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Hepatic De Novo Lipogenesis Is Present in Liver-Specific ACC1-Deficient Mice

Molecular and Cellular Biology, 2007-03, Vol.27 (5), p.1881-1888

2007

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Acyl-CoA:cholesterol acyltransferase inhibition reduces atherosclerosis in apolipoprotein E-deficient mice

Circulation (New York, N.Y.), 2001-05, Vol.103 (21), p.2604-2609

2001

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5,5-Dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione, a potent inhibitor for mammalian elongase of long-chain fatty acids family 6: examination of its potential utility as a pharmacological tool

The Journal of pharmacology and experimental therapeutics, 2009-07, Vol.330 (1), p.249

2009

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Synthesis and evaluation of a novel 2-azabicyclo[2.2.2]octane class of long chain fatty acid elongase 6 (ELOVL6) inhibitors

Bioorganic & medicinal chemistry, 2009-08, Vol.17 (15), p.5639-5647

2009

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Postprandial hyperlipidemia in streptozotocin-induced diabetic rats is due to abnormal increase in intestinal acyl coenzyme A:cholesterol acyltransferase activity

Arteriosclerosis, thrombosis, and vascular biology, 2000-01, Vol.20 (1), p.171-178

2000

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Direct effect of an acyl‐CoA:cholesterol acyltransferase inhibitor, F‐1394, on atherosclerosis in apolipoprotein E and low density lipoprotein receptor double knockout mice

British journal of pharmacology, 2001-08, Vol.133 (7), p.1005-1012

2001

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Effect of F-1394, an acyl-CoA:cholesterol acyltransferase inhibitor, on atherosclerosis induced by high cholesterol diet in rabbits

Atherosclerosis, 2001-09, Vol.158 (1), p.139-145

2001

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Role of MGAT2 and DGAT1 in the release of gut peptides after triglyceride ingestion

Biochemical and biophysical research communications, 2009-12, Vol.390 (3), p.377-381

2009

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ACAT inhibitor F-1394 prevents intimal hyperplasia induced by balloon injury in rabbits

Journal of lipid research, 2001-04, Vol.42 (4), p.480-488

2001

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Synthesis and Evaluation of a Novel Indoledione Class of Long Chain Fatty Acid Elongase 6 (ELOVL6) Inhibitors

Journal of medicinal chemistry, 2009-05, Vol.52 (10), p.3142-3145

2009

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Discovery and characterization of a novel potent, selective and orally active inhibitor for mammalian ELOVL6

European journal of pharmacology, 2010-03, Vol.630 (1), p.34-41

2010

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Anti-counterfeit Activities of Pharmaceutical Companies in Japan: For Patient Safety

YAKUGAKU ZASSHI, 2014/02/01, Vol.134(2), pp.203-211

2014

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Synthesis and Biological Evaluation of a Novel 3-Sulfonyl-8-azabicyclo[3.2.1]octane Class of Long Chain Fatty Acid Elongase 6 (ELOVL6) Inhibitors

Journal of medicinal chemistry, 2009-07, Vol.52 (14), p.4111-4114

2009

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Discovery of Novel Benzoxazinones as Potent and Orally Active Long Chain Fatty Acid Elongase 6 Inhibitors

Journal of medicinal chemistry, 2009-11, Vol.52 (22), p.7289-7300

2009

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5,5-Dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1 H -pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1 H -indole-2,4-dione, a Potent Inhibitor for Mammalian Elongase of Long-Chain Fatty Acids Family 6: Examination of Its Potential Utility as a Pharmacological Tool

The Journal of pharmacology and experimental therapeutics, 2009-07, Vol.330 (1), p.249-256

2009

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製薬企業における偽造医薬品対策

YAKUGAKU ZASSHI, 2014/02/01, Vol.134(2), pp.203-211

2014

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Hepatic De Novo Lipogenesis Is Present in Liver-Specific ACC1-Deficient Mice

Molecular and cellular biology, 2007-05, Vol.27 (9), p.3556-3556

2007

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Enhanced expression of hepatic acyl‐coenzyme A synthetase and microsomal triglyceride transfer protein messenger RNAs in the obese and hypertriglyceridemic rat with visceral fat accumulation

Hepatology (Baltimore, Md.), 1998-02, Vol.27 (2), p.557-562

1998

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Postprandial Hyperlipidemia in Zucker Diabetic Fatty fa / fa Rats, an Animal Model of Type II Diabetes, and Its Amelioration by Acyl-CoA:Cholesterol Acyltransferase Inhibition

The Japanese Journal of Pharmacology, 2001, Vol.86(1), pp.127-129

2001

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Effect of F-1394, a potent and selective inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), on esterification of cholesterol and basolateral secretion of cholesteryl ester in Caco-2 cells

Folia Pharmacologica Japonica, 1997, Vol.110(6), pp.357-365

1997

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Effects of F-1394, an Acyl-CoA:Cholesterol Acyltransferase (ACAT) Inhibitor, on ACAT Activity in HepG2 Cells and on Hepatic Secretion of Lipids in Triton WR-1339-Induced Hyperlipidemic Rats: Possible Role of Hepatic ACAT in Very Low Density Lipoprotein Secretion

The Japanese Journal of Pharmacology, 1998, Vol.76(3), pp.309-312

1998

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Studies on Acyl-CoA:Cholesterol Acyltransferase (ACAT) Inhibitory Effects and Enzyme Selectivity of F-1394, a Pantotheic Acid Derivative

The Japanese Journal of Pharmacology, 1995, Vol.67(3), pp.195-203

1995

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Hypocholesterolemic Action and Prevention of Cholesterol Absorption via the Gut by F-1394, a Potent Acyl-CoA:Cholesterol Acyltransferase (ACAT) Inhibitor, in Cholesterol Diet-Fed Rats

The Japanese Journal of Pharmacology, 1995, Vol.69(1), pp.53-60

1995

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Hypolipidemic Action of F-1394, an Acyl-CoA : Cholesterol Acyltransferase (ACAT) Inhibitor, in High-Fat Diet Fed Beagle Dogs

YAKUGAKU ZASSHI, 1997/04/25, Vol.117(4), pp.233-241

1997

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高脂肪食負荷ビーグル犬の血清脂質に対するACAT阻害薬, F-1394の作用

YAKUGAKU ZASSHI, 1997/04/25, Vol.117(4), pp.233-241

1997

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Hepatic De Novo Lipogenesis Is Present in Liver-Specific ACC1-Deficient Mice

Acyl-CoA:cholesterol acyltransferase inhibition reduces atherosclerosis in apolipoprotein E-deficient mice

5,5-Dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione, a potent inhibitor for mammalian elongase of long-chain fatty acids family 6: examination of its potential utility as a pharmacological tool

Synthesis and evaluation of a novel 2-azabicyclo[2.2.2]octane class of long chain fatty acid elongase 6 (ELOVL6) inhibitors

Postprandial hyperlipidemia in streptozotocin-induced diabetic rats is due to abnormal increase in intestinal acyl coenzyme A:cholesterol acyltransferase activity

Direct effect of an acyl‐CoA:cholesterol acyltransferase inhibitor, F‐1394, on atherosclerosis in apolipoprotein E and low density lipoprotein receptor double knockout mice

Effect of F-1394, an acyl-CoA:cholesterol acyltransferase inhibitor, on atherosclerosis induced by high cholesterol diet in rabbits

Role of MGAT2 and DGAT1 in the release of gut peptides after triglyceride ingestion

ACAT inhibitor F-1394 prevents intimal hyperplasia induced by balloon injury in rabbits

Synthesis and Evaluation of a Novel Indoledione Class of Long Chain Fatty Acid Elongase 6 (ELOVL6) Inhibitors

Discovery and characterization of a novel potent, selective and orally active inhibitor for mammalian ELOVL6

Anti-counterfeit Activities of Pharmaceutical Companies in Japan: For Patient Safety

Synthesis and Biological Evaluation of a Novel 3-Sulfonyl-8-azabicyclo[3.2.1]octane Class of Long Chain Fatty Acid Elongase 6 (ELOVL6) Inhibitors

Discovery of Novel Benzoxazinones as Potent and Orally Active Long Chain Fatty Acid Elongase 6 Inhibitors

5,5-Dimethyl-3-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1 H -pyrazol-4-yl)-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1 H -indole-2,4-dione, a Potent Inhibitor for Mammalian Elongase of Long-Chain Fatty Acids Family 6: Examination of Its Potential Utility as a Pharmacological Tool

製薬企業における偽造医薬品対策

Hepatic De Novo Lipogenesis Is Present in Liver-Specific ACC1-Deficient Mice

Enhanced expression of hepatic acyl‐coenzyme A synthetase and microsomal triglyceride transfer protein messenger RNAs in the obese and hypertriglyceridemic rat with visceral fat accumulation

Postprandial Hyperlipidemia in Zucker Diabetic Fatty fa / fa Rats, an Animal Model of Type II Diabetes, and Its Amelioration by Acyl-CoA:Cholesterol Acyltransferase Inhibition

Effect of F-1394, a potent and selective inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), on esterification of cholesterol and basolateral secretion of cholesteryl ester in Caco-2 cells

Effects of F-1394, an Acyl-CoA:Cholesterol Acyltransferase (ACAT) Inhibitor, on ACAT Activity in HepG2 Cells and on Hepatic Secretion of Lipids in Triton WR-1339-Induced Hyperlipidemic Rats: Possible Role of Hepatic ACAT in Very Low Density Lipoprotein Secretion

Studies on Acyl-CoA:Cholesterol Acyltransferase (ACAT) Inhibitory Effects and Enzyme Selectivity of F-1394, a Pantotheic Acid Derivative

Hypocholesterolemic Action and Prevention of Cholesterol Absorption via the Gut by F-1394, a Potent Acyl-CoA:Cholesterol Acyltransferase (ACAT) Inhibitor, in Cholesterol Diet-Fed Rats

Hypolipidemic Action of F-1394, an Acyl-CoA : Cholesterol Acyltransferase (ACAT) Inhibitor, in High-Fat Diet Fed Beagle Dogs

高脂肪食負荷ビーグル犬の血清脂質に対するACAT阻害薬, F-1394の作用

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