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Succinate is an inflammatory signal that induces IL-1β through HIF-1α

Nature (London), 2013-04, Vol.496 (7444), p.238-242

2013

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Interleukin 1 signal transduction--current concepts and relevance to periodontitis

Journal of dental research, 2001-02, Vol.80 (2), p.400-407

2001

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Translational control during the acute phase response: Ferritin synthesis in response to interleukin-1

The Journal of biological chemistry, 1990-08, Vol.265 (24), p.14572-14578

1990

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The human prointerleukin 1 beta gene requires DNA sequences both proximal and distal to the transcription start site for tissue-specific induction

Molecular and Cellular Biology, 1993-03, Vol.13 (3), p.1332-1344

1993

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Negative Cross-Talk between Hematopoietic Regulators: GATA Proteins Repress PU.1

Proceedings of the National Academy of Sciences - PNAS, 1999-07, Vol.96 (15), p.8705-8710

1999

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Interleukin 1 Activates STAT3/Nuclear Factor-κB Cross-talk via a Unique TRAF6- and p65-dependent Mechanism

The Journal of biological chemistry, 2004-01, Vol.279 (3), p.1768-1776

2004

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The Interleukin 1 Receptor: Ligand Interactions and Signal Transduction

Cytokine & growth factor reviews, 1998-12, Vol.9 (3), p.221-237

Auron, Philip E.

1998

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Transcription factors NF-IL6 and CREB recognize a common essential site in the human prointerleukin 1 beta gene

Molecular and Cellular Biology, 1994-11, Vol.14 (11), p.7285-7297

1994

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Monocyte expression of the human prointerleukin 1 beta gene (IL1B) is dependent on promoter sequences which bind the hematopoietic transcription factor Spi-1/PU.1

Molecular and Cellular Biology, 1995-01, Vol.15 (1), p.59-68

1995

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Heat Shock Factor 1 Represses Transcription of the IL-1β Gene through Physical Interaction with the Nuclear Factor of Interleukin 6

The Journal of biological chemistry, 2002-04, Vol.277 (14), p.11802-11810

2002

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Nucleotide Sequence of Human Monocyte Interleukin 1 Precursor cDNA

Proceedings of the National Academy of Sciences - PNAS, 1984-12, Vol.81 (24), p.7907-7911

1984

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Mouse beta-globin DNA-binding protein B1 is identical to a proto-oncogene, the transcription factor Spi-1/PU.1, and is restricted in expression to hematopoietic cells and the testis

Molecular and Cellular Biology, 1993-05, Vol.13 (5), p.2929-2941

1993

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Heat Shock Factor 1 Represses Ras-induced Transcriptional Activation of the c-fos Gene

The Journal of biological chemistry, 1997-10, Vol.272 (43), p.26803-26806

1997

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Egr-1 Mediates Transcriptional Repression of COL2A1 Promoter Activity by Interleukin-1 beta

The Journal of biological chemistry, 2003-05, Vol.278 (20), p.17688-17700

2003

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Interleukin-1: a gene expression system regulated at multiple levels

European cytokine network (Montrouge), 1994-11, Vol.5 (6), p.573-592

1994

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Cloning, characterization, and expression of a human calcitonin receptor from an ovarian carcinoma cell line

The Journal of clinical investigation, 1992-11, Vol.90 (5), p.1726-1735

1992

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Human pro-IL-1 beta gene expression in monocytic cells is regulated by two distinct pathways

The Journal of immunology (1950), 1988-04, Vol.140 (7), p.2267

1988

Volltextzugriff (PDF)

A novel STAT-like factor mediates lipopolysaccharide, interleukin 1 (IL-1), and IL-6 signaling and recognizes a gamma interferon activation site-like element in the IL1B gene

Molecular and Cellular Biology, 1996-05, Vol.16 (5), p.2183-2194

1996

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Transcriptional regulation of the human prointerleukin 1 beta gene

The Journal of immunology (1950), 1987-06, Vol.138 (11), p.3972

1987

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Multiple biological activities of human recombinant interleukin 1

The Journal of clinical investigation, 1986-06, Vol.77 (6), p.1734-1739

1986

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Autocrine Induction of the Human Pro-IL-1β Gene Promoter by IL-1β in Monocytes

The Journal of immunology (1950), 2002-02, Vol.168 (4), p.1984-1991

2002

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NF-IL6 (C/EBPβ) Vigorously Activates il1b Gene Expression via a Spi-1 (PU.1) Protein-Protein Tether

The Journal of biological chemistry, 2000-07, Vol.275 (28), p.21272-21277

2000

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Studies on the molecular nature of human interleukin 1

The Journal of immunology (1950), 1987-03, Vol.138 (5), p.1447

1987

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A point mutation uncouples human interleukin-1 beta biological activity and receptor binding

The Journal of biological chemistry, 1990-04, Vol.265 (11), p.5922-5925

1990

Volltextzugriff (PDF)

The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon-gamma-mediated inhibition in human chondrocytes: requirement for Stat1 alpha, Jak1 and Jak2

Biochemical journal, 2003-01, Vol.369 (Pt 1), p.103-115

2003

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Succinate is an inflammatory signal that induces IL-1β through HIF-1α

Interleukin 1 signal transduction--current concepts and relevance to periodontitis

Translational control during the acute phase response: Ferritin synthesis in response to interleukin-1

The human prointerleukin 1 beta gene requires DNA sequences both proximal and distal to the transcription start site for tissue-specific induction

Negative Cross-Talk between Hematopoietic Regulators: GATA Proteins Repress PU.1

Interleukin 1 Activates STAT3/Nuclear Factor-κB Cross-talk via a Unique TRAF6- and p65-dependent Mechanism

The Interleukin 1 Receptor: Ligand Interactions and Signal Transduction

Transcription factors NF-IL6 and CREB recognize a common essential site in the human prointerleukin 1 beta gene

Monocyte expression of the human prointerleukin 1 beta gene (IL1B) is dependent on promoter sequences which bind the hematopoietic transcription factor Spi-1/PU.1

Heat Shock Factor 1 Represses Transcription of the IL-1β Gene through Physical Interaction with the Nuclear Factor of Interleukin 6

Nucleotide Sequence of Human Monocyte Interleukin 1 Precursor cDNA

Mouse beta-globin DNA-binding protein B1 is identical to a proto-oncogene, the transcription factor Spi-1/PU.1, and is restricted in expression to hematopoietic cells and the testis

Heat Shock Factor 1 Represses Ras-induced Transcriptional Activation of the c-fos Gene

Egr-1 Mediates Transcriptional Repression of COL2A1 Promoter Activity by Interleukin-1 beta

Interleukin-1: a gene expression system regulated at multiple levels

Cloning, characterization, and expression of a human calcitonin receptor from an ovarian carcinoma cell line

Human pro-IL-1 beta gene expression in monocytic cells is regulated by two distinct pathways

A novel STAT-like factor mediates lipopolysaccharide, interleukin 1 (IL-1), and IL-6 signaling and recognizes a gamma interferon activation site-like element in the IL1B gene

Transcriptional regulation of the human prointerleukin 1 beta gene

Multiple biological activities of human recombinant interleukin 1

Autocrine Induction of the Human Pro-IL-1β Gene Promoter by IL-1β in Monocytes

NF-IL6 (C/EBPβ) Vigorously Activates il1b Gene Expression via a Spi-1 (PU.1) Protein-Protein Tether

Studies on the molecular nature of human interleukin 1

A point mutation uncouples human interleukin-1 beta biological activity and receptor binding

The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon-gamma-mediated inhibition in human chondrocytes: requirement for Stat1 alpha, Jak1 and Jak2

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