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Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis

Nature communications, 2016-11, Vol.7 (1), p.13457-13457, Article 13457

2016

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Glucose‐regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders

IUBMB life, 2021-06, Vol.73 (6), p.843-854

2021

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Decreased Endogenous Production of Hydrogen Sulfide Accelerates Atherosclerosis

Circulation (New York, N.Y.), 2013-06, Vol.127 (25), p.2523-2534

2013

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Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue

The European respiratory journal, 2020-09, Vol.56 (3), p.2001123

2020

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Endoplasmic Reticulum Stress and Lipid Metabolism: Mechanisms and Therapeutic Potential

Biochemistry Research International, 2012-01, Vol.2012, p.841362-13

2012

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Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance

Nature communications, 2022-02, Vol.13 (1), p.770-770, Article 770

2022

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Reduced plasma GDF10 levels are positively associated with cholesterol impairment and childhood obesity

Scientific reports, 2024-01, Vol.14 (1), p.1805-1805, Article 1805

2024

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The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response[S]

Journal of lipid research, 2009-12, Vol.50 (12), p.2486-2501

2009

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Interstitial Cell Remodeling Promotes Aberrant Adipogenesis in Dystrophic Muscles

Cell reports (Cambridge), 2020-05, Vol.31 (5), p.107597-107597, Article 107597

2020

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GRP78 and CHOP modulate macrophage apoptosis and the development of bleomycin-induced pulmonary fibrosis

The Journal of pathology, 2016-08, Vol.239 (4), p.411-425

2016

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Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration, and attenuates atherosclerosis in ApoE knockout mice

The Journal of biological chemistry, 2018-09, Vol.293 (38), p.14689-14706

2018

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TDAG51 induces renal interstitial fibrosis through modulation of TGF-β receptor 1 in chronic kidney disease

Cell death & disease, 2021-10, Vol.12 (10), p.921-921, Article 921

2021

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Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism

The Journal of biological chemistry, 2017-01, Vol.292 (4), p.1510-1523

2017

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A Metabolic Enhancer Protects against Diet-Induced Obesity and Liver Steatosis and Corrects a Pro-Atherogenic Serum Profile in Mice

Nutrients, 2023-05, Vol.15 (10), p.2410

2023

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Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E-deficient mice

Circulation (New York, N.Y.), 2005-04, Vol.111 (14), p.1814-1821

2005

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Salicylate improves macrophage cholesterol homeostasis via activation of Ampk

Journal of lipid research, 2015-05, Vol.56 (5), p.1025-1033

2015

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Fatal attractions that trigger inflammation and drive atherosclerotic disease

European journal of clinical investigation, 2024-05, Vol.54 (5), p.e14169-e14169

2024

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ER stress contributes to renal proximal tubule injury by increasing SREBP-2-mediated lipid accumulation and apoptotic cell death

American journal of physiology. Renal physiology, 2012-07, Vol.303 (2), p.F266-F278

2012

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Extensive diet-induced atherosclerosis in scavenger receptor class B type 1-deficient mice is associated with substantial leukocytosis and elevated vascular cell adhesion molecule-1 expression in coronary artery endothelium

Frontiers in physiology, 2023-01, Vol.13, p.1023397-1023397

2023

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Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3

Journal of cell science, 2005-01, Vol.118 (Pt 1), p.89-99

2005

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Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice

JHEP reports, 2019-12, Vol.1 (6), p.418-429

2019

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The Emerging Roles of Intracellular PCSK9 and Their Implications in Endoplasmic Reticulum Stress and Metabolic Diseases

Metabolites, 2022-02, Vol.12 (3), p.215

2022

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Cystathionine Protects against Endoplasmic Reticulum Stress-induced Lipid Accumulation, Tissue Injury, and Apoptotic Cell Death

The Journal of biological chemistry, 2012-09, Vol.287 (38), p.31994-32005

2012

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Autoantibodies against the cell surface–associated chaperone GRP78 stimulate tumor growth via tissue factor

The Journal of biological chemistry, 2017-12, Vol.292 (51), p.21180-21192

2017

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Endoplasmic reticulum stress and lipid dysregulation

Expert reviews in molecular medicine, 2011-02, Vol.13, p.e4-e4, Article e4

2011

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Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis

Glucose‐regulated protein (GRP78) is an important cell surface receptor for viral invasion, cancers, and neurological disorders

Decreased Endogenous Production of Hydrogen Sulfide Accelerates Atherosclerosis

Gene expression and in situ protein profiling of candidate SARS-CoV-2 receptors in human airway epithelial cells and lung tissue

Endoplasmic Reticulum Stress and Lipid Metabolism: Mechanisms and Therapeutic Potential

Caffeine blocks SREBP2-induced hepatic PCSK9 expression to enhance LDLR-mediated cholesterol clearance

Reduced plasma GDF10 levels are positively associated with cholesterol impairment and childhood obesity

The chemical chaperone 4-phenylbutyrate inhibits adipogenesis by modulating the unfolded protein response[S]

Interstitial Cell Remodeling Promotes Aberrant Adipogenesis in Dystrophic Muscles

GRP78 and CHOP modulate macrophage apoptosis and the development of bleomycin-induced pulmonary fibrosis

Sialidase down-regulation reduces non-HDL cholesterol, inhibits leukocyte transmigration, and attenuates atherosclerosis in ApoE knockout mice

TDAG51 induces renal interstitial fibrosis through modulation of TGF-β receptor 1 in chronic kidney disease

Endoplasmic Reticulum Stress and Ca2+ Depletion Differentially Modulate the Sterol Regulatory Protein PCSK9 to Control Lipid Metabolism

A Metabolic Enhancer Protects against Diet-Induced Obesity and Liver Steatosis and Corrects a Pro-Atherogenic Serum Profile in Mice

Activation of the unfolded protein response occurs at all stages of atherosclerotic lesion development in apolipoprotein E-deficient mice

Salicylate improves macrophage cholesterol homeostasis via activation of Ampk

Fatal attractions that trigger inflammation and drive atherosclerotic disease

ER stress contributes to renal proximal tubule injury by increasing SREBP-2-mediated lipid accumulation and apoptotic cell death

Extensive diet-induced atherosclerosis in scavenger receptor class B type 1-deficient mice is associated with substantial leukocytosis and elevated vascular cell adhesion molecule-1 expression in coronary artery endothelium

Valproate protects cells from ER stress-induced lipid accumulation and apoptosis by inhibiting glycogen synthase kinase-3

Pcsk9 knockout exacerbates diet-induced non-alcoholic steatohepatitis, fibrosis and liver injury in mice

The Emerging Roles of Intracellular PCSK9 and Their Implications in Endoplasmic Reticulum Stress and Metabolic Diseases

Cystathionine Protects against Endoplasmic Reticulum Stress-induced Lipid Accumulation, Tissue Injury, and Apoptotic Cell Death

Autoantibodies against the cell surface–associated chaperone GRP78 stimulate tumor growth via tissue factor

Endoplasmic reticulum stress and lipid dysregulation

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