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Target Site Delivery and Residence of Nanomedicines: Application of Quantitative Systems Pharmacology

Pharmacological reviews, 2019-04, Vol.71 (2), p.157-169

2019

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Is It Time to Use Modeling of Cellular Transporter Homeostasis to Inform Drug-Drug Interaction Studies: Theoretical Considerations

The AAPS journal, 2021-08, Vol.23 (5), p.102, Article 102

2021

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Innovations and Improvements in Pharmacokinetic Models Based on Physiology

Current drug delivery, 2017-03, Vol.14 (2), p.190

2017

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Quantitative Systems Pharmacology Modeling of Avadomide-Induced Neutropenia Enables Virtual Clinical Dose and Schedule Finding Studies

The AAPS journal, 2021-08, Vol.23 (5), p.103, Article 103

2021

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Correction to: Quantitative Systems Pharmacology Modeling of Avadomide-Induced Neutropenia Enables Virtual Clinical Dose and Schedule Finding Studies

The AAPS journal, 2022-01, Vol.24 (1), p.29-29, Article 29

2022

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Systemic Bioequivalence Is Unlikely to Equal Target Site Bioequivalence for Nanotechnology Oncologic Products

The AAPS journal, 2019-02, Vol.21 (2), p.24-24, Article 24

2019

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Performance of classical and physiologically-based PK-PD modelling for prediction of remifentanil hemodynamic effects

Computer Aided Chemical Engineering, 2017-01, Vol.40, p.2755-2760

2017

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A physiologically based model for tramadol pharmacokinetics in horses

Journal of theoretical biology, 2017-09, Vol.429, p.46-51

2017

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A new approach for pharmacokinetic model application towards personalized medicine

Computer Aided Chemical Engineering, 2016, Vol.38, p.1611-1616

2016

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Enterohepatic Circulation Effect in Physiologically Based Pharmacokinetic Models: The Sorafenib Case

Industrial & engineering chemistry research, 2017-03, Vol.56 (12), p.3156-3166

2017

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A modeling tool for the personalization of pharmacokinetic predictions

Computers & chemical engineering, 2016-08, Vol.91, p.28-37

2016

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Species differences in cellular processing of siRNA‐Lipid complex

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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In Silico Studies to Demonstrate Potential Drug‐Drug Interaction (DDI) By Disrupting Cellular Homeostasis of Organic Anion Transporting Proteins (OATP)

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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A physiologically-based model to predict individual pharmacokinetics and pharmacodynamics of remifentanil

European journal of pharmaceutical sciences, 2018-01, Vol.111, p.20-28

2018

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Definition and validation of a patient-individualized physiologically-based pharmacokinetic model

Computers & chemical engineering, 2016-01, Vol.84, p.394-408

2016

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Nutritional supplementation with branched-chain amino acids in advanced cirrhosis: a double-blind, randomized trial

Gastroenterology (New York, N.Y. 1943), 2003-06, Vol.124 (7), p.1792-1801

2003

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Quantitative Pharmacology of Internalization, Intracellular Trafficking and Gene Silencing of siRNA

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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Rap-536 Induces Reticulocyte Maturation in Wild-Type Mice, Increases Survival of Beta-Thalassemic Reticulocytes, and Increases Red Blood Cells in a Mouse Model of Alpha-Thalassemia

Blood, 2020-11, Vol.136 (Supplement 1), p.18-19

2020

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Engineering approaches in siRNA delivery

International journal of pharmaceutics, 2017-06, Vol.525 (2), p.343-358

2017

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Quantitative Pharmacology to Interrogate Mechanisms of Lipoplex Destabilization by Serum Proteins

The FASEB journal, 2017-04, Vol.31 (S1)

2017

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Clinical Trial on the Efficacy of a New Symbiotic Formulation, Flortec, in Patients With Acute Diarrhea: A Multicenter, Randomized Study in Primary Care

Journal of clinical gastroenterology, 2010-09, Vol.44 Suppl 1 (Supplement 1), p.S35-S41

2010

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Factors associated with poor health-related quality of life of patients with cirrhosis

Gastroenterology (New York, N.Y. 1943), 2001-01, Vol.120 (1), p.170-178

2001

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Sorafenib in Mice – A Pharmacokinetic Study

Chemical engineering transactions, 2015-01, Vol.43

2015

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Clinical Trial on the Efficacy of a New Symbiotic Formulation, Flortec, in Patients With Irritable Bowel Syndrome: A Multicenter, Randomized Study

Journal of clinical gastroenterology, 2008-09, Vol.42 Suppl 3, Part 2 (8SUP), p.S218-S223

2008

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A PSE approach to patient-individualized physiologically-based pharmacokinetic modeling

Computer Aided Chemical Engineering, 2015, Vol.37, p.77-84

2015

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Target Site Delivery and Residence of Nanomedicines: Application of Quantitative Systems Pharmacology

Is It Time to Use Modeling of Cellular Transporter Homeostasis to Inform Drug-Drug Interaction Studies: Theoretical Considerations

Innovations and Improvements in Pharmacokinetic Models Based on Physiology

Quantitative Systems Pharmacology Modeling of Avadomide-Induced Neutropenia Enables Virtual Clinical Dose and Schedule Finding Studies

Correction to: Quantitative Systems Pharmacology Modeling of Avadomide-Induced Neutropenia Enables Virtual Clinical Dose and Schedule Finding Studies

Systemic Bioequivalence Is Unlikely to Equal Target Site Bioequivalence for Nanotechnology Oncologic Products

Performance of classical and physiologically-based PK-PD modelling for prediction of remifentanil hemodynamic effects

A physiologically based model for tramadol pharmacokinetics in horses

A new approach for pharmacokinetic model application towards personalized medicine

Enterohepatic Circulation Effect in Physiologically Based Pharmacokinetic Models: The Sorafenib Case

A modeling tool for the personalization of pharmacokinetic predictions

Species differences in cellular processing of siRNA‐Lipid complex

In Silico Studies to Demonstrate Potential Drug‐Drug Interaction (DDI) By Disrupting Cellular Homeostasis of Organic Anion Transporting Proteins (OATP)

A physiologically-based model to predict individual pharmacokinetics and pharmacodynamics of remifentanil

Definition and validation of a patient-individualized physiologically-based pharmacokinetic model

Nutritional supplementation with branched-chain amino acids in advanced cirrhosis: a double-blind, randomized trial

Quantitative Pharmacology of Internalization, Intracellular Trafficking and Gene Silencing of siRNA

Rap-536 Induces Reticulocyte Maturation in Wild-Type Mice, Increases Survival of Beta-Thalassemic Reticulocytes, and Increases Red Blood Cells in a Mouse Model of Alpha-Thalassemia

Engineering approaches in siRNA delivery

Quantitative Pharmacology to Interrogate Mechanisms of Lipoplex Destabilization by Serum Proteins

Clinical Trial on the Efficacy of a New Symbiotic Formulation, Flortec, in Patients With Acute Diarrhea: A Multicenter, Randomized Study in Primary Care

Factors associated with poor health-related quality of life of patients with cirrhosis

Sorafenib in Mice – A Pharmacokinetic Study

Clinical Trial on the Efficacy of a New Symbiotic Formulation, Flortec, in Patients With Irritable Bowel Syndrome: A Multicenter, Randomized Study

A PSE approach to patient-individualized physiologically-based pharmacokinetic modeling

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