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Pharmacokinetics, pharmacodynamics and safety of QGE031 (ligelizumab), a novel high-affinity anti-IgE antibody, in atopic subjects

Clinical and experimental allergy, 2014-11, Vol.44 (11), p.1371-1385

2014

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Down-regulation of leucocyte immunoglobulin-like receptor expression in the synovium of rheumatoid arthritis patients after treatment with disease-modifying anti-rheumatic drugs

Rheumatology (Oxford, England), 2007-05, Vol.46 (5), p.742-751

2007

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Sorting out the cytokines of asthma

The Journal of experimental medicine, 1996-01, Vol.183 (1), p.1-5

1996

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Chemical mutational analysis of the human glucocorticoid receptor cDNA in glucocorticoid-resistant bronchial asthma

American journal of respiratory cell and molecular biology, 1994-07, Vol.11 (1), p.42

1994

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Effect of the 5-lipoxygenase inhibitor ZD2138 on aspirin-induced asthma

Thorax, 1994-08, Vol.49 (8), p.749-756

1994

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Genomic organization of the human leukocyte immunoglobulin-like receptors within the leukocyte receptor complex on chromosome 19q13.4

Immunogenetics (New York), 2000-07, Vol.51 (8-9), p.659-669

2000

Volltextzugriff (PDF)

IgE-dependent activation of cytokine-primed mouse cultured mast cells induces a delayed phase of prostaglandin D2 generation via prostaglandin endoperoxide synthase-2

The Journal of immunology (1950), 1995-11, Vol.155 (9), p.4445

1995

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Cloning of the gp49B gene of the immunoglobulin superfamily and demonstration that one of its two products is an early-expressed mast cell surface protein originally described as gp49

The Journal of biological chemistry, 1994-03, Vol.269 (11), p.8393-8401

1994

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The Pathobiology of Bronchial Asthma

Advances in Immunology, 1992, Vol.51, p.323-382

1992

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Effect of the 5-lipoxygenase inhibitor ZD2138 on allergen-induced early and late asthmatic responses

Thorax, 1994-08, Vol.49 (8), p.743-748

1994

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Sulphidopeptide leukotrienes in asthma

Clinical science (1979), 1993-05, Vol.84 (5), p.501

1993

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Prostaglandin endoperoxide synthase-1 and -2 couple to different transmembrane stimuli to generate prostaglandin D2 in mouse bone marrow-derived mast cells

The Journal of biological chemistry, 1994-09, Vol.269 (35), p.22269-22275

1994

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The effects of inhaled leukotriene E4 on the airway responsiveness to histamine in subjects with asthma and normal subjects

Journal of allergy and clinical immunology, 1988-10, Vol.82 (4), p.654-660

1988

Volltextzugriff (PDF)

Molecular cloning of gp49, a cell-surface antigen that is preferentially expressed by mouse mast cell progenitors and is a new member of the immunoglobulin superfamily

The Journal of biological chemistry, 1991-08, Vol.266 (24), p.15966-15973

1991

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Effect of dietary supplementation with fish oil lipids on mild asthma

Thorax, 1988-02, Vol.43 (2), p.84-92

1988

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The immediate phase of c-kit ligand stimulation of mouse bone marrow-derived mast cells elicits rapid leukotriene C4 generation through posttranslational activation of cytosolic phospholipase A2 and 5-lipoxygenase

The Journal of experimental medicine, 1995-07, Vol.182 (1), p.197-206

1995

Volltextzugriff (PDF)

Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor

The Journal of immunology (1950), 1997-09, Vol.159 (5), p.2342

1997

Volltextzugriff (PDF)

Characterization of leukotriene B3: comparison of its biological activities with leukotriene B4 and leukotriene B5 in complement receptor enhancement, lysozyme release and chemotaxis of human neutrophils

Clinical science (1979), 1988-05, Vol.74 (5), p.467

1988

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Maturation-related changes in the expression of Fc gamma RII and Fc gamma RIII on mouse mast cells derived in vitro and in vivo

The Journal of immunology (1950), 1990-11, Vol.145 (10), p.3412

1990

Volltextzugriff (PDF)

Regulation of Prostaglandin Endoperoxide Synthase-2 and IL-6 Expression in Mouse Bone Marrow-Derived Mast Cells by Exogenous But Not Endogenous Prostanoids

The Journal of immunology (1950), 2002-02, Vol.168 (3), p.1397-1404

2002

Volltextzugriff (PDF)

Intracellular degradation of Fc gamma RIII in mouse bone marrow culture-derived progenitor mast cells prevents its surface expression and associated function

The Journal of biological chemistry, 1993-01, Vol.268 (2), p.1207-1212

1993

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Low molecular weight group IIA and group V phospholipase A(2) enzymes have different intracellular locations in mouse bone marrow-derived mast cells

The Journal of biological chemistry, 1999-10, Vol.274 (44), p.31476-31484

1999

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Mediator release in aspirin-induced reactions

Journal of allergy and clinical immunology, 1991-12, Vol.88 (6), p.827-829

1991

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A32 NEW ASTHMA THERAPIES: CLINICAL STUDIES: Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of Qge031, A High Affinity Anti-Ige Antibody In Caucasian And Japanese Atopic Subjects

American journal of respiratory and critical care medicine, 2014-01, Vol.189, p.1

2014

Volltextzugriff (PDF)

Aspirin sensitive asthma

Clinical and experimental allergy, 1992-02, Vol.22 (2), p.171-175

1992

Volltextzugriff (PDF)

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Pharmacokinetics, pharmacodynamics and safety of QGE031 (ligelizumab), a novel high-affinity anti-IgE antibody, in atopic subjects

Down-regulation of leucocyte immunoglobulin-like receptor expression in the synovium of rheumatoid arthritis patients after treatment with disease-modifying anti-rheumatic drugs

Sorting out the cytokines of asthma

Chemical mutational analysis of the human glucocorticoid receptor cDNA in glucocorticoid-resistant bronchial asthma

Effect of the 5-lipoxygenase inhibitor ZD2138 on aspirin-induced asthma

Genomic organization of the human leukocyte immunoglobulin-like receptors within the leukocyte receptor complex on chromosome 19q13.4

IgE-dependent activation of cytokine-primed mouse cultured mast cells induces a delayed phase of prostaglandin D2 generation via prostaglandin endoperoxide synthase-2

Cloning of the gp49B gene of the immunoglobulin superfamily and demonstration that one of its two products is an early-expressed mast cell surface protein originally described as gp49

The Pathobiology of Bronchial Asthma

Effect of the 5-lipoxygenase inhibitor ZD2138 on allergen-induced early and late asthmatic responses

Sulphidopeptide leukotrienes in asthma

Prostaglandin endoperoxide synthase-1 and -2 couple to different transmembrane stimuli to generate prostaglandin D2 in mouse bone marrow-derived mast cells

The effects of inhaled leukotriene E4 on the airway responsiveness to histamine in subjects with asthma and normal subjects

Molecular cloning of gp49, a cell-surface antigen that is preferentially expressed by mouse mast cell progenitors and is a new member of the immunoglobulin superfamily

Effect of dietary supplementation with fish oil lipids on mild asthma

The immediate phase of c-kit ligand stimulation of mouse bone marrow-derived mast cells elicits rapid leukotriene C4 generation through posttranslational activation of cytosolic phospholipase A2 and 5-lipoxygenase

Molecular identification of a novel family of human Ig superfamily members that possess immunoreceptor tyrosine-based inhibition motifs and homology to the mouse gp49B1 inhibitory receptor

Characterization of leukotriene B3: comparison of its biological activities with leukotriene B4 and leukotriene B5 in complement receptor enhancement, lysozyme release and chemotaxis of human neutrophils

Maturation-related changes in the expression of Fc gamma RII and Fc gamma RIII on mouse mast cells derived in vitro and in vivo

Regulation of Prostaglandin Endoperoxide Synthase-2 and IL-6 Expression in Mouse Bone Marrow-Derived Mast Cells by Exogenous But Not Endogenous Prostanoids

Intracellular degradation of Fc gamma RIII in mouse bone marrow culture-derived progenitor mast cells prevents its surface expression and associated function

Low molecular weight group IIA and group V phospholipase A(2) enzymes have different intracellular locations in mouse bone marrow-derived mast cells

Mediator release in aspirin-induced reactions

A32 NEW ASTHMA THERAPIES: CLINICAL STUDIES: Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of Qge031, A High Affinity Anti-Ige Antibody In Caucasian And Japanese Atopic Subjects

Aspirin sensitive asthma

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