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Contemporary Accounts in Drug Discovery and Development

Second edition., 2022

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Discovery of a Novel Class of Orally Active Antifungal β-1,3-d-Glucan Synthase Inhibitors

Antimicrobial Agents and Chemotherapy, 2011-11, Vol.55 (11), p.5099-5106

2011

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Case Studies in Modern Drug Discovery and Development

1. Aufl., 2012

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Discovery of novel quinoline carboxylic acid series as DGAT1 inhibitors

Bioorganic & medicinal chemistry letters, 2014-04, Vol.24 (7), p.1790-1794

2014

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Bicyclic and tricyclic heterocycle derivatives as histamine H3 receptor antagonists for the treatment of obesity

Bioorganic & medicinal chemistry letters, 2013-11, Vol.23 (21), p.6004-6009

2013

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Discovery of oral and inhaled PDE4 inhibitors

Bioorganic & medicinal chemistry letters, 2013-10, Vol.23 (20), p.5528-5532

2013

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Synthesis and SAR studies of benzimidazolone derivatives as histamine H3-receptor antagonists

Bioorganic & medicinal chemistry letters, 2013-11, Vol.23 (21), p.6001-6003

2013

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Synthesis and structure-activity relationships of 2-(1,4'-bipiperidin-1'-yl) thiazolopyridine as H3 receptor antagonists

Bioorganic & medicinal chemistry letters, 2009-11, Vol.19 (21), p.6176-6180

2009

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Lead optimization of a pyridine-carboxamide series as DGAT-1 inhibitors

Bioorganic & medicinal chemistry letters, 2013-02, Vol.23 (4), p.985-988

2013

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The synthesis and structure–activity relationship of pyridazinones as glucan synthase inhibitors

Bioorganic & medicinal chemistry letters, 2011-03, Vol.21 (6), p.1819-1822

2011

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Lead optimization of a sulfonylurea-based piperazine pyridazinone series of glucan synthase inhibitors

Bioorganic & medicinal chemistry letters, 2012-07, Vol.22 (14), p.4896-4899

2012

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The optimization of pyridazinone series of glucan synthase inhibitors

Bioorganic & medicinal chemistry letters, 2012-08, Vol.22 (16), p.5268-5271

2012

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Strong Antimicrobial Activity of Hydroxamic Acids and Newly Synthesized Derivatives

The FASEB journal, 2020-04, Vol.34 (S1), p.1-1

2020

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Discovery of a Potent Thiadiazole Class of Histamine H3 Receptor Antagonist for the Treatment of Diabetes

ACS medicinal chemistry letters, 2012-03, Vol.3 (3), p.198-202

2012

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Palladium-catalyzed Negishi α-arylation of alkylsulfones

Tetrahedron letters, 2010-02, Vol.51 (6), p.939-941

2010

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Synthesis and structure–activity relationships of 2-(1,4′-bipiperidin-1′-yl)thiazolopyridine as H 3 receptor antagonists

Bioorganic & medicinal chemistry letters, 2009-11, Vol.19 (21), p.6176-6180

2009

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Discovery of a Potent Thiadiazole Class of Histamine H 3 Receptor Antagonist for the Treatment of Diabetes

ACS medicinal chemistry letters, 2012-03, Vol.3 (3), p.198-202

2012

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Pharmacological Characterization of a Novel α 2C -Adrenoceptor Agonist N -[3,4-dihydro-4-(1 H -imidazol-4-ylmethyl)-2 H -1, 4-benzoxazin-6-yl]- N -ethyl- N ′-methylurea (Compound A)

The Journal of pharmacology and experimental therapeutics, 2011-04, Vol.337 (1), p.256-266

2011

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Selective benzylic lithiation of N-Boc-2-phenylpiperidine and pyrrolidine: expedient synthesis of a 2,2-disubstituted piperidine NK1 antagonist

Tetrahedron letters, 2005-10, Vol.46 (44), p.7653-7656

2005

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Synthesis and structure-activity relationships of 2-(1,4'-bipiperidin-1'-yl)thiazolopyridine as H sub(3) receptor antagonists

Bioorganic & medicinal chemistry letters, 2009-11, Vol.19 (21), p.6176-6180

2009

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Finding Cures for Alzheimer's Disease

Contemporary Accounts in Drug Discovery and Development, 2022, p.51-83

2022

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Advanced Computational Modeling Accelerating Small‐Molecule Drug Discovery

Contemporary Accounts in Drug Discovery and Development, 2022, p.9-25

2022

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Discovery of HTL26119

Contemporary Accounts in Drug Discovery and Development, 2022, p.179-200

2022

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Entrepreneurial Drug Hunter

Contemporary Accounts in Drug Discovery and Development, 2022, p.273-292

2022

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Accelerating Drug Discovery and Development

Contemporary Accounts in Drug Discovery and Development, 2022, p.385-420

2022

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Contemporary Accounts in Drug Discovery and Development

Discovery of a Novel Class of Orally Active Antifungal β-1,3-d-Glucan Synthase Inhibitors

Case Studies in Modern Drug Discovery and Development

Discovery of novel quinoline carboxylic acid series as DGAT1 inhibitors

Bicyclic and tricyclic heterocycle derivatives as histamine H3 receptor antagonists for the treatment of obesity

Discovery of oral and inhaled PDE4 inhibitors

Synthesis and SAR studies of benzimidazolone derivatives as histamine H3-receptor antagonists

Synthesis and structure-activity relationships of 2-(1,4'-bipiperidin-1'-yl) thiazolopyridine as H3 receptor antagonists

Lead optimization of a pyridine-carboxamide series as DGAT-1 inhibitors

The synthesis and structure–activity relationship of pyridazinones as glucan synthase inhibitors

Lead optimization of a sulfonylurea-based piperazine pyridazinone series of glucan synthase inhibitors

The optimization of pyridazinone series of glucan synthase inhibitors

Strong Antimicrobial Activity of Hydroxamic Acids and Newly Synthesized Derivatives

Discovery of a Potent Thiadiazole Class of Histamine H3 Receptor Antagonist for the Treatment of Diabetes

Palladium-catalyzed Negishi α-arylation of alkylsulfones

Synthesis and structure–activity relationships of 2-(1,4′-bipiperidin-1′-yl)thiazolopyridine as H 3 receptor antagonists

Discovery of a Potent Thiadiazole Class of Histamine H 3 Receptor Antagonist for the Treatment of Diabetes

Pharmacological Characterization of a Novel α 2C -Adrenoceptor Agonist N -[3,4-dihydro-4-(1 H -imidazol-4-ylmethyl)-2 H -1, 4-benzoxazin-6-yl]- N -ethyl- N ′-methylurea (Compound A)

Selective benzylic lithiation of N-Boc-2-phenylpiperidine and pyrrolidine: expedient synthesis of a 2,2-disubstituted piperidine NK1 antagonist

Synthesis and structure-activity relationships of 2-(1,4'-bipiperidin-1'-yl)thiazolopyridine as H sub(3) receptor antagonists

Finding Cures for Alzheimer's Disease

Advanced Computational Modeling Accelerating Small‐Molecule Drug Discovery

Discovery of HTL26119

Entrepreneurial Drug Hunter

Accelerating Drug Discovery and Development

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