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Structural Basis of Wnt Signaling Inhibition by Dickkopf Binding to LRP5/6

Developmental cell, 2011-11, Vol.21 (5), p.862-873

2011

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R-Spondin family members regulate the Wnt pathway by a common mechanism

Molecular biology of the cell, 2008-06, Vol.19 (6), p.2588-2596

2008

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Modulating WNT receptor turnover for tissue repair

Nature biotechnology, 2012-09, Vol.30 (9), p.835-836

2012

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Activating Hair Follicle Stem Cells via R-spondin2 to Stimulate Hair Growth

Journal of investigative dermatology, 2016-08, Vol.136 (8), p.1549-1558

2016

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R-Spondin1 protects mice from chemotherapy or radiation-induced oral mucositis through the canonical Wnt/β-catenin pathway

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (7), p.2331-2336

2009

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R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6

Proceedings of the National Academy of Sciences - PNAS, 2007-09, Vol.104 (37), p.14700-14705

2007

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Targeting C-type lectin-like molecule-1 for antibody-mediated immunotherapy in acute myeloid leukemia

Haematologica (Roma), 2010-01, Vol.95 (1), p.71-78

2010

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R-Spondin Proteins: A Novel Link to β-catenin Activation

Cell cycle (Georgetown, Tex.), 2006-01, Vol.5 (1), p.23-26

2006

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rNAPc2 Inhibits Colorectal Cancer in Mice through Tissue Factor

Clinical cancer research, 2009-01, Vol.15 (1), p.208-216

2009

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Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

Cell, 1995-06, Vol.81 (7), p.1147-1157

1995

Volltextzugriff (PDF)

Proceedings: Debilitating Eye Diseases

Stem cells translational medicine, 2014-12, Vol.3 (12), p.1393-1397

2014

Volltextzugriff (PDF)

Tipping the balance: modulating the Wnt pathway for tissue repair

Trends in biotechnology (Regular ed.), 2009-03, Vol.27 (3), p.131-136

2009

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The Wiskott–Aldrich syndrome protein directs actin-based motility by stimulating actin nucleation with the Arp2/3 complex

Current biology, 1999-05, Vol.9 (10), p.555,S1-558,S1

1999

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The biochemical basis of the NADPH oxidase of phagocytes

Trends in Biochemical Sciences, 1993-02, Vol.18 (2), p.43-47

1993

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Critical and Distinct Roles of Amino- and Carboxyl-terminal Sequences in Regulation of the Biological Activity of the Chp Atypical Rho GTPase

The Journal of biological chemistry, 2005-04, Vol.280 (14), p.13784-13792

2005

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A Role for Wiskott-Aldrich Syndrome Protein in T-cell Receptor-mediated Transcriptional Activation Independent of Actin Polymerization

The Journal of biological chemistry, 2001-06, Vol.276 (24), p.21450-21457

2001

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Single Lgr5 stem cells build cryptvillus structures in vitro without a mesenchymal niche

Nature, 2009-05, Vol.459 (7244), p.262-265

2009

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Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

Nature (London), 1991-10, Vol.353 (6345), p.668-670

1991

Volltextzugriff (PDF)

Proceedings: Using Stem Cell Therapies to Reestablish Osteogenic Capability for Bone Regeneration

Stem cells translational medicine, 2015-11, Vol.4 (11), p.1247-1250

2015

Volltextzugriff (PDF)

Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

Cell stem cell, 2010-01, Vol.6 (1), p.25-36

2010

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Modulating WNT receptor turnover for tissue repair: new mechanistic insight into the regulation of WNT signaling supports efforts to target this pathway in adult stem cells for regenerative medicine

Nature biotechnology, 2012-09, Vol.30 (9), p.835

2012

Volltextzugriff (PDF)

The Cdc42/Rac Interactive Binding Region Motif of the Wiskott Aldrich Syndrome Protein (WASP) Is Necessary but Not Sufficient for Tight Binding to Cdc42 and Structure Formation

The Journal of biological chemistry, 1998-07, Vol.273 (29), p.18067-18076

1998

Volltextzugriff (PDF)

p21-Activated Kinase 1 Plays a Critical Role in Cellular Activation by Nef

Molecular and Cellular Biology, 2000-04, Vol.20 (7), p.2619-2627

2000

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Role for the Rho-family GTPase Cdc42 in yeast mating-pheromone signal pathway

Nature (London), 1995-08, Vol.376 (6542), p.702-705

1995

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The Ras/Rac1/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes

Molecular biology of the cell, 1998-03, Vol.9 (3), p.561-573

1998

Volltextzugriff (PDF)

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Structural Basis of Wnt Signaling Inhibition by Dickkopf Binding to LRP5/6

R-Spondin family members regulate the Wnt pathway by a common mechanism

Modulating WNT receptor turnover for tissue repair

Activating Hair Follicle Stem Cells via R-spondin2 to Stimulate Hair Growth

R-Spondin1 protects mice from chemotherapy or radiation-induced oral mucositis through the canonical Wnt/β-catenin pathway

R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6

Targeting C-type lectin-like molecule-1 for antibody-mediated immunotherapy in acute myeloid leukemia

R-Spondin Proteins: A Novel Link to β-catenin Activation

rNAPc2 Inhibits Colorectal Cancer in Mice through Tissue Factor

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

Proceedings: Debilitating Eye Diseases

Tipping the balance: modulating the Wnt pathway for tissue repair

The Wiskott–Aldrich syndrome protein directs actin-based motility by stimulating actin nucleation with the Arp2/3 complex

The biochemical basis of the NADPH oxidase of phagocytes

Critical and Distinct Roles of Amino- and Carboxyl-terminal Sequences in Regulation of the Biological Activity of the Chp Atypical Rho GTPase

A Role for Wiskott-Aldrich Syndrome Protein in T-cell Receptor-mediated Transcriptional Activation Independent of Actin Polymerization

Single Lgr5 stem cells build cryptvillus structures in vitro without a mesenchymal niche

Activation of the NADPH oxidase involves the small GTP-binding protein p21rac1

Proceedings: Using Stem Cell Therapies to Reestablish Osteogenic Capability for Bone Regeneration

Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro

Modulating WNT receptor turnover for tissue repair: new mechanistic insight into the regulation of WNT signaling supports efforts to target this pathway in adult stem cells for regenerative medicine

The Cdc42/Rac Interactive Binding Region Motif of the Wiskott Aldrich Syndrome Protein (WASP) Is Necessary but Not Sufficient for Tight Binding to Cdc42 and Structure Formation

p21-Activated Kinase 1 Plays a Critical Role in Cellular Activation by Nef

Role for the Rho-family GTPase Cdc42 in yeast mating-pheromone signal pathway

The Ras/Rac1/Cdc42/SEK/JNK/c-Jun cascade is a key pathway by which agonists stimulate DNA synthesis in primary cultures of rat hepatocytes

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