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Chemosensitization of tumors via simultaneous delivery of STAT3 inhibitor and doxorubicin through HPMA copolymer-based nanotherapeutics with pH-sensitive activation

Nanomedicine, 2024-02, Vol.56, p.102730-102730, Article 102730

2024

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Synthesis of Well-Defined Semitelechelic Poly[N‑(2-hydroxypropyl)methacrylamide] Polymers with Functional Group at the α‑End of the Polymer Chain by RAFT Polymerization

Macromolecules, 2013-03, Vol.46 (6), p.2100-2108

2013

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Nanotherapeutics shielded with a pH responsive polymeric layer

Physiological research, 2015-01, Vol.64 (Suppl 1), p.S29-S44

2015

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Micelle-forming HPMA copolymer conjugates of ritonavir bound via a pH-sensitive spacer with improved cellular uptake designed for enhanced tumor accumulation

Journal of materials chemistry. B, Materials for biology and medicine, 2016-12, Vol.4 (47), p.762-7629

2016

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Synthesis and properties of new N-(2-hydroxypropyl)methacrylamide copolymers containing thiazolidine-2-thione reactive groups

Reactive & functional polymers, 2006-12, Vol.66 (12), p.1525-1538

2006

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Synthesis of Poly[N‑(2-hydroxypropyl)methacrylamide] Conjugates of Inhibitors of the ABC Transporter That Overcome Multidrug Resistance in Doxorubicin-Resistant P388 Cells in Vitro

Biomacromolecules, 2014-08, Vol.15 (8), p.3030-3043

2014

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Differences in the intracellular fate of free and polymer-bound doxorubicin

Journal of controlled release, 2002-04, Vol.80 (1-3), p.101-117

2002

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Polymeric drugs based on conjugates of synthetic and natural macromolecules: I. Synthesis and physico-chemical characterisation

Journal of controlled release, 2000-02, Vol.64 (1), p.63-79

2000

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Image-guided and passively tumour-targeted polymeric nanomedicines for radiochemotherapy

British journal of cancer, 2008-09, Vol.99 (6), p.900-910

2008

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Doxorubicin release is not a prerequisite for the in vitro cytotoxicity of HPMA-based pharmaceuticals: In vitro effect of extra drug-free GlyPheLeuGly sequences

Journal of controlled release, 2008-04, Vol.127 (2), p.110-120

2008

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Thermoresponsive polymers as promising new materials for local radiotherapy

Applied radiation and isotopes, 2005-10, Vol.63 (4), p.423-431

2005

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Behavior of Surface-Anchored Poly(acrylic acid) Brushes with Grafting Density Gradients on Solid Substrates: 1. Experiment

Macromolecules, 2007-11, Vol.40 (24), p.8756-8764

2007

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Polymeric drugs based on conjugates of synthetic and natural macromolecules.: II. Anti-cancer activity of antibody or (Fab′) 2-targeted conjugates and combined therapy with immunomodulators

Journal of controlled release, 2000-02, Vol.64 (1), p.241-261

2000

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HPMA copolymers containing doxorubicin bound by a proteolytically or hydrolytically cleavable bond: comparison of biological properties in vitro

Journal of controlled release, 2004-09, Vol.99 (2), p.301-314

2004

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Identification of Protein Targets of Bioactive Small Molecules Using Randomly Photomodified Probes

ACS chemical biology, 2018-12, Vol.13 (12), p.3333-3342

2018

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Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers

Biomaterials, 2009-07, Vol.30 (20), p.3466-3475

2009

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A versatile system for receptor-mediated gene delivery permits increased entry of DNA into target cells, enhanced delivery to the nucleus and elevated rates of transgene expression

Gene therapy, 2000-08, Vol.7 (15), p.1337-1343

2000

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Poly[ N-(2-hydroxypropyl)methacrylamide] Polymers Diffuse in Brain Extracellular Space with Same Tortuosity as Small Molecules

Biophysical journal, 2001, Vol.80 (1), p.542-548

2001

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Poly[N-(2-hydroxypropyl)methacrylamide] conjugates of methotrexate

Journal of controlled release, 1997-12, Vol.49 (2-3), p.123-132

1997

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Targeting of human and mouse T-lymphocytes by monoclonal antibody-HPMA copolymer–doxorubicin conjugates directed against different T-cell surface antigens

Journal of controlled release, 1998-03, Vol.52 (3), p.253-270

1998

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Reactive polymers for modification of biologically active molecules and gene delivery vectors

Journal of controlled release, 2006-11, Vol.116 (2), p.e3-e5

2006

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POLY(HPMA)-COATED LIPOSOMES DEMONSTRATE PROLONGED CIRCULATION IN MICE

Journal of liposome research, 2001-01, Vol.11 (2-3), p.153-164

2001

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Formation and Properties of Anchored Polymers with a Gradual Variation of Grafting Densities on Flat Substrates

Macromolecules, 2003-04, Vol.36 (7), p.2448-2453

2003

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Multifunctional Cytotoxic Stealth Nanoparticles. A Model Approach with Potential for Cancer Therapy

Nano letters, 2009-02, Vol.9 (2), p.636-642

2009

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Induction of Systemic Antitumour Resistance with Targeted Polymers

Scandinavian journal of immunology, 2005-07, Vol.62 (s1), p.100-105

2005

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Chemosensitization of tumors via simultaneous delivery of STAT3 inhibitor and doxorubicin through HPMA copolymer-based nanotherapeutics with pH-sensitive activation

Synthesis of Well-Defined Semitelechelic Poly[N‑(2-hydroxypropyl)methacrylamide] Polymers with Functional Group at the α‑End of the Polymer Chain by RAFT Polymerization

Nanotherapeutics shielded with a pH responsive polymeric layer

Micelle-forming HPMA copolymer conjugates of ritonavir bound via a pH-sensitive spacer with improved cellular uptake designed for enhanced tumor accumulation

Synthesis and properties of new N-(2-hydroxypropyl)methacrylamide copolymers containing thiazolidine-2-thione reactive groups

Synthesis of Poly[N‑(2-hydroxypropyl)methacrylamide] Conjugates of Inhibitors of the ABC Transporter That Overcome Multidrug Resistance in Doxorubicin-Resistant P388 Cells in Vitro

Differences in the intracellular fate of free and polymer-bound doxorubicin

Polymeric drugs based on conjugates of synthetic and natural macromolecules: I. Synthesis and physico-chemical characterisation

Image-guided and passively tumour-targeted polymeric nanomedicines for radiochemotherapy

Doxorubicin release is not a prerequisite for the in vitro cytotoxicity of HPMA-based pharmaceuticals: In vitro effect of extra drug-free GlyPheLeuGly sequences

Thermoresponsive polymers as promising new materials for local radiotherapy

Behavior of Surface-Anchored Poly(acrylic acid) Brushes with Grafting Density Gradients on Solid Substrates: 1. Experiment

Polymeric drugs based on conjugates of synthetic and natural macromolecules.: II. Anti-cancer activity of antibody or (Fab′) 2-targeted conjugates and combined therapy with immunomodulators

HPMA copolymers containing doxorubicin bound by a proteolytically or hydrolytically cleavable bond: comparison of biological properties in vitro

Identification of Protein Targets of Bioactive Small Molecules Using Randomly Photomodified Probes

Simultaneous delivery of doxorubicin and gemcitabine to tumors in vivo using prototypic polymeric drug carriers

A versatile system for receptor-mediated gene delivery permits increased entry of DNA into target cells, enhanced delivery to the nucleus and elevated rates of transgene expression

Poly[ N-(2-hydroxypropyl)methacrylamide] Polymers Diffuse in Brain Extracellular Space with Same Tortuosity as Small Molecules

Poly[N-(2-hydroxypropyl)methacrylamide] conjugates of methotrexate

Targeting of human and mouse T-lymphocytes by monoclonal antibody-HPMA copolymer–doxorubicin conjugates directed against different T-cell surface antigens

Reactive polymers for modification of biologically active molecules and gene delivery vectors

POLY(HPMA)-COATED LIPOSOMES DEMONSTRATE PROLONGED CIRCULATION IN MICE

Formation and Properties of Anchored Polymers with a Gradual Variation of Grafting Densities on Flat Substrates

Multifunctional Cytotoxic Stealth Nanoparticles. A Model Approach with Potential for Cancer Therapy

Induction of Systemic Antitumour Resistance with Targeted Polymers

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