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Investigation of the carbonic anhydrase inhibitory activity of benzenesulfonamides incorporating substituted fused‐pyrimidine tails

Archiv der Pharmazie (Weinheim), 2022-11, Vol.355 (11), p.e2200274-n/a

2022

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Novel 2‐substituted thioquinazoline‐benzenesulfonamide derivatives as carbonic anhydrase inhibitors with potential anticancer activity

Archiv der Pharmazie (Weinheim), 2022-12, Vol.355 (12), p.e2200180-n/a

2022

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Diphenyl urea‐benzylidene acetohydrazide hybrids as fibroblast growth factor receptor 1 inhibitors and anticancer agents

Drug development research, 2024-09, Vol.85 (6), p.e22249-n/a

2024

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Novel benzenesulfonamide‐thiouracil conjugates with a flexible N‐ethyl acetamide linker as selective CA IX and CA XII inhibitors

Archiv der Pharmazie (Weinheim), 2023-02, Vol.356 (2), p.e2200434-n/a

2023

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Benzimidazole‐oxindole hybrids: A novel class of selective dual CDK2 and GSK‐3β inhibitors of potent anticancer activity

Archiv der Pharmazie (Weinheim), 2024-10, Vol.357 (10), p.e2300721-n/a

2024

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Quinazoline‐oxindole hybrids as angiokinase inhibitors and anticancer agents: Design, synthesis, biological evaluation, and molecular docking studies

Archiv der Pharmazie (Weinheim), 2024-10, Vol.357 (10), p.e2300682-n/a

2024

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Design, synthesis, and molecular docking of novel 2‐arylbenzothiazole multiangiokinase inhibitors targeting breast cancer

Archiv der Pharmazie (Weinheim), 2020-04, Vol.353 (4), p.e1900340-n/a

2020

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Synthesis, crystal structure, and ADME prediction studies of novel imidazopyrimidines as antibacterial and cytotoxic agents

Archiv der Pharmazie (Weinheim), 2020-03, Vol.353 (3), p.e1900271-n/a

2020

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New 2,4‐disubstituted‐2‐thiopyrimidines as VEGFR‐2 inhibitors: Design, synthesis, and biological evaluation

Archiv der Pharmazie (Weinheim), 2019-11, Vol.352 (11), p.e1900089-n/a

2019

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Oxindole–benzothiazole hybrids as CDK2 inhibitors and anticancer agents: design, synthesis and biological evaluation

BMC chemistry, 2024-09, Vol.18 (1), p.169-19, Article 169

Abdel-Mohsen, Heba T.

2024

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Recent Advances in Structural Optimization of Quinazoline-Based Protein Kinase Inhibitors for Cancer Therapy (2021-Present)

Molecules (Basel, Switzerland), 2024-02, Vol.29 (4), p.875

2024

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Targeting Receptor Tyrosine Kinase VEGFR-2 in Hepatocellular Cancer: Rational Design, Synthesis and Biological Evaluation of 1,2-Disubstituted Benzimidazoles

Molecules (Basel, Switzerland), 2020-02, Vol.25 (4), p.770

2020

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Laccase-catalyzed oxidation of Hantzsch 1,4-dihydropyridines to pyridines and a new one pot synthesis of pyridines

Green chemistry : an international journal and green chemistry resource : GC, 2012-01, Vol.14 (10), p.2686-2690

2012

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Receptor-based pharmacophore modeling, molecular docking, synthesis and biological evaluation of novel VEGFR-2, FGFR-1, and BRAF multi-kinase inhibitors

BMC chemistry, 2024-02, Vol.18 (1), p.42-42, Article 42

2024

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Benzimidazole-dioxoisoindoline conjugates as dual VEGFR-2 and FGFR-1 inhibitors: design, synthesis, biological investigation, molecular docking studies and ADME predictions

RSC advances, 2024-09, Vol.14 (39), p.28889-28903

2024

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Laccase-catalyzed synthesis of catechol thioethers by reaction of catechols with thiols using air as an oxidant

Green chemistry : an international journal and green chemistry resource : GC, 2014-01, Vol.16 (1), p.90-95

2014

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Application of the dual-tail approach for the design and synthesis of novel Thiopyrimidine–Benzenesulfonamide hybrids as selective carbonic anhydrase inhibitors

European journal of medicinal chemistry, 2022-01, Vol.228, p.114004, Article 114004

2022

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Design, synthesis, molecular docking and cytotoxic evaluation of novel 2-furybenzimidazoles as VEGFR-2 inhibitors

European journal of medicinal chemistry, 2017-08, Vol.136, p.315-329

2017

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Synthesis of disulfides by laccase-catalyzed oxidative coupling of heterocyclic thiols

Green chemistry : an international journal and green chemistry resource : GC, 2013-01, Vol.15 (6), p.1490-1495

2013

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Novel potent substituted 4-amino-2-thiopyrimidines as dual VEGFR-2 and BRAF kinase inhibitors

European journal of medicinal chemistry, 2019-10, Vol.179, p.707-722

2019

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Rational design and synthesis of novel quinazolinone N-acetohydrazides as type II multi-kinase inhibitors and potential anticancer agents

Bioorganic chemistry, 2024-01, Vol.142, p.106920-106920, Article 106920

2024

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Laccase-Catalyzed Domino Reaction between Catechols and 6‑Substituted 1,2,3,4-Tetrahydro-4-oxo-2-thioxo-5-pyrimidinecarbonitriles for the Synthesis of Pyrimidobenzothiazole Derivatives

Journal of organic chemistry, 2013-08, Vol.78 (16), p.7986-8003

2013

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Benzimidazole-oxindole hybrids as multi-kinase inhibitors targeting melanoma

Bioorganic chemistry, 2024-05, Vol.146, p.107243-107243, Article 107243

2024

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Design, synthesis and anticancer activity of novel 2-arylbenzimidazole/2-thiopyrimidines and 2-thioquinazolin-4(3H)-ones conjugates as targeted RAF and VEGFR-2 kinases inhibitors

Bioorganic chemistry, 2022-09, Vol.126, p.105883-105883, Article 105883

2022

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New thiopyrimidine-benzenesulfonamide conjugates as selective carbonic anhydrase II inhibitors: synthesis, in vitro biological evaluation, and molecular docking studies

Bioorganic & medicinal chemistry, 2020-03, Vol.28 (5), p.115329, Article 115329

2020

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Investigation of the carbonic anhydrase inhibitory activity of benzenesulfonamides incorporating substituted fused‐pyrimidine tails

Novel 2‐substituted thioquinazoline‐benzenesulfonamide derivatives as carbonic anhydrase inhibitors with potential anticancer activity

Diphenyl urea‐benzylidene acetohydrazide hybrids as fibroblast growth factor receptor 1 inhibitors and anticancer agents

Novel benzenesulfonamide‐thiouracil conjugates with a flexible N‐ethyl acetamide linker as selective CA IX and CA XII inhibitors

Benzimidazole‐oxindole hybrids: A novel class of selective dual CDK2 and GSK‐3β inhibitors of potent anticancer activity

Quinazoline‐oxindole hybrids as angiokinase inhibitors and anticancer agents: Design, synthesis, biological evaluation, and molecular docking studies

Design, synthesis, and molecular docking of novel 2‐arylbenzothiazole multiangiokinase inhibitors targeting breast cancer

Synthesis, crystal structure, and ADME prediction studies of novel imidazopyrimidines as antibacterial and cytotoxic agents

New 2,4‐disubstituted‐2‐thiopyrimidines as VEGFR‐2 inhibitors: Design, synthesis, and biological evaluation

Oxindole–benzothiazole hybrids as CDK2 inhibitors and anticancer agents: design, synthesis and biological evaluation

Recent Advances in Structural Optimization of Quinazoline-Based Protein Kinase Inhibitors for Cancer Therapy (2021-Present)

Targeting Receptor Tyrosine Kinase VEGFR-2 in Hepatocellular Cancer: Rational Design, Synthesis and Biological Evaluation of 1,2-Disubstituted Benzimidazoles

Laccase-catalyzed oxidation of Hantzsch 1,4-dihydropyridines to pyridines and a new one pot synthesis of pyridines

Receptor-based pharmacophore modeling, molecular docking, synthesis and biological evaluation of novel VEGFR-2, FGFR-1, and BRAF multi-kinase inhibitors

Benzimidazole-dioxoisoindoline conjugates as dual VEGFR-2 and FGFR-1 inhibitors: design, synthesis, biological investigation, molecular docking studies and ADME predictions

Laccase-catalyzed synthesis of catechol thioethers by reaction of catechols with thiols using air as an oxidant

Application of the dual-tail approach for the design and synthesis of novel Thiopyrimidine–Benzenesulfonamide hybrids as selective carbonic anhydrase inhibitors

Design, synthesis, molecular docking and cytotoxic evaluation of novel 2-furybenzimidazoles as VEGFR-2 inhibitors

Synthesis of disulfides by laccase-catalyzed oxidative coupling of heterocyclic thiols

Novel potent substituted 4-amino-2-thiopyrimidines as dual VEGFR-2 and BRAF kinase inhibitors

Rational design and synthesis of novel quinazolinone N-acetohydrazides as type II multi-kinase inhibitors and potential anticancer agents

Laccase-Catalyzed Domino Reaction between Catechols and 6‑Substituted 1,2,3,4-Tetrahydro-4-oxo-2-thioxo-5-pyrimidinecarbonitriles for the Synthesis of Pyrimidobenzothiazole Derivatives

Benzimidazole-oxindole hybrids as multi-kinase inhibitors targeting melanoma

Design, synthesis and anticancer activity of novel 2-arylbenzimidazole/2-thiopyrimidines and 2-thioquinazolin-4(3H)-ones conjugates as targeted RAF and VEGFR-2 kinases inhibitors

New thiopyrimidine-benzenesulfonamide conjugates as selective carbonic anhydrase II inhibitors: synthesis, in vitro biological evaluation, and molecular docking studies

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