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Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

Gut, 2011-04, Vol.60 (4), p.463-472

2011

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Farnesoid X receptor activation by the novel agonist TC-100 (3α, 7α, 11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid) preserves the intestinal barrier integrity and promotes intestinal microbial reshaping in a mouse model of obstructed bile acid flow

Biomedicine & pharmacotherapy, 2022-09, Vol.153, p.113380-113380, Article 113380

2022

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The FXR agonist obeticholic acid inhibits the cancerogenic potential of human cholangiocarcinoma

PloS one, 2019-01, Vol.14 (1), p.e0210077-e0210077

2019

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Cutting Edge: Selective Usage of Chemokine Receptors by Plasmacytoid Dendritic Cells

The Journal of immunology (1950), 2001-08, Vol.167 (4), p.1862-1866

2001

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Chronic inflammation in the pathogenesis of benign prostatic hyperplasia

International journal of andrology, 2010-06, Vol.33 (3), p.475-488

2010

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Regulatory T cells induced by 1 alpha,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance

The Journal of immunology (1950), 2001-08, Vol.167 (4), p.1945-1953

2001

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Interleukin-12, a key cytokine in Th1-mediated autoimmune diseases

Cellular and molecular life sciences : CMLS, 1999-09, Vol.55 (12), p.1610-1625

Adorini, L

1999

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Therapeutic effects of obeticholic acid (OCA) treatment in a bleomycin-induced pulmonary fibrosis rat model

Journal of endocrinological investigation, 2019-03, Vol.42 (3), p.283-294

2019

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Cardiomyocytes Induce Endothelial Cells to Trans-Differentiate into Cardiac Muscle: Implications for Myocardium Regeneration

Proceedings of the National Academy of Sciences - PNAS, 2001-09, Vol.98 (19), p.10733-10738

2001

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Therapeutic effects of the selective farnesoid X receptor agonist obeticholic acid in a monocrotaline-induced pulmonary hypertension rat model

Journal of endocrinological investigation, 2019-08, Vol.42 (8), p.951-965

2019

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Cytokine‐based immunointervention in the treatment of autoimmune diseases

Clinical and experimental immunology, 2003-05, Vol.132 (2), p.185-192

ADORINI, L.

2003

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Upregulation of MATE-1 transporter by obeticholic acid correlates with increased biliary excretion of asymmetric dimethylarginine during hepatic ischemia/reperfusion injury

Journal of hepatology, 2017, Vol.66 (1), p.S613-S613

2017

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The Farnesoid-X-Receptor Agonist Obeticholic Acid Further Increases Biliary Excretion of Asymmetric Dimethylarginine during Hepatic Ischemia/Reperfusion Injury

Journal of hepatology, 2016, Vol.64 (2), p.S315-S315

2016

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Tolerogenic Dendritic Cells Induced by Vitamin D Receptor Ligands Enhance Regulatory T Cells Inhibiting Autoimmune Diabetes

Annals of the New York Academy of Sciences, 2003-04, Vol.987 (1), p.258-261

ADORINI, LUCIANO

2003

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OC.06.1 ANALYSIS OF THE EFFICACY OF OCA IN PRIMARY BILIARY CIRRHOSIS BY VARYING PATIENT DISEASE SEVERITY ACROSS THREE RANDOMIZED DOUBLE-BLIND, PLACEBO-CONTROLLED CLINICAL TRIALS

Digestive and liver disease, 2016-02, Vol.48, p.e91-e91

2016

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OC.06.8 INTEGRATED ANALYSIS OF EFFICACY OF PHASE II AND III DATA OF OBETICHOLIC ACID IN PBC SUBPOPULATIONS BASED ON AGE AND SEX

Digestive and liver disease, 2016-02, Vol.48, p.e93-e94

2016

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Elevated body mass index correlates with higher seminal plasma interleukin 8 levels and ultrasonographic abnormalities of the prostate in men attending an andrology clinic for infertility

Journal of endocrinological investigation, 2011-11, Vol.34 (10), p.e336-e342

2011

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OC.03.4 EFFICACY AND SAFETY OF OBETICHOLIC ACID IN PATIENTS WITH PRIMARY BILIARY CIRRHOSIS: AN ANALYSIS OF THE ITALIAN PATIENTS FROM A PHASE 3, RANDOMIZED, PLACEBO-CONTROLLED STUDY

Digestive and liver disease, 2016-02, Vol.48, p.e81-e81

2016

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P1155 : FXR Agonism with obeticholic acid may attenuate bone mineral density decrease in subjects with primary biliary cirrhosis

Journal of hepatology, 2015-04, Vol.62, p.S786-S786

2015

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Increase in transporter MATE-1 expression induced by obeticholic acid correlates with higher biliary excretion of asymmetric dimethylarginine during hepatic ischemia/reperfusion injury

Digestive and liver disease, 2017-02, Vol.49 (1), p.e30-e30

2017

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Elocalcitol Inhibits Inflammatory Responses in Human Thyroid Cells and T Cells

Endocrinology (Philadelphia), 2008-07, Vol.149 (7), p.3626-3634

2008

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Metabolic Profile of Obeticholic Acid and Endogenous Bile Acids in Rats with Decompensated Liver Cirrhosis

Clinical and translational science, 2017-07, Vol.10 (4), p.292-301

2017

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Interleukin 12 and autoimmune diabetes

Nature genetics, 2001-02, Vol.27 (2), p.131-132

Adorini, Luciano

2001

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Vitamin D receptor agonists inhibit pro-inflammatory cytokine production from the respiratory epithelium in cystic fibrosis

Journal of cystic fibrosis, 2011-12, Vol.10 (6), p.428-434

2011

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OC.12.8 LONG-TERM SAFETY OF OBETICHOLIC ACID IN PATIENTS WITH PRIMARY BILIARY CIRRHOSIS

Digestive and liver disease, 2016-02, Vol.48, p.e117-e118

2016

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Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease

Farnesoid X receptor activation by the novel agonist TC-100 (3α, 7α, 11β-Trihydroxy-6α-ethyl-5β-cholan-24-oic Acid) preserves the intestinal barrier integrity and promotes intestinal microbial reshaping in a mouse model of obstructed bile acid flow

The FXR agonist obeticholic acid inhibits the cancerogenic potential of human cholangiocarcinoma

Cutting Edge: Selective Usage of Chemokine Receptors by Plasmacytoid Dendritic Cells

Chronic inflammation in the pathogenesis of benign prostatic hyperplasia

Regulatory T cells induced by 1 alpha,25-dihydroxyvitamin D3 and mycophenolate mofetil treatment mediate transplantation tolerance

Interleukin-12, a key cytokine in Th1-mediated autoimmune diseases

Therapeutic effects of obeticholic acid (OCA) treatment in a bleomycin-induced pulmonary fibrosis rat model

Cardiomyocytes Induce Endothelial Cells to Trans-Differentiate into Cardiac Muscle: Implications for Myocardium Regeneration

Therapeutic effects of the selective farnesoid X receptor agonist obeticholic acid in a monocrotaline-induced pulmonary hypertension rat model

Cytokine‐based immunointervention in the treatment of autoimmune diseases

Upregulation of MATE-1 transporter by obeticholic acid correlates with increased biliary excretion of asymmetric dimethylarginine during hepatic ischemia/reperfusion injury

The Farnesoid-X-Receptor Agonist Obeticholic Acid Further Increases Biliary Excretion of Asymmetric Dimethylarginine during Hepatic Ischemia/Reperfusion Injury

Tolerogenic Dendritic Cells Induced by Vitamin D Receptor Ligands Enhance Regulatory T Cells Inhibiting Autoimmune Diabetes

OC.06.1 ANALYSIS OF THE EFFICACY OF OCA IN PRIMARY BILIARY CIRRHOSIS BY VARYING PATIENT DISEASE SEVERITY ACROSS THREE RANDOMIZED DOUBLE-BLIND, PLACEBO-CONTROLLED CLINICAL TRIALS

OC.06.8 INTEGRATED ANALYSIS OF EFFICACY OF PHASE II AND III DATA OF OBETICHOLIC ACID IN PBC SUBPOPULATIONS BASED ON AGE AND SEX

Elevated body mass index correlates with higher seminal plasma interleukin 8 levels and ultrasonographic abnormalities of the prostate in men attending an andrology clinic for infertility

OC.03.4 EFFICACY AND SAFETY OF OBETICHOLIC ACID IN PATIENTS WITH PRIMARY BILIARY CIRRHOSIS: AN ANALYSIS OF THE ITALIAN PATIENTS FROM A PHASE 3, RANDOMIZED, PLACEBO-CONTROLLED STUDY

P1155 : FXR Agonism with obeticholic acid may attenuate bone mineral density decrease in subjects with primary biliary cirrhosis

Increase in transporter MATE-1 expression induced by obeticholic acid correlates with higher biliary excretion of asymmetric dimethylarginine during hepatic ischemia/reperfusion injury

Elocalcitol Inhibits Inflammatory Responses in Human Thyroid Cells and T Cells

Metabolic Profile of Obeticholic Acid and Endogenous Bile Acids in Rats with Decompensated Liver Cirrhosis

Interleukin 12 and autoimmune diabetes

Vitamin D receptor agonists inhibit pro-inflammatory cytokine production from the respiratory epithelium in cystic fibrosis

OC.12.8 LONG-TERM SAFETY OF OBETICHOLIC ACID IN PATIENTS WITH PRIMARY BILIARY CIRRHOSIS

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