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Synaptic Dysfunction in Depression: Potential Therapeutic Targets

Science (American Association for the Advancement of Science), 2012-10, Vol.338 (6103), p.68-72

2012

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Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

Nature medicine, 2016-03, Vol.22 (3), p.238-249

2016

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Neurobiology of the Rapid-Acting Antidepressant Effects of Ketamine: Impact and Opportunities

Biological psychiatry (1969), 2021-07, Vol.90 (2), p.85-95

2021

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Optogenetic stimulation of infralimbic PFC reproduces ketamine’s rapid and sustained antidepressant actions

Proceedings of the National Academy of Sciences - PNAS, 2015-06, Vol.112 (26), p.8106-8111

2015

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Stress blunts serotonin- and hypocretin-evoked EPSCs in prefrontal cortex: Role of corticosterone-mediated apical dendritic atrophy

Proceedings of the National Academy of Sciences - PNAS, 2008-01, Vol.105 (1), p.359-364

2008

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Brain-Derived Neurotrophic Factor Val66Met Allele Impairs Basal and Ketamine-Stimulated Synaptogenesis in Prefrontal Cortex

Biological psychiatry (1969), 2012-06, Vol.71 (11), p.996-1005

2012

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GSK-3 Inhibition Potentiates the Synaptogenic and Antidepressant-Like Effects of Subthreshold Doses of Ketamine

Neuropsychopharmacology (New York, N.Y.), 2013-10, Vol.38 (11), p.2268-2277

2013

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Hypocretins (Orexins) Regulate Serotonin Neurons in the Dorsal Raphe Nucleus by Excitatory Direct and Inhibitory Indirect Actions

The Journal of neuroscience, 2002-11, Vol.22 (21), p.9453-9464

2002

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Nicotine Induces Glutamate Release from Thalamocortical Terminals in Prefrontal Cortex

Neuropsychopharmacology (New York, N.Y.), 2003-02, Vol.28 (2), p.216-225

2003

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Molecular and Cellular Basis of Addiction

Science (American Association for the Advancement of Science), 1997-10, Vol.278 (5335), p.58-63

1997

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Hypocretin (Orexin) Induces Calcium Transients in Single Spines Postsynaptic to Identified Thalamocortical Boutons in Prefrontal Slice

Neuron (Cambridge, Mass.), 2003-09, Vol.40 (1), p.139-150

2003

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Role of cAMP Response Element-Binding Protein in the Rat Locus Ceruleus: Regulation of Neuronal Activity and Opiate Withdrawal Behaviors

The Journal of neuroscience, 2006-04, Vol.26 (17), p.4624-4629

2006

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Hypocretin (orexin) enhances neuron activity and cell synchrony in developing mouse GFP-expressing locus coeruleus

The Journal of physiology, 2002-05, Vol.541 (1), p.169-185

2002

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REDD1 is essential for stress-induced synaptic loss and depressive behavior

Nature medicine, 2014-05, Vol.20 (5), p.531-535

2014

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Modeling “psychosis” in vitro by inducing disordered neuronal network activity in cortical brain slices

Psychopharmacology, 2009-11, Vol.206 (4), p.575-585

Aghajanian, George K.

2009

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The Role of Kv1.2-Containing Potassium Channels in Serotonin-Induced Glutamate Release from Thalamocortical Terminals in Rat Frontal Cortex

The Journal of neuroscience, 2001-12, Vol.21 (24), p.9955-9963

2001

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Medial prefrontal D1 dopamine neurons control food intake

Nature neuroscience, 2014-02, Vol.17 (2), p.248-253

2014

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Ketamine Strengthens CRF-Activated Amygdala Inputs to Basal Dendrites in mPFC Layer V Pyramidal Cells in the Prelimbic but not Infralimbic Subregion, A Key Suppressor of Stress Responses

Neuropsychopharmacology (New York, N.Y.), 2015-08, Vol.40 (9), p.2066-2075

2015

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Neurobiology of Rapid Acting Antidepressants: Role of BDNF and GSK-3β

Neuropsychopharmacology (New York, N.Y.), 2014-01, Vol.39 (1), p.233-233

2014

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Somatodendritic autoreceptor regulation of serotonergic neurons: dependence on l-tryptophan and tryptophan hydroxylase-activating kinases

The European journal of neuroscience, 2005-02, Vol.21 (4), p.945-958

2005

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Brain-Derived Neurotrophic Factor Is Essential for Opiate-Induced Plasticity of Noradrenergic Neurons

The Journal of neuroscience, 2002-05, Vol.22 (10), p.4153-4162

2002

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Torgny Svensson, M.D., Ph.D. (1945–2020)

Neuropsychopharmacology (New York, N.Y.), 2020-10, Vol.45 (11), p.1960-1960

2020

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CREB (cAMP Response Element-Binding Protein) in the Locus Coeruleus: Biochemical, Physiological, and Behavioral Evidence for a Role in Opiate Dependence

The Journal of neuroscience, 1997-10, Vol.17 (20), p.7890-7901

1997

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Regulation of nucleus accumbens activity by the hypothalamic neuropeptide melanin-concentrating hormone

The Journal of neuroscience, 2010-06, Vol.30 (24), p.8263-8273

2010

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Hypocretin and Nicotine Excite the Same Thalamocortical Synapses in Prefrontal Cortex: Correlation with Improved Attention in Rat

The Journal of neuroscience, 2005-05, Vol.25 (21), p.5225-5229

2005

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Synaptic Dysfunction in Depression: Potential Therapeutic Targets

Synaptic plasticity and depression: new insights from stress and rapid-acting antidepressants

Neurobiology of the Rapid-Acting Antidepressant Effects of Ketamine: Impact and Opportunities

Optogenetic stimulation of infralimbic PFC reproduces ketamine’s rapid and sustained antidepressant actions

Stress blunts serotonin- and hypocretin-evoked EPSCs in prefrontal cortex: Role of corticosterone-mediated apical dendritic atrophy

Brain-Derived Neurotrophic Factor Val66Met Allele Impairs Basal and Ketamine-Stimulated Synaptogenesis in Prefrontal Cortex

GSK-3 Inhibition Potentiates the Synaptogenic and Antidepressant-Like Effects of Subthreshold Doses of Ketamine

Hypocretins (Orexins) Regulate Serotonin Neurons in the Dorsal Raphe Nucleus by Excitatory Direct and Inhibitory Indirect Actions

Nicotine Induces Glutamate Release from Thalamocortical Terminals in Prefrontal Cortex

Molecular and Cellular Basis of Addiction

Hypocretin (Orexin) Induces Calcium Transients in Single Spines Postsynaptic to Identified Thalamocortical Boutons in Prefrontal Slice

Role of cAMP Response Element-Binding Protein in the Rat Locus Ceruleus: Regulation of Neuronal Activity and Opiate Withdrawal Behaviors

Hypocretin (orexin) enhances neuron activity and cell synchrony in developing mouse GFP-expressing locus coeruleus

REDD1 is essential for stress-induced synaptic loss and depressive behavior

Modeling “psychosis” in vitro by inducing disordered neuronal network activity in cortical brain slices

The Role of Kv1.2-Containing Potassium Channels in Serotonin-Induced Glutamate Release from Thalamocortical Terminals in Rat Frontal Cortex

Medial prefrontal D1 dopamine neurons control food intake

Ketamine Strengthens CRF-Activated Amygdala Inputs to Basal Dendrites in mPFC Layer V Pyramidal Cells in the Prelimbic but not Infralimbic Subregion, A Key Suppressor of Stress Responses

Neurobiology of Rapid Acting Antidepressants: Role of BDNF and GSK-3β

Somatodendritic autoreceptor regulation of serotonergic neurons: dependence on l-tryptophan and tryptophan hydroxylase-activating kinases

Brain-Derived Neurotrophic Factor Is Essential for Opiate-Induced Plasticity of Noradrenergic Neurons

Torgny Svensson, M.D., Ph.D. (1945–2020)

CREB (cAMP Response Element-Binding Protein) in the Locus Coeruleus: Biochemical, Physiological, and Behavioral Evidence for a Role in Opiate Dependence

Regulation of nucleus accumbens activity by the hypothalamic neuropeptide melanin-concentrating hormone

Hypocretin and Nicotine Excite the Same Thalamocortical Synapses in Prefrontal Cortex: Correlation with Improved Attention in Rat

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