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Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new application

Biomedicine & pharmacotherapy, 2022-01, Vol.145, p.112455, Article 112455

2022

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Canagliflozin-loaded chitosan-hyaluronic acid microspheres modulate AMPK/NF-κB/NLRP3 axis: A new paradigm in the rectal therapy of ulcerative colitis

Biomedicine & pharmacotherapy, 2022-09, Vol.153, p.113409-113409, Article 113409

2022

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Innovative challenge for the inhibition of hepatocellular carcinoma progression by combined targeting of HSP90 and STAT3/HIF-1α signaling

Biomedicine & pharmacotherapy, 2023-02, Vol.158, p.114196-114196, Article 114196

2023

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Combining the HSP90 inhibitor TAS-116 with metformin effectively degrades the NLRP3 and attenuates inflammasome activation in rats: A new management paradigm for ulcerative colitis

Biomedicine & pharmacotherapy, 2022-09, Vol.153, p.113247-113247, Article 113247

2022

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Vildagliptin/pioglitazone combination improved the overall glycemic control in type I diabetic rats

Canadian journal of physiology and pharmacology, 2018-08, Vol.96 (8), p.710-718

2018

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AKT-AMPKα-mTOR-dependent HIF-1α Activation is a New Therapeutic Target for Cancer Treatment: A Novel Approach to Repositioning the Antidiabetic Drug Sitagliptin for the Management of Hepatocellular Carcinoma

Frontiers in pharmacology, 2022-01, Vol.12, p.720173-720173

2022

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STA-9090 in combination with a statin exerts enhanced protective effects in rats fed a high-fat diet and exposed to diethylnitrosamine and thioacetamide

Frontiers in pharmacology, 2024-09, Vol.15, p.1454829

2024

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Carbocisteine as a Modulator of Nrf2/HO-1 and NFκB Interplay in Rats: New Inspiration for the Revival of an Old Drug for Treating Ulcerative Colitis

Frontiers in pharmacology, 2022-06, Vol.13, p.887233-887233

2022

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Evaluation of the Corneal Endothelium Following Cataract Surgery in Diabetic and Non-Diabetic Patients

Diagnostics (Basel), 2023-03, Vol.13 (6), p.1115

2023

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Coxarthrosis etiology influences the patients’ quality of life in the preoperative and postoperative phase of total hip arthroplasty

Journal of Mind and Medical Sciences, 2023-10, Vol.10 (2), p.COV13-294

2023

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Benzo[a]pyrene immunogenetics and immune archetype reprogramming of lung

Toxicology (Amsterdam), 2021-11, Vol.463, p.152994-152994, Article 152994

2021

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Telmisartan alleviates alcohol-induced liver injury by activation of PPAR-γ/ Nrf-2 crosstalk in mice

International immunopharmacology, 2021-10, Vol.99, p.107963, Article 107963

2021

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Navigating liver targeting: Fine-tuning chitosan nanocarriers through saccharide modification

Journal of drug delivery science and technology, 2024-05, Vol.95, p.105644, Article 105644

2024

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Alpha-Asarone attenuates alcohol-induced hepatotoxicity in a murine model by ameliorating oxidative stress, inflammation, and modulating apoptotic-Autophagic cell death

Toxicology and applied pharmacology, 2024-09, Vol.490, p.117041, Article 117041

2024

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Cell cycle machinery in oncology: A comprehensive review of therapeutic targets

The FASEB journal, 2024-06, Vol.38 (11), p.e23734-n/a

2024

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Empagliflozin ameliorates ethanol-induced liver injury by modulating NF-κB/Nrf-2/PPAR-γ interplay in mice

Life sciences (1973), 2020-09, Vol.256, p.117908, Article 117908

2020

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The multifaceted role of beta‐blockers in overcoming cancer progression and drug resistance: Extending beyond cardiovascular disorders

The FASEB journal, 2024-07, Vol.38 (13), p.e23813-n/a

2024

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Blunting p38 MAPKα and ERK1/2 activities by empagliflozin enhances the antifibrotic effect of metformin and augments its AMPK-induced NF-κB inactivation in mice intoxicated with carbon tetrachloride

Life sciences (1973), 2021-12, Vol.286, p.120070-120070, Article 120070

2021

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Interference With the AMPKα/mTOR/NLRP3 Signaling and the IL-23/IL-17 Axis Effectively Protects Against the Dextran Sulfate Sodium Intoxication in Rats: A New Paradigm in Empagliflozin and Metformin Reprofiling for the Management of Ulcerative Colitis

Frontiers in pharmacology, 2021-08, Vol.12, p.719984-719984

2021

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Global multi-stakeholder endorsement of the MAFLD definition

The lancet. Gastroenterology & hepatology, 2022-05, Vol.7 (5), p.388-390

2022

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Chronomodulated Administration of Chemotherapy in Advanced Colorectal Cancer: A Systematic Review and Meta-Analysis

Curēus (Palo Alto, CA), 2023-03

2023

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Study of Inflammatory Markers in Patients with Uncontrolled Generalized Motor Tonic–Clonic Seizures

QJM : An International Journal of Medicine, 2024-07, Vol.117 (Supplement_1)

2024

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Laser hemorrhoidoplasty combined with blind hemorrhoidal artery ligation compared to Milligan–Morgan hemorrhoidectomy in patients with second and third degree piles; a prospective randomized study

The Egyptian journal of surgery : official organ of the Egyptian Society of Surgeons = Majallat al-jirāhah al-Misrīyah, 2023-07, Vol.42 (3), p.669-675

2023

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The Effect of Virtual Reality-Based Therapy on Improving Upper Limb Functions in Individuals With Stroke: A Randomized Control Trial

Frontiers in aging neuroscience, 2021-11, Vol.13, p.731343-731343

2021

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Empagliflozin adjunct with metformin for the inhibition of hepatocellular carcinoma progression: Emerging approach for new application

Canagliflozin-loaded chitosan-hyaluronic acid microspheres modulate AMPK/NF-κB/NLRP3 axis: A new paradigm in the rectal therapy of ulcerative colitis

Innovative challenge for the inhibition of hepatocellular carcinoma progression by combined targeting of HSP90 and STAT3/HIF-1α signaling

Combining the HSP90 inhibitor TAS-116 with metformin effectively degrades the NLRP3 and attenuates inflammasome activation in rats: A new management paradigm for ulcerative colitis

Vildagliptin/pioglitazone combination improved the overall glycemic control in type I diabetic rats

AKT-AMPKα-mTOR-dependent HIF-1α Activation is a New Therapeutic Target for Cancer Treatment: A Novel Approach to Repositioning the Antidiabetic Drug Sitagliptin for the Management of Hepatocellular Carcinoma

STA-9090 in combination with a statin exerts enhanced protective effects in rats fed a high-fat diet and exposed to diethylnitrosamine and thioacetamide

Carbocisteine as a Modulator of Nrf2/HO-1 and NFκB Interplay in Rats: New Inspiration for the Revival of an Old Drug for Treating Ulcerative Colitis

Evaluation of the Corneal Endothelium Following Cataract Surgery in Diabetic and Non-Diabetic Patients

Coxarthrosis etiology influences the patients’ quality of life in the preoperative and postoperative phase of total hip arthroplasty

Benzo[a]pyrene immunogenetics and immune archetype reprogramming of lung

Telmisartan alleviates alcohol-induced liver injury by activation of PPAR-γ/ Nrf-2 crosstalk in mice

Navigating liver targeting: Fine-tuning chitosan nanocarriers through saccharide modification

Alpha-Asarone attenuates alcohol-induced hepatotoxicity in a murine model by ameliorating oxidative stress, inflammation, and modulating apoptotic-Autophagic cell death

Cell cycle machinery in oncology: A comprehensive review of therapeutic targets

Empagliflozin ameliorates ethanol-induced liver injury by modulating NF-κB/Nrf-2/PPAR-γ interplay in mice

The multifaceted role of beta‐blockers in overcoming cancer progression and drug resistance: Extending beyond cardiovascular disorders

Ambroxol, a mucolytic agent, boosts HO‐1, suppresses NF‐κB, and decreases the susceptibility of the inflamed rat colon to apoptosis: A new treatment option for treating ulcerative colitis

Blunting p38 MAPKα and ERK1/2 activities by empagliflozin enhances the antifibrotic effect of metformin and augments its AMPK-induced NF-κB inactivation in mice intoxicated with carbon tetrachloride

Interference With the AMPKα/mTOR/NLRP3 Signaling and the IL-23/IL-17 Axis Effectively Protects Against the Dextran Sulfate Sodium Intoxication in Rats: A New Paradigm in Empagliflozin and Metformin Reprofiling for the Management of Ulcerative Colitis

Global multi-stakeholder endorsement of the MAFLD definition

Chronomodulated Administration of Chemotherapy in Advanced Colorectal Cancer: A Systematic Review and Meta-Analysis

Study of Inflammatory Markers in Patients with Uncontrolled Generalized Motor Tonic–Clonic Seizures

Laser hemorrhoidoplasty combined with blind hemorrhoidal artery ligation compared to Milligan–Morgan hemorrhoidectomy in patients with second and third degree piles; a prospective randomized study

The Effect of Virtual Reality-Based Therapy on Improving Upper Limb Functions in Individuals With Stroke: A Randomized Control Trial

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