic Approaches, and Clinical Profiles

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