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Triterpene and diterpene inhibitors of pyruvate dehydrogenase kinase (PDK)

Bioorganic & medicinal chemistry letters, 1999-08, Vol.9 (15), p.2223-2228

1999

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Perhydroquinolylbenzamides as Novel Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1

Journal of medicinal chemistry, 2005-10, Vol.48 (21), p.6696-6712

2005

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Hypoglycemic Prodrugs of 4-(2,2-Dimethyl-1-oxopropyl)benzoic Acid

Journal of medicinal chemistry, 1999-01, Vol.42 (1), p.153-163

1999

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Total synthesis of halichondrin B and norhalichondrin B

Journal of the American Chemical Society, 1992-04, Vol.114 (8), p.3162-3164

1992

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Substituted Tetrahydropyrrolo[2,1-b]oxazol-5(6H)-ones and Tetrahydropyrrolo[2,1-b]thiazol-5(6H)-ones as Hypoglycemic Agents

Journal of medicinal chemistry, 1998-11, Vol.41 (23), p.4556-4566

1998

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Heterologously expressed inner lipoyl domain of dihydrolipoyl acetyltransferase inhibits ATP-dependent inactivation of pyruvate dehydrogenase complex. Identification of important amino acid residues

Biochemical journal, 1998-09, Vol.334 ( Pt 3) (Pt 3), p.703-711

1998

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Synthetic studies towards halichondrins

Tetrahedron letters, 1987, Vol.28 (30), p.3463-3466

1987

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Synthetic Studies towards Halichondrins: Synthesis of the C.27–C.38 Segment

Tetrahedron letters, 1992-03, Vol.33 (12), p.1549-1552

1992

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Diverse mechanisms of inhibition of pyruvate dehydrogenase kinase by structurally distinct inhibitors

Biochimica et biophysica acta, 2000-07, Vol.1480 (1), p.283-292

2000

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Secondary Amides of (R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionic Acid as Inhibitors of Pyruvate Dehydrogenase Kinase

Journal of medicinal chemistry, 2000-01, Vol.43 (2), p.236-249

2000

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Anilides of (R)-Trifluoro-2-hydroxy-2-methylpropionic Acid as Inhibitors of Pyruvate Dehydrogenase Kinase

Journal of medicinal chemistry, 2000-06, Vol.43 (11), p.2248-2257

2000

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( R )-3,3,3-Trifluoro-2-hydroxy-2-methylpropionamides Are Orally Active Inhibitors of Pyruvate Dehydrogenase Kinase

Journal of medicinal chemistry, 1999-07, Vol.42 (15), p.2741-2746

1999

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(R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionamides Are Orally Active Inhibitors of Pyruvate Dehydrogenase Kinase

Journal of medicinal chemistry, 1999-07, Vol.42 (15), p.2741-2746

1999

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Synthesis of chiral tetrahydropyrrolo[2,1-b]thiazol-5(6H)-ones

Tetrahedron letters, 1998-11, Vol.39 (47), p.8579-8580

1998

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(R)-3,3,3-trifluoro-2-hydroxy-2-methyl-propionamides are orally active inhibitors of pyruvate dehydrogenase kinase

Journal of medicinal chemistry, 1999, Vol.42 (15), p.2741-2746

1999

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Substituted tetrahydropyrrolo[2,1-b]oxazol-5(6H)-ones and tetrahydropyrrolo[2,1-b]thiazol-5(6H)-one as hypoglycemic agents

Journal of medicinal chemistry, 1998, Vol.41 (23), p.4556-4566

1998

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ChemInform Abstract: Synthesis of Chiral Tetrahydropyrrolo[2,1-b]thiazol-5(6H)-ones

ChemInform, 1999-02, Vol.30 (6), p.no-no

1999

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ChemInform Abstract: Total Synthesis of Halichondrin B and Norhalichondrin B

ChemInform, 1992-08, Vol.23 (32), p.no-no

1992

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Distribution of CB1 cannabinoid receptors and their relationship with mu-opioid receptors in the rat periaqueductal gray

Neuroscience, 2012-06, Vol.213, p.191-200

2012

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Suture Annuloplasty Significantly Improves the Durability of Bicuspid Aortic Valve Repair

The Annals of thoracic surgery, 2017-02, Vol.103 (2), p.504-510

2017

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Neurobiological research on N,N-dimethyltryptamine (DMT) and its potentiation by monoamine oxidase (MAO) inhibition: from ayahuasca to synthetic combinations of DMT and MAO inhibitors

Cellular and molecular life sciences : CMLS, 2024-12, Vol.81 (1), p.395, Article 395

2024

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Human Mesenchymal Stromal Cells from Different Sources Diverge in Their Expression of Cell Surface Proteins and Display Distinct Differentiation Patterns

Stem cells international, 2016-01, Vol.2016 (2016), p.1-9

2016

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Modeling host genetic regulation of influenza pathogenesis in the collaborative cross

PLoS pathogens, 2013-02, Vol.9 (2), p.e1003196-e1003196

2013

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Corneal afferents differentially target thalamic- and parabrachial-projecting neurons in spinal trigeminal nucleus caudalis

Neuroscience, 2013-03, Vol.232, p.182-193

2013

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Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers

BMC genomics, 2009-08, Vol.10 (1), p.373-373, Article 373

2009

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Triterpene and diterpene inhibitors of pyruvate dehydrogenase kinase (PDK)

Perhydroquinolylbenzamides as Novel Inhibitors of 11β-Hydroxysteroid Dehydrogenase Type 1

Hypoglycemic Prodrugs of 4-(2,2-Dimethyl-1-oxopropyl)benzoic Acid

Total synthesis of halichondrin B and norhalichondrin B

Substituted Tetrahydropyrrolo[2,1-b]oxazol-5(6H)-ones and Tetrahydropyrrolo[2,1-b]thiazol-5(6H)-ones as Hypoglycemic Agents

Heterologously expressed inner lipoyl domain of dihydrolipoyl acetyltransferase inhibits ATP-dependent inactivation of pyruvate dehydrogenase complex. Identification of important amino acid residues

Synthetic studies towards halichondrins

Synthetic Studies towards Halichondrins: Synthesis of the C.27–C.38 Segment

Diverse mechanisms of inhibition of pyruvate dehydrogenase kinase by structurally distinct inhibitors

Secondary Amides of (R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionic Acid as Inhibitors of Pyruvate Dehydrogenase Kinase

Anilides of (R)-Trifluoro-2-hydroxy-2-methylpropionic Acid as Inhibitors of Pyruvate Dehydrogenase Kinase

( R )-3,3,3-Trifluoro-2-hydroxy-2-methylpropionamides Are Orally Active Inhibitors of Pyruvate Dehydrogenase Kinase

(R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionamides Are Orally Active Inhibitors of Pyruvate Dehydrogenase Kinase

Synthesis of chiral tetrahydropyrrolo[2,1-b]thiazol-5(6H)-ones

(R)-3,3,3-trifluoro-2-hydroxy-2-methyl-propionamides are orally active inhibitors of pyruvate dehydrogenase kinase

Substituted tetrahydropyrrolo[2,1-b]oxazol-5(6H)-ones and tetrahydropyrrolo[2,1-b]thiazol-5(6H)-one as hypoglycemic agents

ChemInform Abstract: Synthesis of Chiral Tetrahydropyrrolo[2,1-b]thiazol-5(6H)-ones

ChemInform Abstract: Total Synthesis of Halichondrin B and Norhalichondrin B

Distribution of CB1 cannabinoid receptors and their relationship with mu-opioid receptors in the rat periaqueductal gray

Suture Annuloplasty Significantly Improves the Durability of Bicuspid Aortic Valve Repair

Neurobiological research on N,N-dimethyltryptamine (DMT) and its potentiation by monoamine oxidase (MAO) inhibition: from ayahuasca to synthetic combinations of DMT and MAO inhibitors

Human Mesenchymal Stromal Cells from Different Sources Diverge in Their Expression of Cell Surface Proteins and Display Distinct Differentiation Patterns

Modeling host genetic regulation of influenza pathogenesis in the collaborative cross

Corneal afferents differentially target thalamic- and parabrachial-projecting neurons in spinal trigeminal nucleus caudalis

Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers

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