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A randomized, open-label, parallel pilot study investigating metabolic product kinetics of the novel ketone ester, bis-hexanoyl (R)-1,3-butanediol, over one week of ingestion in healthy adults

Frontiers in physiology, 2023-06, Vol.14, p.1196535-1196535

2023

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Tolerability and Safety of a Novel Ketogenic Ester, Bis-Hexanoyl (R)-1,3-Butanediol: A Randomized Controlled Trial in Healthy Adults

Nutrients, 2021-06, Vol.13 (6), p.2066

2021

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Oral leucine administration stimulates protein synthesis in rat skeletal muscle

The Journal of nutrition, 2005-03, Vol.135 (3), p.376-382

2005

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Leucine Stimulates Translation Initiation in Skeletal Muscle of Postabsorptive Rats via a Rapamycin-Sensitive Pathway

The Journal of nutrition, 2000-10, Vol.130 (10), p.2413-2419

2000

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A Novel Personalized Systems Nutrition Program Improves Dietary Patterns, Lifestyle Behaviors and Health-Related Outcomes: Results from the Habit Study

Nutrients, 2021-05, Vol.13 (6), p.1763

2021

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Signaling Pathways Involved in Translational Control of Protein Synthesis in Skeletal Muscle by Leucine

The Journal of nutrition, 2001-03, Vol.131 (3), p.856S-860S

2001

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Bis Hexanoyl (R)-1,3-Butanediol, a Novel Ketogenic Ester, Acutely Increases Circulating r- and s-ß-Hydroxybutyrate Concentrations in Healthy Adults

Journal of the American Nutrition Association, 2023-02, Vol.42 (2), p.169-177

2023

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Dietary long-chain polyunsaturated fatty acids upregulate expression of FADS3 transcripts

Prostaglandins, leukotrienes and essential fatty acids, 2013-01, Vol.88 (1), p.15-19

2013

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ω-3 Polyunsaturated Fatty Acid Status Testing in Humans: A Narrative Review of Commercially Available Options

The Journal of nutrition, 2024-05, Vol.154 (5), p.1487-1504

2024

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4E-BP1 and S6K1: translational integration sites for nutritional and hormonal information in muscle

American journal of physiology: endocrinology and metabolism, 2000-10, Vol.279 (4), p.E715-E729

2000

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Contribution of insulin to the translational control of protein synthesis in skeletal muscle by leucine

American journal of physiology: endocrinology and metabolism, 2002-05, Vol.282 (5), p.E1092-E1101

2002

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Systems biology of personalized nutrition

Nutrition reviews, 2017-08, Vol.75 (8), p.579-599

2017

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Orally Administered Leucine Enhances Protein Synthesis in Skeletal Muscle of Diabetic Rats in the Absence of Increases in 4E-BP1 or S6K1 Phosphorylation

Diabetes (New York, N.Y.), 2002-04, Vol.51 (4), p.928-936

2002

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Perspective: Guiding Principles for the Implementation of Personalized Nutrition Approaches That Benefit Health and Function

Advances in nutrition (Bethesda, Md.), 2020-01, Vol.11 (1), p.25-34

2020

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The mTOR signaling pathway mediates control of ribosomal protein mRNA translation in rat liver

The international journal of biochemistry & cell biology, 2004-11, Vol.36 (11), p.2169-2179

2004

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Differential cerebral cortex transcriptomes of baboon neonates consuming moderate and high docosahexaenoic acid formulas

PloS one, 2007-04, Vol.2 (4), p.e370-e370

2007

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Assessment of biomarkers of protein anabolism in skeletal muscle during the life span of the rat: sarcopenia despite elevated protein synthesis

American journal of physiology: endocrinology and metabolism, 2004-10, Vol.287 (4), p.E772-E780

2004

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A Novel Powder Formulation of the Ketone Ester, Bis Hexanoyl (R)-1,3-Butanediol, Rapidly Increases Circulating ß-Hydroxybutyrate Concentrations in Healthy Adults

Journal of the American Nutrition Association, 2023-10, Vol.42 (7), p.635-642

2023

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Deficiency of dietary EAA preferentially inhibits mRNA translation of ribosomal proteins in liver of meal-fed rats

American journal of physiology: endocrinology and metabolism, 2001-09, Vol.281 (3), p.E430-E439

2001

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Leucine supplementation enhances skeletal muscle recovery in rats following exercise

The Journal of nutrition, 1999-06, Vol.129 (6), p.1102-1106

1999

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The influence of moderate and high dietary long chain polyunsaturated fatty acids (LCPUFA) on baboon neonate tissue fatty acids

Pediatric research, 2007-05, Vol.61 (5 Pt 1), p.537-545

2007

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AMPing Down Leucine Action in Skeletal Muscle

The Journal of nutrition, 2008-12, Vol.138 (12), p.2307-2308

2008

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Oral Administration of Leucine Stimulates Ribosomal Protein mRNA Translation but Not Global Rates of Protein Synthesis in the Liver of Rats

The Journal of nutrition, 2001-04, Vol.131 (4), p.1171-1176

2001

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AMPing Down Leucine Action in Skeletal Muscle1

The Journal of nutrition, 2008-12, Vol.138 (12), p.2307-2308

2008

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90-Day oral (gavage) study in rats with galactooligosaccharides syrup

Food and chemical toxicology, 2006-06, Vol.44 (6), p.819-826

2006

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A randomized, open-label, parallel pilot study investigating metabolic product kinetics of the novel ketone ester, bis-hexanoyl (R)-1,3-butanediol, over one week of ingestion in healthy adults

Tolerability and Safety of a Novel Ketogenic Ester, Bis-Hexanoyl (R)-1,3-Butanediol: A Randomized Controlled Trial in Healthy Adults

Oral leucine administration stimulates protein synthesis in rat skeletal muscle

Leucine Stimulates Translation Initiation in Skeletal Muscle of Postabsorptive Rats via a Rapamycin-Sensitive Pathway

A Novel Personalized Systems Nutrition Program Improves Dietary Patterns, Lifestyle Behaviors and Health-Related Outcomes: Results from the Habit Study

Signaling Pathways Involved in Translational Control of Protein Synthesis in Skeletal Muscle by Leucine

Bis Hexanoyl (R)-1,3-Butanediol, a Novel Ketogenic Ester, Acutely Increases Circulating r- and s-ß-Hydroxybutyrate Concentrations in Healthy Adults

Dietary long-chain polyunsaturated fatty acids upregulate expression of FADS3 transcripts

ω-3 Polyunsaturated Fatty Acid Status Testing in Humans: A Narrative Review of Commercially Available Options

4E-BP1 and S6K1: translational integration sites for nutritional and hormonal information in muscle

Contribution of insulin to the translational control of protein synthesis in skeletal muscle by leucine

Systems biology of personalized nutrition

Orally Administered Leucine Enhances Protein Synthesis in Skeletal Muscle of Diabetic Rats in the Absence of Increases in 4E-BP1 or S6K1 Phosphorylation

Perspective: Guiding Principles for the Implementation of Personalized Nutrition Approaches That Benefit Health and Function

The mTOR signaling pathway mediates control of ribosomal protein mRNA translation in rat liver

Differential cerebral cortex transcriptomes of baboon neonates consuming moderate and high docosahexaenoic acid formulas

Assessment of biomarkers of protein anabolism in skeletal muscle during the life span of the rat: sarcopenia despite elevated protein synthesis

A Novel Powder Formulation of the Ketone Ester, Bis Hexanoyl (R)-1,3-Butanediol, Rapidly Increases Circulating ß-Hydroxybutyrate Concentrations in Healthy Adults

Deficiency of dietary EAA preferentially inhibits mRNA translation of ribosomal proteins in liver of meal-fed rats

Leucine supplementation enhances skeletal muscle recovery in rats following exercise

The influence of moderate and high dietary long chain polyunsaturated fatty acids (LCPUFA) on baboon neonate tissue fatty acids

AMPing Down Leucine Action in Skeletal Muscle

Oral Administration of Leucine Stimulates Ribosomal Protein mRNA Translation but Not Global Rates of Protein Synthesis in the Liver of Rats

AMPing Down Leucine Action in Skeletal Muscle1

90-Day oral (gavage) study in rats with galactooligosaccharides syrup

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