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Probe for the measurement of cell surface pH in vivo and ex vivo

Proceedings of the National Academy of Sciences - PNAS, 2016-07, Vol.113 (29), p.8177-8181

2016

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Peptides of pHLIP family for targeted intracellular and extracellular delivery of cargo molecules to tumors

Proceedings of the National Academy of Sciences - PNAS, 2018-03, Vol.115 (12), p.E2811-E2818

2018

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T-cells produce acidic niches in lymph nodes to suppress their own effector functions

Nature communications, 2020-08, Vol.11 (1), p.4113-13, Article 4113

2020

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Applications of pHLIP Technology for Cancer Imaging and Therapy

Trends in biotechnology (Regular ed.), 2017-07, Vol.35 (7), p.653-664

2017

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Family of pH (low) insertion peptides for tumor targeting

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (15), p.5834-5839

2013

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Targeted imaging of urothelium carcinoma in human bladders by an ICG pHLIP peptide ex vivo

Proceedings of the National Academy of Sciences - PNAS, 2016-10, Vol.113 (42), p.11829-11834

2016

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pHLIP peptide targets nanogold particles to tumors

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (2), p.465-470

2013

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Aiming the magic bullet: targeted delivery of imaging and therapeutic agents to solid tumors by pHLIP peptides

Frontiers in pharmacology, 2024-03, Vol.15, p.1355893-1355893

2024

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pH-(low)-insertion-peptide (pHLIP) translocation of membrane impermeable phalloidin toxin inhibits cancer cell proliferation

Proceedings of the National Academy of Sciences - PNAS, 2010-11, Vol.107 (47), p.20246-20250

2010

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Enhancement of radiation effect on cancer cells by gold-pHLIP

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (17), p.5372-5376

2015

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pH (low) insertion peptide (pHLIP) inserts across a lipid bilayer as a helix and exits by a different path

Proceedings of the National Academy of Sciences - PNAS, 2010-03, Vol.107 (9), p.4081-4086

2010

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Targeting diseased tissues by pHLIP insertion at low cell surface pH

Frontiers in physiology, 2014-03, Vol.5, p.97

2014

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pHLIP ICG for delineation of tumors and blood flow during fluorescence-guided surgery

Scientific reports, 2020-10, Vol.10 (1), p.18356, Article 18356

2020

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Energetics of peptide (pHLIP) binding to and folding across a lipid bilayer membrane

Proceedings of the National Academy of Sciences - PNAS, 2008-10, Vol.105 (40), p.15340-15345

2008

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Eradication of tumors and development of anti-cancer immunity using STINGa targeted by pHLIP

Frontiers in oncology, 2022-10, Vol.12, p.1023959-1023959

2022

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Ex-vivo Imaging of Upper Tract Urothelial Carcinoma Using Novel pH Low Insertion Peptide (Variant 3), a Molecular Imaging Probe

Urology (Ridgewood, N.J.), 2020-05, Vol.139, p.134-140

2020

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The pH low insertion peptide pHLIP Variant 3 as a novel marker of acidic malignant lesions

Proceedings of the National Academy of Sciences - PNAS, 2015-08, Vol.112 (31), p.9710-9715

2015

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Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo

Proceedings of the National Academy of Sciences - PNAS, 2007-05, Vol.104 (19), p.7893-7898

2007

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Targeting pancreatic ductal adenocarcinoma acidic microenvironment

Scientific reports, 2014-03, Vol.4 (1), p.4410-4410, Article 4410

2014

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pH (low) insertion peptide (pHLIP) targets ischemic myocardium

Proceedings of the National Academy of Sciences - PNAS, 2013-01, Vol.110 (1), p.82-86

2013

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Targeted intracellular delivery of dimeric STINGa by two pHLIP peptides for treatment of solid tumors

Frontiers in pharmacology, 2024-03, Vol.15, p.1346756-1346756

2024

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Modulation of the pHLIP Transmembrane Helix Insertion Pathway

Biophysical journal, 2012-04, Vol.102 (8), p.1846-1855

2012

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Targeting Acidic Diseased Tissues by pH-Triggered Membrane-Associated Peptide Folding

Frontiers in bioengineering and biotechnology, 2020-04, Vol.8, p.335-335

2020

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Targeting acidic pre-metastatic niche in lungs by pH low insertion peptide and its utility for anti-metastatic therapy

Frontiers in oncology, 2023-11, Vol.13, p.1258442-1258442

2023

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Translocation of Molecules into Cells by pH-Dependent Insertion of a Transmembrane Helix

Proceedings of the National Academy of Sciences - PNAS, 2006-04, Vol.103 (17), p.6460-6465

2006

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Probe for the measurement of cell surface pH in vivo and ex vivo

Peptides of pHLIP family for targeted intracellular and extracellular delivery of cargo molecules to tumors

T-cells produce acidic niches in lymph nodes to suppress their own effector functions

Applications of pHLIP Technology for Cancer Imaging and Therapy

Family of pH (low) insertion peptides for tumor targeting

Targeted imaging of urothelium carcinoma in human bladders by an ICG pHLIP peptide ex vivo

pHLIP peptide targets nanogold particles to tumors

Aiming the magic bullet: targeted delivery of imaging and therapeutic agents to solid tumors by pHLIP peptides

pH-(low)-insertion-peptide (pHLIP) translocation of membrane impermeable phalloidin toxin inhibits cancer cell proliferation

Enhancement of radiation effect on cancer cells by gold-pHLIP

pH (low) insertion peptide (pHLIP) inserts across a lipid bilayer as a helix and exits by a different path

Targeting diseased tissues by pHLIP insertion at low cell surface pH

pHLIP ICG for delineation of tumors and blood flow during fluorescence-guided surgery

Energetics of peptide (pHLIP) binding to and folding across a lipid bilayer membrane

Eradication of tumors and development of anti-cancer immunity using STINGa targeted by pHLIP

Ex-vivo Imaging of Upper Tract Urothelial Carcinoma Using Novel pH Low Insertion Peptide (Variant 3), a Molecular Imaging Probe

The pH low insertion peptide pHLIP Variant 3 as a novel marker of acidic malignant lesions

Mechanism and uses of a membrane peptide that targets tumors and other acidic tissues in vivo

Targeting pancreatic ductal adenocarcinoma acidic microenvironment

pH (low) insertion peptide (pHLIP) targets ischemic myocardium

Targeted intracellular delivery of dimeric STINGa by two pHLIP peptides for treatment of solid tumors

Modulation of the pHLIP Transmembrane Helix Insertion Pathway

Targeting Acidic Diseased Tissues by pH-Triggered Membrane-Associated Peptide Folding

Targeting acidic pre-metastatic niche in lungs by pH low insertion peptide and its utility for anti-metastatic therapy

Translocation of Molecules into Cells by pH-Dependent Insertion of a Transmembrane Helix

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