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Islet G protein-coupled receptors as potential targets for treatment of type 2 diabetes

Nature reviews. Drug discovery, 2009-05, Vol.8 (5), p.369-385

Ahrén, Bo

2009

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Paradigm Shift in the Management of Metabolic Diseases—Next-Generation Incretin Therapy

Endocrinology (Philadelphia), 2023-11, Vol.164 (12)

Ahrén, Bo

2023

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Glucagon – Early breakthroughs and recent discoveries

Peptides (New York, N.Y. : 1980), 2015-05, Vol.67, p.74-81

Ahrén, Bo

2015

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DPP-4 Inhibition and the Path to Clinical Proof

Frontiers in endocrinology (Lausanne), 2019-06, Vol.10 (JUN), p.376-376

Ahrén, Bo

2019

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Glucagon-like peptide-1 and beta cell glucose sensitivity - a glucose ramp study in mice

Peptides (New York, N.Y. : 1980), 2021-12, Vol.146, p.170650-170650, Article 170650

Ahrén, Bo

2021

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GLP-1 for type 2 diabetes

Experimental cell research, 2011-05, Vol.317 (9), p.1239-1245

Ahrén, Bo

2011

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Dipeptidyl peptidase-4 inhibitors: Clinical data and clinical implications

Diabetes care, 2007-06, Vol.30 (6), p.1344-1350

AHREN, Bo

2007

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Pleiotropic Mechanisms for the Glucose-Lowering Action of DPP-4 Inhibitors

Diabetes (New York, N.Y.), 2014-07, Vol.63 (7), p.2196-2202

2014

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Gut hormone-based pharmacology: novel formulations and future possibilities for metabolic disease therapy

Diabetologia, 2023-10, Vol.66 (10), p.1796-1808

2023

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Glucagon‐like peptide‐1 receptor agonists for type 2 diabetes: A rational drug development

Journal of diabetes investigation, 2019-03, Vol.10 (2), p.196-201

Ahrén, Bo

2019

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Glucose‐dependent insulinotropic polypeptide secretion after oral macronutrient ingestion: The human literature revisited and a systematic study in model experiments in mice

Journal of diabetes investigation, 2022-10, Vol.13 (10), p.1655-1665

Ahrén, Bo

2022

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The dual incretin co-agonist tirzepatide increases both insulin secretion and glucose effectiveness in model experiments in mice

Peptides (New York, N.Y. : 1980), 2024-01, Vol.171, p.171117-171117, Article 171117

2024

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Surrogate measures of insulin sensitivity vs the hyperinsulinaemic–euglycaemic clamp: a meta-analysis

Diabetologia, 2014-09, Vol.57 (9), p.1781-1788

2014

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Glucose‐lowering action through targeting islet dysfunction in type 2 diabetes: Focus on dipeptidyl peptidase‐4 inhibition

Journal of diabetes investigation, 2021-07, Vol.12 (7), p.1128-1135

Ahrén, Bo

2021

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Creative use of novel glucose-lowering drugs for type 2 diabetes: where will we head in the next 50 years?

Diabetologia, 2015-08, Vol.58 (8), p.1740-1744

Ahrén, Bo

2015

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Glucose effectiveness: Lessons from studies on insulin‐independent glucose clearance in mice

Journal of diabetes investigation, 2021-05, Vol.12 (5), p.675-685

2021

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Incretin-based medications (GLP-1 receptor agonists, DPP-4 inhibitors) as a means to avoid hypoglycaemic episodes

Metabolism, clinical and experimental, 2019-10, Vol.99, p.25-31

2019

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Hepato-incretin function of GLP-1: novel concept and target in type 1 diabetes

Diabetes (New York, N.Y.), 2015-03, Vol.64 (3), p.715-717

Ahrén, Bo

2015

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Avoiding hypoglycemia: a key to success for glucose-lowering therapy in type 2 diabetes

Vascular health and risk management, 2013-01, Vol.9 (default), p.155-163

Ahren, Bo

2013

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Improved glucose regulation in type 2 diabetic patients with DPP-4 inhibitors: focus on alpha and beta cell function and lipid metabolism

Diabetologia, 2016-05, Vol.59 (5), p.907-917

2016

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The Glucose Sensitivity of Insulin Secretion-Lessons from In Vivo and In Vitro Studies in Mice

Biomolecules (Basel, Switzerland), 2022-07, Vol.12 (7), p.976

Ahrén, Bo

2022

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Fasting until noon triggers increased postprandial hyperglycemia and impaired insulin response after lunch and dinner in individuals with type 2 diabetes: a randomized clinical trial

Diabetes care, 2015-10, Vol.38 (10), p.1820-1826

2015

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Incretin, insulinotropic and glucose-lowering effects of whey protein pre-load in type 2 diabetes: a randomised clinical trial

Diabetologia, 2014-09, Vol.57 (9), p.1807-1811

2014

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Efficacy and Safety of Lixisenatide Once-Daily Morning or Evening Injections in Type 2 Diabetes Inadequately Controlled on Metformin (GetGoal-M)

Diabetes care, 2013-09, Vol.36 (9), p.2543-2550

2013

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Glucose‐dependent insulinotropic polypeptide and glucagon‐like peptide‐1 secretion in humans: Characteristics and regulation

Journal of diabetes investigation, 2023-03, Vol.14 (3), p.354-361

2023

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Islet G protein-coupled receptors as potential targets for treatment of type 2 diabetes

Paradigm Shift in the Management of Metabolic Diseases—Next-Generation Incretin Therapy

Glucagon – Early breakthroughs and recent discoveries

DPP-4 Inhibition and the Path to Clinical Proof

Glucagon-like peptide-1 and beta cell glucose sensitivity - a glucose ramp study in mice

GLP-1 for type 2 diabetes

Dipeptidyl peptidase-4 inhibitors: Clinical data and clinical implications

Pleiotropic Mechanisms for the Glucose-Lowering Action of DPP-4 Inhibitors

Gut hormone-based pharmacology: novel formulations and future possibilities for metabolic disease therapy

Glucagon‐like peptide‐1 receptor agonists for type 2 diabetes: A rational drug development

Glucose‐dependent insulinotropic polypeptide secretion after oral macronutrient ingestion: The human literature revisited and a systematic study in model experiments in mice

The dual incretin co-agonist tirzepatide increases both insulin secretion and glucose effectiveness in model experiments in mice

Surrogate measures of insulin sensitivity vs the hyperinsulinaemic–euglycaemic clamp: a meta-analysis

Glucose‐lowering action through targeting islet dysfunction in type 2 diabetes: Focus on dipeptidyl peptidase‐4 inhibition

Creative use of novel glucose-lowering drugs for type 2 diabetes: where will we head in the next 50 years?

Glucose effectiveness: Lessons from studies on insulin‐independent glucose clearance in mice

Incretin-based medications (GLP-1 receptor agonists, DPP-4 inhibitors) as a means to avoid hypoglycaemic episodes

Hepato-incretin function of GLP-1: novel concept and target in type 1 diabetes

Avoiding hypoglycemia: a key to success for glucose-lowering therapy in type 2 diabetes

Improved glucose regulation in type 2 diabetic patients with DPP-4 inhibitors: focus on alpha and beta cell function and lipid metabolism

The Glucose Sensitivity of Insulin Secretion-Lessons from In Vivo and In Vitro Studies in Mice

Fasting until noon triggers increased postprandial hyperglycemia and impaired insulin response after lunch and dinner in individuals with type 2 diabetes: a randomized clinical trial

Incretin, insulinotropic and glucose-lowering effects of whey protein pre-load in type 2 diabetes: a randomised clinical trial

Efficacy and Safety of Lixisenatide Once-Daily Morning or Evening Injections in Type 2 Diabetes Inadequately Controlled on Metformin (GetGoal-M)

Glucose‐dependent insulinotropic polypeptide and glucagon‐like peptide‐1 secretion in humans: Characteristics and regulation

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