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Crizotinib, a c-Met inhibitor, prevents metastasis in a metastatic uveal melanoma model

Molecular cancer therapeutics, 2013-12, Vol.12 (12), p.2817-2826

2013

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BRD4-targeted therapy induces Myc-independent cytotoxicity in Gnaq/11-mutatant uveal melanoma cells

Oncotarget, 2015-10, Vol.6 (32), p.33397-33409

2015

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Stromal fibroblast growth factor 2 reduces the efficacy of bromodomain inhibitors in uveal melanoma

EMBO molecular medicine, 2019-02, Vol.11 (2), p.1-n/a

2019

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Identification of Unique MEK-Dependent Genes in GNAQ Mutant Uveal Melanoma Involved in Cell Growth, Tumor Cell Invasion, and MEK Resistance

Clinical cancer research, 2012-07, Vol.18 (13), p.3552-3561

2012

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Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma

Cancer research (Chicago, Ill.), 2007-07, Vol.67 (14), p.6626-6636

2007

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Overexpression of DDX43 mediates MEK inhibitor resistance through RAS Upregulation in uveal melanoma cells

Molecular cancer therapeutics, 2014-08, Vol.13 (8), p.2073-2080

2014

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Impact of combined mTOR and MEK inhibition in uveal melanoma is driven by tumor genotype

PloS one, 2012-07, Vol.7 (7), p.e40439

2012

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Intermittent MEK inhibition for the treatment of metastatic uveal melanoma

Frontiers in oncology, 2022-09, Vol.12, p.975643

2022

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Adjuvant crizotinib in high-risk uveal melanoma following definitive therapy

Frontiers in oncology, 2022-08, Vol.12, p.976837-976837

2022

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Control of apoptosis and mitotic spindle checkpoint by survivin

Nature (London), 1998-12, Vol.396 (6711), p.580-584

1998

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Aurora B kinase regulates the postmitotic endoreduplication checkpoint via phosphorylation of the retinoblastoma protein at serine 780

Molecular biology of the cell, 2009-04, Vol.20 (8), p.2218-2228

2009

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Safingol (l-threo-sphinganine) induces autophagy in solid tumor cells through inhibition of PKC and the PI3-kinase pathway

Autophagy, 2009-02, Vol.5 (2), p.184-193

2009

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Abstract B29: Differential effects of BRD4 inhibition on uveal melanoma cells with Gnaq/11 mutations

Cancer research (Chicago, Ill.), 2015-07, Vol.75 (14_Supplement), p.B29-B29

Ambrosini, Grazia

2015

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Sorafenib inhibits growth and mitogen-activated protein kinase signaling in malignant peripheral nerve sheath cells

Molecular cancer therapeutics, 2008-04, Vol.7 (4), p.890-896

2008

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Abstract 1115: BET bromodomain inhibition synergizes with MEK inhibitors in uveal melanoma

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1115-1115

2021

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Flavopiridol targets c-KIT transcription and induces apoptosis in gastrointestinal stromal tumor cells

Cancer research (Chicago, Ill.), 2006-06, Vol.66 (11), p.5858-5866

2006

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Abstract 4462: Cytotoxic effects of a novel BRD4 inhibitor in uveal melanoma cells with Gnaq11 mutations

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4462-4462

2016

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Abstract 4462: Cytotoxic effects of a novel BRD4 inhibitor in uveal melanoma cells with Gnaq/11 mutations

Cancer research (Chicago, Ill.), 2016-07, Vol.76 (14_Supplement), p.4462-4462

2016

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Abstract 6082: Uveal melanoma exosomes express MET and re-program the recipient cells

Cancer research (Chicago, Ill.), 2020-08, Vol.80 (16_Supplement), p.6082-6082

2020

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Uveal Melanoma Exosomes Induce a Prometastatic Microenvironment through Macrophage Migration Inhibitory Factor

Molecular cancer research, 2022-04, Vol.20 (4), p.661-669

2022

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Abstract 291: Sequential treatment with the Wee1 inhibitor, AZD1775, enhances the effect of trabectedin in the L-sarcomas

Cancer research (Chicago, Ill.), 2017-07, Vol.77 (13_Supplement), p.291-291

2017

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Abstract 1410: Gnaq/11 mutant uveal melanoma is susceptible to Brd4 inhibition by JQ1

Cancer research (Chicago, Ill.), 2014-10, Vol.74 (19_Supplement), p.1410-1410

2014

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Abstract 5784: A novel ERK inhibitor in the treatment of uveal melanoma

Cancer research (Chicago, Ill.), 2018-07, Vol.78 (13_Supplement), p.5784-5784

2018

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Inhibition of mutant GNAQ signaling in uveal melanoma induces AMPK-dependent autophagic cell death

Molecular cancer therapeutics, 2013-05, Vol.12 (5), p.768-776

2013

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The phosphoinositide 3-kinase α selective inhibitor BYL719 enhances the effect of the protein kinase C inhibitor AEB071 in GNAQ/GNA11-mutant uveal melanoma cells

Molecular cancer therapeutics, 2014-05, Vol.13 (5), p.1044-1053

2014

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Crizotinib, a c-Met inhibitor, prevents metastasis in a metastatic uveal melanoma model

BRD4-targeted therapy induces Myc-independent cytotoxicity in Gnaq/11-mutatant uveal melanoma cells

Stromal fibroblast growth factor 2 reduces the efficacy of bromodomain inhibitors in uveal melanoma

Identification of Unique MEK-Dependent Genes in GNAQ Mutant Uveal Melanoma Involved in Cell Growth, Tumor Cell Invasion, and MEK Resistance

Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma

Overexpression of DDX43 mediates MEK inhibitor resistance through RAS Upregulation in uveal melanoma cells

Impact of combined mTOR and MEK inhibition in uveal melanoma is driven by tumor genotype

Intermittent MEK inhibition for the treatment of metastatic uveal melanoma

Adjuvant crizotinib in high-risk uveal melanoma following definitive therapy

Control of apoptosis and mitotic spindle checkpoint by survivin

Aurora B kinase regulates the postmitotic endoreduplication checkpoint via phosphorylation of the retinoblastoma protein at serine 780

Safingol (l-threo-sphinganine) induces autophagy in solid tumor cells through inhibition of PKC and the PI3-kinase pathway

Abstract B29: Differential effects of BRD4 inhibition on uveal melanoma cells with Gnaq/11 mutations

Sorafenib inhibits growth and mitogen-activated protein kinase signaling in malignant peripheral nerve sheath cells

Abstract 1115: BET bromodomain inhibition synergizes with MEK inhibitors in uveal melanoma

Flavopiridol targets c-KIT transcription and induces apoptosis in gastrointestinal stromal tumor cells

Abstract 4462: Cytotoxic effects of a novel BRD4 inhibitor in uveal melanoma cells with Gnaq11 mutations

Abstract 4462: Cytotoxic effects of a novel BRD4 inhibitor in uveal melanoma cells with Gnaq/11 mutations

Abstract 6082: Uveal melanoma exosomes express MET and re-program the recipient cells

Uveal Melanoma Exosomes Induce a Prometastatic Microenvironment through Macrophage Migration Inhibitory Factor

Abstract 291: Sequential treatment with the Wee1 inhibitor, AZD1775, enhances the effect of trabectedin in the L-sarcomas

Abstract 1410: Gnaq/11 mutant uveal melanoma is susceptible to Brd4 inhibition by JQ1

Abstract 5784: A novel ERK inhibitor in the treatment of uveal melanoma

Inhibition of mutant GNAQ signaling in uveal melanoma induces AMPK-dependent autophagic cell death

The phosphoinositide 3-kinase α selective inhibitor BYL719 enhances the effect of the protein kinase C inhibitor AEB071 in GNAQ/GNA11-mutant uveal melanoma cells

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