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Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues

Advanced drug delivery reviews, 2016-11, Vol.106 (Pt B), p.256-276

2016

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CRISPR-Cas9: A New Addition to the Drug Metabolism and Disposition Tool Box

Drug metabolism and disposition, 2018-11, Vol.46 (11), p.1776-1786

2018

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Caco-2 monolayers in experimental and theoretical predictions of drug transport

Advanced drug delivery reviews, 2001-03, Vol.46 (1), p.27-43

2001

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S-01-02 In vitro ADME assays to inform IVIVE-PBK modelling and simulation

Toxicology letters, 2022-09, Vol.368, p.S14

Artursson, P.

2022

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A Comparative Analysis of Cytochrome P450 Activities in Paired Liver and Small Intestinal Samples from Patients with Obesity

Drug metabolism and disposition, 2020-01, Vol.48 (1), p.8-17

2020

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Mechanistic Modeling of Pitavastatin Disposition in Sandwich-Cultured Human Hepatocytes: A Proteomics-Informed Bottom-Up Approach

Drug metabolism and disposition, 2016-04, Vol.44 (4), p.505-516

2016

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Computational Prospecting for Drug-Transporter Interactions

Clinical pharmacology and therapeutics, 2013-07, Vol.94 (1), p.30-32

2013

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Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

Biochemical and biophysical research communications, 1991-03, Vol.175 (3), p.880-885

1991

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Experimental and Computational Screening Models for the Prediction of Intestinal Drug Absorption

Journal of medicinal chemistry, 2001-06, Vol.44 (12), p.1927-1937

2001

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Proteome deconvolution of liver biopsies reveals hepatic cell composition as an important marker of fibrosis

Computational and structural biotechnology journal, 2023-01, Vol.21, p.4361-4369

2023

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Relationship between the physical shape and the efficiency of oligomeric chitosan as a gene delivery system in vitro and in vivo

The journal of gene medicine, 2003-02, Vol.5 (2), p.130-141

2003

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Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers

Gene therapy, 2004-10, Vol.11 (19), p.1441-1452

2004

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Genotype-dependent effects of inhibitors of the organic cation transporter, OCT1: predictions of metformin interactions

The pharmacogenomics journal, 2011-12, Vol.11 (6), p.400-411

2011

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Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo

Gene therapy, 2001-07, Vol.8 (14), p.1108-1121

2001

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Experimental and computational screening models for prediction of aqueous drug solubility

Pharmaceutical research, 2002-02, Vol.19 (2), p.182-188

2002

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Transport of lipophilic drug molecules in a new mucus-secreting cell culture model based on HT29-MTX cells

Pharmaceutical research, 2001-08, Vol.18 (8), p.1138-1145

2001

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Polar molecular surface properties predict the intestinal absorption of drugs in humans

Pharmaceutical research, 1997, Vol.14 (5), p.568-571

1997

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Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond

Pharmaceutical research, 1997-12, Vol.14 (12), p.1655-1658

1997

Volltextzugriff (PDF)

The value of selected in vitro and in silico methods to predict acute oral toxicity in a regulatory context: Results from the European Project ACuteTox

Toxicology in vitro, 2013-06, Vol.27 (4), p.1357-1376

2013

Volltextzugriff (PDF)

Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2)

Pharmaceutical research, 1994-09, Vol.11 (9), p.1358-1361

1994

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Impact of extracellular protein binding on passive and active drug transport across caco-2 cells

Pharmaceutical research, 2006-02, Vol.23 (2), p.350-359

2006

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Comparison between active and passive drug transport in human intestinal epithelial (caco-2) cells in vitro and human jejunum in vivo

International journal of pharmaceutics, 1996-01, Vol.127 (1), p.103-107

1996

Volltextzugriff (PDF)

PEI - a potent, but not harmless, mucosal immuno-stimulator of mixed T-helper cell response and FasL-mediated cell death in mice

Gene therapy, 2003-09, Vol.10 (18), p.1575-1583

2003

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Mechanisms of absorption enhancement by medium chain fatty acids in intestinal epithelial Caco-2 cell monolayers

The Journal of pharmacology and experimental therapeutics, 1995-11, Vol.275 (2), p.958

1995

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Oral absorption of peptides and nanoparticles across the human intestine: Opportunities, limitations and studies in human tissues

CRISPR-Cas9: A New Addition to the Drug Metabolism and Disposition Tool Box

Caco-2 monolayers in experimental and theoretical predictions of drug transport

Validation and development of MTH1 inhibitors for treatment of cancer

S-01-02 In vitro ADME assays to inform IVIVE-PBK modelling and simulation

A Comparative Analysis of Cytochrome P450 Activities in Paired Liver and Small Intestinal Samples from Patients with Obesity

Mechanistic Modeling of Pitavastatin Disposition in Sandwich-Cultured Human Hepatocytes: A Proteomics-Informed Bottom-Up Approach

Computational Prospecting for Drug-Transporter Interactions

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

Experimental and Computational Screening Models for the Prediction of Intestinal Drug Absorption

Proteome deconvolution of liver biopsies reveals hepatic cell composition as an important marker of fibrosis

Relationship between the physical shape and the efficiency of oligomeric chitosan as a gene delivery system in vitro and in vivo

Improved chitosan-mediated gene delivery based on easily dissociated chitosan polyplexes of highly defined chitosan oligomers

Genotype-dependent effects of inhibitors of the organic cation transporter, OCT1: predictions of metformin interactions

Chitosan as a nonviral gene delivery system. Structure-property relationships and characteristics compared with polyethylenimine in vitro and after lung administration in vivo

Experimental and computational screening models for prediction of aqueous drug solubility

Transport of lipophilic drug molecules in a new mucus-secreting cell culture model based on HT29-MTX cells

Polar molecular surface properties predict the intestinal absorption of drugs in humans

Intestinal drug absorption and metabolism in cell cultures: Caco-2 and beyond

The value of selected in vitro and in silico methods to predict acute oral toxicity in a regulatory context: Results from the European Project ACuteTox

Effect of chitosan on the permeability of monolayers of intestinal epithelial cells (Caco-2)

Impact of extracellular protein binding on passive and active drug transport across caco-2 cells

Comparison between active and passive drug transport in human intestinal epithelial (caco-2) cells in vitro and human jejunum in vivo

PEI - a potent, but not harmless, mucosal immuno-stimulator of mixed T-helper cell response and FasL-mediated cell death in mice

Mechanisms of absorption enhancement by medium chain fatty acids in intestinal epithelial Caco-2 cell monolayers

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