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Getting a grip with kirigami

Nature materials, 2021-08, Vol.20 (8), p.1043-1044

2021

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In-depth quantitative analysis and comparison of the human hepatocyte and hepatoma cell line HepG2 proteomes

Journal of proteomics, 2016-03, Vol.136, p.234-247

2016

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Determination of drug permeability and prediction of drug absorption in Caco-2 monolayers

Nature protocols, 2007-09, Vol.2 (9), p.2111-2119

2007

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Classification of Inhibitors of Hepatic Organic Anion Transporting Polypeptides (OATPs): Influence of Protein Expression on Drug–Drug Interactions

Journal of medicinal chemistry, 2012-05, Vol.55 (10), p.4740-4763

2012

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CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil

Nature communications, 2016-03, Vol.7 (1), p.11040-11040, Article 11040

2016

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Structural and conformational determinants of macrocycle cell permeability

Nature chemical biology, 2016-12, Vol.12 (12), p.1065-1074

2016

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Coexistence of passive and carrier-mediated processes in drug transport

Nature reviews. Drug discovery, 2010-08, Vol.9 (8), p.597-614

2010

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Cell‐type‐resolved proteomic analysis of the human liver

Liver international, 2020-07, Vol.40 (7), p.1770-1780

2020

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Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy

Nature communications, 2020-03, Vol.11 (1), p.1308-10, Article 1308

2020

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Toward a Consensus on Applying Quantitative Liquid Chromatography‐Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper

Clinical pharmacology and therapeutics, 2019-09, Vol.106 (3), p.525-543

2019

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Hepatic uptake of atorvastatin: influence of variability in transporter expression on uptake clearance and drug-drug interactions

Drug metabolism and disposition, 2014-07, Vol.42 (7), p.1210-1218

2014

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Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery

Proceedings of the National Academy of Sciences - PNAS, 2017-07, Vol.114 (30), p.E6231-E6239

2017

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Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines

Drug metabolism and disposition, 2007-08, Vol.35 (8), p.1333-1340

2007

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Early pharmaceutical profiling to predict oral drug absorption: Current status and unmet needs

European journal of pharmaceutical sciences, 2014-06, Vol.57, p.173-199

2014

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Subcellular fractionation of human liver reveals limits in global proteomic quantification from isolated fractions

Analytical biochemistry, 2016-09, Vol.509, p.82-88

2016

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In vitro models to determine human intestinal presystemic metabolism after oral dosing

Drug metabolism and pharmacokinetics, 2024-04, Vol.55, p.100830, Article 100830

2024

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Variability in Mass Spectrometry-based Quantification of Clinically Relevant Drug Transporters and Drug Metabolizing Enzymes

Molecular pharmaceutics, 2017-09, Vol.14 (9), p.3142-3151

2017

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Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues

Advanced drug delivery reviews, 2016-11, Vol.106 (Pt B), p.256-276

2016

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Identification of Novel Specific and General Inhibitors of the Three Major Human ATP-Binding Cassette Transporters P-gp, BCRP and MRP2 Among Registered Drugs

Pharmaceutical research, 2009-08, Vol.26 (8), p.1816-1831

2009

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OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids

Scientific reports, 2024-07, Vol.14 (1), p.17334-13, Article 17334

2024

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Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations

Scientific reports, 2019-04, Vol.9 (1), p.5850, Article 5850

2019

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A new opening for orally taken peptide drugs

Nature biomedical engineering, 2020-01, Vol.4 (1), p.12-13

2020

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Hepatocyte size fractionation allows dissection of human liver zonation

Journal of cellular physiology, 2021-08, Vol.236 (8), p.5885-5894

2021

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A simple approach for restoration of differentiation and function in cryopreserved human hepatocytes

Archives of toxicology, 2019-03, Vol.93 (3), p.819-829

2019

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In Vitro and In Silico Strategies to Identify OATP1B1 Inhibitors and Predict Clinical Drug–Drug Interactions

Pharmaceutical research, 2012-02, Vol.29 (2), p.411-426

2012

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Getting a grip with kirigami

In-depth quantitative analysis and comparison of the human hepatocyte and hepatoma cell line HepG2 proteomes

Determination of drug permeability and prediction of drug absorption in Caco-2 monolayers

Classification of Inhibitors of Hepatic Organic Anion Transporting Polypeptides (OATPs): Influence of Protein Expression on Drug–Drug Interactions

CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil

Structural and conformational determinants of macrocycle cell permeability

Coexistence of passive and carrier-mediated processes in drug transport

Cell‐type‐resolved proteomic analysis of the human liver

Exploiting loss of heterozygosity for allele-selective colorectal cancer chemotherapy

Toward a Consensus on Applying Quantitative Liquid Chromatography‐Tandem Mass Spectrometry Proteomics in Translational Pharmacology Research: A White Paper

Hepatic uptake of atorvastatin: influence of variability in transporter expression on uptake clearance and drug-drug interactions

Prediction of intracellular exposure bridges the gap between target- and cell-based drug discovery

Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines

Early pharmaceutical profiling to predict oral drug absorption: Current status and unmet needs

Subcellular fractionation of human liver reveals limits in global proteomic quantification from isolated fractions

In vitro models to determine human intestinal presystemic metabolism after oral dosing

Variability in Mass Spectrometry-based Quantification of Clinically Relevant Drug Transporters and Drug Metabolizing Enzymes

Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues

Identification of Novel Specific and General Inhibitors of the Three Major Human ATP-Binding Cassette Transporters P-gp, BCRP and MRP2 Among Registered Drugs

OCT1 (SLC22A1) transporter kinetics and regulation in primary human hepatocyte 3D spheroids

Improved predictions of time-dependent drug-drug interactions by determination of cytosolic drug concentrations

A new opening for orally taken peptide drugs

Hepatocyte size fractionation allows dissection of human liver zonation

A simple approach for restoration of differentiation and function in cryopreserved human hepatocytes

In Vitro and In Silico Strategies to Identify OATP1B1 Inhibitors and Predict Clinical Drug–Drug Interactions

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