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In Vitro and In Vivo Properties of Ro 63-9141, a Novel Broad-Spectrum Cephalosporin with Activity against Methicillin-Resistant Staphylococci

Antimicrobial Agents and Chemotherapy, 2001-03, Vol.45 (3), p.825-836

2001

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Antibacterial activities of epiroprim, a new dihydrofolate reductase inhibitor, alone and in combination with dapsone

Antimicrobial Agents and Chemotherapy, 1996-06, Vol.40 (6), p.1376-1381

1996

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GyrB mutations in Staphylococcus aureus strains resistant to cyclothialidine, coumermycin, and novobiocin

Antimicrobial Agents and Chemotherapy, 1996-04, Vol.40 (4), p.1060-1062

1996

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Pyrimido[1,6-a]benzimidazoles: a new class of DNA gyrase inhibitors

Journal of medicinal chemistry, 1992-04, Vol.35 (8), p.1385-1392

1992

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New Antibacterial Agents Derived from the DNA Gyrase Inhibitor Cyclothialidine

Journal of medicinal chemistry, 2004-03, Vol.47 (6), p.1487-1513

2004

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Trapping of nonhydrolyzable cephalosporins by cephalosporinases in Enterobacter cloacae and Pseudomonas aeruginosa as a possible resistance mechanism

Antimicrobial Agents and Chemotherapy, 1982-05, Vol.21 (5), p.711-717

1982

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Design, synthesis, and structure-activity relationship studies of ATP analogues as DNA gyrase inhibitors

Bioorganic & medicinal chemistry letters, 2000-04, Vol.10 (8), p.821-826

2000

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Cyclothialidine and its congeners: A new class of DNA gyrase inhibitors

Pharmacology & therapeutics (Oxford), 1993-01, Vol.60 (2), p.367-380

1993

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Antibacterial properties of Ro 40-6890, a broad-spectrum cephalosporin, and its novel orally absorbable ester, Ro 41-3399

Antimicrobial Agents and Chemotherapy, 1992-12, Vol.36 (12), p.2825-2834

1992

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Novel ketolide antibiotics with a fused five-membered lactone ring––synthesis, physicochemical and antimicrobial properties

Bioorganic & medicinal chemistry, 2004-07, Vol.12 (13), p.3503-3519

2004

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(6R)-6-(SUBSTITUTED METHYL)PENICILLANIC ACID SULFONES: NEW POTENT β-LACTAMASE INHIBITORS

The Journal of Antibiotics, 1993/04/25, Vol.46(4), pp.641-646

1993

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Antibacterial properties of carumonam (Ro 17-2301, AMA-1080), a new sulfonated monocyclic beta-lactam antibiotic

Chemotherapy (Basel), 1985-01, Vol.31 (6), p.440-450

Angehrn, P

1985

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In vitro and in vivo evaluation of Ro 09-1428, a new parenteral cephalosporin with high antipseudomonal activity

Antimicrobial Agents and Chemotherapy, 1991-04, Vol.35 (4), p.653-659

1991

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Multiply resistant mutants of Enterobacter cloacae selected by beta-lactam antibiotics

Antimicrobial Agents and Chemotherapy, 1986-11, Vol.30 (5), p.684-688

1986

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Ro 13-9904, a long-acting broad-spectrum cephalosporin: in vitro and in vivo studies

Antimicrobial Agents and Chemotherapy, 1980-12, Vol.18 (6), p.913-921

1980

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In vitro and in vivo synergy between ceftriaxone and aminoglycosides against Pseudomonas aeruginosa

European journal of clinical microbiology, 1983-10, Vol.2 (5), p.489

Angehrn, P

1983

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Methylene (2S,5R)-6-(3-formylallylidene)penicillanate pivalate, a prodrug of a new β-lactamase inhibitor

Journal of antibiotics, 1992, Vol.45 (4), p.587-588

1992

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In vitro antibacterial properties of cefetamet and in vivo activity of its orally absorbable ester derivative, cefetamet pivoxil

European journal of clinical microbiology & infectious diseases, 1989-06, Vol.8 (6), p.536-543

1989

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Structure-Based Design of β-Lactamase Inhibitors. 1. Synthesis and Evaluation of Bridged Monobactams

Journal of medicinal chemistry, 1998-10, Vol.41 (21), p.3961-3971

1998

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METHYLENE (2S, 5R)-6-(3-FORMYLALLYLIDENE)PENICILLANATE PIVALATE, A PRODRUG OF A NEW β-LACTAMASE INHIBITOR

The Journal of Antibiotics, 1992/04/25, Vol.45(4), pp.587-588

1992

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Monocyclic and tricyclic analogs of quinolones: mechanism of action

Antimicrobial Agents and Chemotherapy, 1987-04, Vol.31 (4), p.614-616

1987

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Design, Synthesis, and Evaluation of 2β-Alkenyl Penam Sulfone Acids as Inhibitors of β-Lactamases

Journal of medicinal chemistry, 1996-09, Vol.39 (19), p.3712-3722

1996

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POTENTIAL PRODRUGS OF 6-ACETYLMETHYLENEPENICILLANIC ACID (Ro 15-1903)

The Journal of Antibiotics, 1986, Vol.39(6), pp.833-838

1986

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Ro 13-9904/001, A NOVEL POTENT AND LONG-ACTING PARENTERAL CEPHALOSPORIN

The Journal of Antibiotics, 1980, Vol.33(7), pp.783-786

1980

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Low Trimethoprim Susceptibility of Anaerobic Bacteria Due to Insensitive Dihydrofolate Reductases

Antimicrobial Agents and Chemotherapy, 1979-01, Vol.15 (1), p.1-6

1979

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In Vitro and In Vivo Properties of Ro 63-9141, a Novel Broad-Spectrum Cephalosporin with Activity against Methicillin-Resistant Staphylococci

Antibacterial activities of epiroprim, a new dihydrofolate reductase inhibitor, alone and in combination with dapsone

GyrB mutations in Staphylococcus aureus strains resistant to cyclothialidine, coumermycin, and novobiocin

Pyrimido[1,6-a]benzimidazoles: a new class of DNA gyrase inhibitors

New Antibacterial Agents Derived from the DNA Gyrase Inhibitor Cyclothialidine

Trapping of nonhydrolyzable cephalosporins by cephalosporinases in Enterobacter cloacae and Pseudomonas aeruginosa as a possible resistance mechanism

Design, synthesis, and structure-activity relationship studies of ATP analogues as DNA gyrase inhibitors

Cyclothialidine and its congeners: A new class of DNA gyrase inhibitors

Antibacterial properties of Ro 40-6890, a broad-spectrum cephalosporin, and its novel orally absorbable ester, Ro 41-3399

Novel ketolide antibiotics with a fused five-membered lactone ring––synthesis, physicochemical and antimicrobial properties

(6R)-6-(SUBSTITUTED METHYL)PENICILLANIC ACID SULFONES: NEW POTENT β-LACTAMASE INHIBITORS

Antibacterial properties of carumonam (Ro 17-2301, AMA-1080), a new sulfonated monocyclic beta-lactam antibiotic

In vitro and in vivo evaluation of Ro 09-1428, a new parenteral cephalosporin with high antipseudomonal activity

Multiply resistant mutants of Enterobacter cloacae selected by beta-lactam antibiotics

Ro 13-9904, a long-acting broad-spectrum cephalosporin: in vitro and in vivo studies

In vitro and in vivo synergy between ceftriaxone and aminoglycosides against Pseudomonas aeruginosa

Methylene (2S,5R)-6-(3-formylallylidene)penicillanate pivalate, a prodrug of a new β-lactamase inhibitor

In vitro antibacterial properties of cefetamet and in vivo activity of its orally absorbable ester derivative, cefetamet pivoxil

Structure-Based Design of β-Lactamase Inhibitors. 1. Synthesis and Evaluation of Bridged Monobactams

METHYLENE (2S, 5R)-6-(3-FORMYLALLYLIDENE)PENICILLANATE PIVALATE, A PRODRUG OF A NEW β-LACTAMASE INHIBITOR

Monocyclic and tricyclic analogs of quinolones: mechanism of action

Design, Synthesis, and Evaluation of 2β-Alkenyl Penam Sulfone Acids as Inhibitors of β-Lactamases

POTENTIAL PRODRUGS OF 6-ACETYLMETHYLENEPENICILLANIC ACID (Ro 15-1903)

Ro 13-9904/001, A NOVEL POTENT AND LONG-ACTING PARENTERAL CEPHALOSPORIN

Low Trimethoprim Susceptibility of Anaerobic Bacteria Due to Insensitive Dihydrofolate Reductases

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