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Transmission of multiple system atrophy prions to transgenic mice

Proceedings of the National Academy of Sciences - PNAS, 2013-11, Vol.110 (48), p.19555-19560

2013

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Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

Proceedings of the National Academy of Sciences - PNAS, 2015-09, Vol.112 (38), p.E5308-E5317

2015

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Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (28), p.10323-10328

2014

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Purified and synthetic Alzheimer’s amyloid beta (Aβ) prions

Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (27), p.11025-11030

2012

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Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice

Proceedings of the National Academy of Sciences - PNAS, 2014-07, Vol.111 (28), p.10329-10334

2014

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Propagation of prions causing synucleinopathies in cultured cells

Proceedings of the National Academy of Sciences - PNAS, 2015-09, Vol.112 (35), p.E4949-E4958

2015

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Drug resistance confounding prion therapeutics

Proceedings of the National Academy of Sciences - PNAS, 2013-10, Vol.110 (44), p.E4160-E4169

2013

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Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCAA53T) mouse lines

Acta neuropathologica, 2019-03, Vol.137 (3), p.437-454

2019

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Phosphorylation of tau at a single residue inhibits binding to the E3 ubiquitin ligase, CHIP

Nature communications, 2024-09, Vol.15 (1), p.7972-15, Article 7972

2024

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Familial Parkinson’s point mutation abolishes multiple system atrophy prion replication

Proceedings of the National Academy of Sciences - PNAS, 2018-01, Vol.115 (2), p.409-414

2018

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Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy

PLoS pathogens, 2020-02, Vol.16 (2), p.e1008222-e1008222

2020

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Evidence that bank vole PrP is a universal acceptor for prions

PLoS pathogens, 2014-04, Vol.10 (4), p.e1003990-e1003990

2014

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The E46K mutation modulates α-synuclein prion replication in transgenic mice

PLoS pathogens, 2022-12, Vol.18 (12)

2022

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Prion Disease Induces Alzheimer Disease—Like Neuropathologic Changes

Journal of neuropathology and experimental neurology, 2015-09, Vol.74 (9), p.873-888

2015

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The E46K mutation modulates α-synuclein prion replication in transgenic mice

PLoS pathogens, 2022-12, Vol.18 (12), p.e1010956-e1010956

2022

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Towards authentic transgenic mouse models of heritable PrP prion diseases

Acta neuropathologica, 2016-10, Vol.132 (4), p.593-610

2016

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Use of a 2-aminothiazole to Treat Chronic Wasting Disease in Transgenic Mice

The Journal of infectious diseases, 2015-07, Vol.212 (suppl 1), p.S17-S25

2015

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Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains

The Journal of pharmacology and experimental therapeutics, 2015-10, Vol.355 (1), p.2-12

2015

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Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (9), p.3498-3503

2012

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Spontaneous generation of anchorless prions in transgenic mice

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (52), p.21223-21228

2011

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Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation

Annals of neurology, 2015-10, Vol.78 (4), p.540-553

2015

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Convection-enhanced delivery of AAV2-PrPshRNA in prion-infected mice

PloS one, 2014-05, Vol.9 (5), p.e98496-e98496

2014

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Oligodendroglial deletion of ESCRT-I component TSG101 causes spongiform encephalopathy

Biology of the cell, 2016-11, Vol.108 (11), p.324-337

2016

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Protease-resistant prions selectively decrease Shadoo protein

PLoS pathogens, 2011-11, Vol.7 (11), p.e1002382-e1002382

2011

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Levels of the Mahogunin Ring Finger 1 E3 ubiquitin ligase do not influence prion disease

PloS one, 2013-01, Vol.8 (1), p.e55575-e55575

2013

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Transmission of multiple system atrophy prions to transgenic mice

Evidence for α-synuclein prions causing multiple system atrophy in humans with parkinsonism

Serial propagation of distinct strains of Aβ prions from Alzheimer’s disease patients

Purified and synthetic Alzheimer’s amyloid beta (Aβ) prions

Distinct synthetic Aβ prion strains producing different amyloid deposits in bigenic mice

Propagation of prions causing synucleinopathies in cultured cells

Drug resistance confounding prion therapeutics

Multiple system atrophy prions retain strain specificity after serial propagation in two different Tg(SNCAA53T) mouse lines

Phosphorylation of tau at a single residue inhibits binding to the E3 ubiquitin ligase, CHIP

Familial Parkinson’s point mutation abolishes multiple system atrophy prion replication

Kinetics of α-synuclein prions preceding neuropathological inclusions in multiple system atrophy

Evidence that bank vole PrP is a universal acceptor for prions

The E46K mutation modulates α-synuclein prion replication in transgenic mice

Prion Disease Induces Alzheimer Disease—Like Neuropathologic Changes

The E46K mutation modulates α-synuclein prion replication in transgenic mice

Towards authentic transgenic mouse models of heritable PrP prion diseases

Use of a 2-aminothiazole to Treat Chronic Wasting Disease in Transgenic Mice

Different 2-Aminothiazole Therapeutics Produce Distinct Patterns of Scrapie Prion Neuropathology in Mouse Brains

Spontaneous generation of rapidly transmissible prions in transgenic mice expressing wild-type bank vole prion protein

Spontaneous generation of anchorless prions in transgenic mice

Modulation of Creutzfeldt-Jakob disease prion propagation by the A224V mutation

Convection-enhanced delivery of AAV2-PrPshRNA in prion-infected mice

Oligodendroglial deletion of ESCRT-I component TSG101 causes spongiform encephalopathy

Protease-resistant prions selectively decrease Shadoo protein

Levels of the Mahogunin Ring Finger 1 E3 ubiquitin ligase do not influence prion disease

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