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Animal Models to Understand the Etiology and Pathophysiology of Polycystic Ovary Syndrome

Endocrine reviews, 2020-08, Vol.41 (4), p.538

2020

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Androgens in maternal vascular and placental function: implications for preeclampsia pathogenesis

Reproduction (Cambridge, England), 2018-11, Vol.156 (5), p.R155-R167

2018

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Epigenetic mechanism underlying the development of polycystic ovary syndrome (PCOS)-like phenotypes in prenatally androgenized rhesus monkeys

PloS one, 2011-11, Vol.6 (11), p.e27286-e27286

2011

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Ontogeny of polycystic ovary syndrome and insulin resistance in utero and early childhood

Fertility and sterility, 2013-07, Vol.100 (1), p.2-11

2013

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Mechanisms of intergenerational transmission of polycystic ovary syndrome

Reproduction (Cambridge, England), 2020-01, Vol.159 (1), p.R1-R13

2020

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Hyperandrogenic origins of polycystic ovary syndrome - implications for pathophysiology and therapy

Expert review of endocrinology & metabolism, 2019-03, Vol.14 (2), p.131-143

2019

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Hyperandrogenism Accompanies Increased Intra-Abdominal Fat Storage in Normal Weight Polycystic Ovary Syndrome Women

The journal of clinical endocrinology and metabolism, 2016-11, Vol.101 (11), p.4178-4188

2016

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Polycystic ovary syndrome as a plausible evolutionary outcome of metabolic adaptation

Reproductive biology and endocrinology, 2022-01, Vol.20 (1), p.12-12, Article 12

2022

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Early-to-mid gestation fetal testosterone increases right hand 2D:4D finger length ratio in polycystic ovary syndrome-like monkeys

PloS one, 2012-08, Vol.7 (8), p.e42372

2012

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Dexrazoxane Diminishes Doxorubicin-Induced Acute Ovarian Damage and Preserves Ovarian Function and Fecundity in Mice

PloS one, 2015-11, Vol.10 (11), p.e0142588

2015

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Translational Insight Into Polycystic Ovary Syndrome (PCOS) From Female Monkeys with PCOS-like Traits

Current pharmaceutical design, 2016-01, Vol.22 (36), p.5625-5633

2016

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Androgen Receptors in Multiple Organ Systems Provide Molecular Gateways to Polycystic Ovary Syndrome

Endocrinology (Philadelphia), 2020-08, Vol.161 (8), p.1

2020

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The marmoset monkey: a multi-purpose preclinical and translational model of human biology and disease

Drug discovery today, 2012-11, Vol.17 (21-22), p.1160-1165

2012

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Abnormal infant islet morphology precedes insulin resistance in PCOS-like monkeys

PloS one, 2014-09, Vol.9 (9), p.e106527-e106527

2014

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Fetal, infant, adolescent and adult phenotypes of polycystic ovary syndrome in prenatally androgenized female rhesus monkeys

American journal of primatology, 2009-09, Vol.71 (9), p.776-784

2009

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Environmental factors and puberty timing: expert panel research needs

Pediatrics (Evanston), 2008-02, Vol.121 Suppl 3 (Supplement_3), p.S192-S207

2008

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Acute doxorubicin insult in the mouse ovary is cell- and follicle-type dependent

PloS one, 2012-08, Vol.7 (8), p.e42293

2012

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Bortezomib prevents acute doxorubicin ovarian insult and follicle demise, improving the fertility window and pup birth weight in mice

PloS one, 2014-09, Vol.9 (9), p.e108174

2014

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Experimentally Induced Hyperinsulinemia Fails to Induce Polycystic Ovary Syndrome-like Traits in Female Rhesus Macaques

International journal of molecular sciences, 2022-02, Vol.23 (5), p.2635

2022

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Accelerated Episodic Luteinizing Hormone Release Accompanies Blunted Progesterone Regulation in PCOS-like Female Rhesus Monkeys (Macaca Mulatta) Exposed to Testosterone during Early-to-Mid Gestation

Neuroendocrinology, 2018-01, Vol.107 (2), p.133-146

2018

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Reproductive skew in female common marmosets: what can proximate mechanisms tell us about ultimate causes?

Proceedings of the Royal Society. B, Biological sciences, 2009-02, Vol.276 (1656), p.389-399

2009

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Effects of elevated circulating cortisol concentrations on maternal behavior in common marmoset monkeys ( Callithrix jacchus )

Psychoneuroendocrinology, 2009-09, Vol.34 (8), p.1222-1234

2009

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Naturally Occurring and Experimentally Induced Rhesus Macaque Models for Polycystic Ovary Syndrome: Translational Gateways to Clinical Application

Medical sciences (Basel), 2019-11, Vol.7 (12), p.107

2019

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Does a compromised placenta contribute to transgenerational transmission of metabolic dysfunction in polycystic ovary syndrome?

Fertility and sterility, 2020-06, Vol.113 (6), p.1165-1166

Abbott, David H.

2020

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Neuronal androgen receptor: Molecular gateway to polycystic ovary syndrome?

Proceedings of the National Academy of Sciences - PNAS, 2017-04, Vol.114 (16), p.4045-4047

Abbott, David H.

2017

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Animal Models to Understand the Etiology and Pathophysiology of Polycystic Ovary Syndrome

Androgens in maternal vascular and placental function: implications for preeclampsia pathogenesis

Epigenetic mechanism underlying the development of polycystic ovary syndrome (PCOS)-like phenotypes in prenatally androgenized rhesus monkeys

Ontogeny of polycystic ovary syndrome and insulin resistance in utero and early childhood

Mechanisms of intergenerational transmission of polycystic ovary syndrome

Hyperandrogenic origins of polycystic ovary syndrome - implications for pathophysiology and therapy

Hyperandrogenism Accompanies Increased Intra-Abdominal Fat Storage in Normal Weight Polycystic Ovary Syndrome Women

Polycystic ovary syndrome as a plausible evolutionary outcome of metabolic adaptation

Early-to-mid gestation fetal testosterone increases right hand 2D:4D finger length ratio in polycystic ovary syndrome-like monkeys

Dexrazoxane Diminishes Doxorubicin-Induced Acute Ovarian Damage and Preserves Ovarian Function and Fecundity in Mice

Translational Insight Into Polycystic Ovary Syndrome (PCOS) From Female Monkeys with PCOS-like Traits

Androgen Receptors in Multiple Organ Systems Provide Molecular Gateways to Polycystic Ovary Syndrome

The marmoset monkey: a multi-purpose preclinical and translational model of human biology and disease

Abnormal infant islet morphology precedes insulin resistance in PCOS-like monkeys

Fetal, infant, adolescent and adult phenotypes of polycystic ovary syndrome in prenatally androgenized female rhesus monkeys

Environmental factors and puberty timing: expert panel research needs

Acute doxorubicin insult in the mouse ovary is cell- and follicle-type dependent

Bortezomib prevents acute doxorubicin ovarian insult and follicle demise, improving the fertility window and pup birth weight in mice

Experimentally Induced Hyperinsulinemia Fails to Induce Polycystic Ovary Syndrome-like Traits in Female Rhesus Macaques

Accelerated Episodic Luteinizing Hormone Release Accompanies Blunted Progesterone Regulation in PCOS-like Female Rhesus Monkeys (Macaca Mulatta) Exposed to Testosterone during Early-to-Mid Gestation

Reproductive skew in female common marmosets: what can proximate mechanisms tell us about ultimate causes?

Effects of elevated circulating cortisol concentrations on maternal behavior in common marmoset monkeys ( Callithrix jacchus )

Naturally Occurring and Experimentally Induced Rhesus Macaque Models for Polycystic Ovary Syndrome: Translational Gateways to Clinical Application

Does a compromised placenta contribute to transgenerational transmission of metabolic dysfunction in polycystic ovary syndrome?

Neuronal androgen receptor: Molecular gateway to polycystic ovary syndrome?

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