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Genome-wide census of ATF4 binding sites and functional profiling of trait-associated genetic variants overlapping ATF4 binding motifs

PLoS genetics, 2023-10, Vol.19 (10), p.e1011014-e1011014

2023

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A human-specific VNTR in the TRIB3 promoter causes gene expression variation between individuals

PLoS genetics, 2020-08, Vol.16 (8), p.e1008981-e1008981

2020

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The transcription factor CHOP, an effector of the integrated stress response, is required for host sensitivity to the fungal intracellular pathogen Histoplasma capsulatum

PLoS pathogens, 2017-09, Vol.13 (9), p.e1006589

2017

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TRIB3 enhances cell viability during glucose deprivation in HEK293-derived cells by upregulating IGFBP2, a novel nutrient deficiency survival factor

Biochimica et biophysica acta, 2015-10, Vol.1853 (10), p.2492-2505

2015

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Elevated ATF4 Expression, in the Absence of Other Signals, Is Sufficient for Transcriptional Induction via CCAAT Enhancer-binding Protein-activating Transcription Factor Response Elements

The Journal of biological chemistry, 2009-08, Vol.284 (32), p.21241-21248

2009

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Trib3 is developmentally and nutritionally regulated in the brain but is dispensable for spatial memory, fear conditioning and sensing of amino acid-imbalanced diet

PloS one, 2014-04, Vol.9 (4), p.e94691

2014

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Amino acid availability controls TRB3 transcription in liver through the GCN2/eIF2α/ATF4 pathway

PloS one, 2010-12, Vol.5 (12), p.e15716-e15716

2010

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Evidence for a role of TRIB3 in the regulation of megakaryocytopoiesis

Scientific reports, 2017-07, Vol.7 (1), p.6684-9, Article 6684

2017

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Trib3 is regulated by IL-3 and affects bone marrow-derived mast cell survival and function

Cellular immunology, 2012-11, Vol.280 (1), p.68-75

2012

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Human TRB3 is upregulated in stressed cells by the induction of translationally efficient mRNA containing a truncated 5′-UTR

Gene, 2009-09, Vol.444 (1), p.24-32

2009

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Characterization of human NIPK ( TRB3, SKIP3) gene activation in stressful conditions

Biochemical and biophysical research communications, 2005-04, Vol.330 (1), p.210-218

2005

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TRB3 protects cells against the growth inhibitory and cytotoxic effect of ATF4

Experimental cell research, 2007-10, Vol.313 (16), p.3556-3567

2007

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Bcl-2 Inhibition of Neural Death: Decreased Generation of Reactive Oxygen Species

Science (American Association for the Advancement of Science), 1993-11, Vol.262 (5137), p.1274-1277

1993

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The C/ebp-Atf response element (CARE) location reveals two distinct Atf4-dependent, elongation-mediated mechanisms for transcriptional induction of aminoacyl-tRNA synthetase genes in response to amino acid limitation

Nucleic acids research, 2016-07, Vol.44 (20), p.9719

2016

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Pharmacological or TRIB3-Mediated Suppression of ATF4 Transcriptional Activity Promotes Hepatoma Cell Resistance to Proteasome Inhibitor Bortezomib

Cancers, 2021-05, Vol.13 (10), p.2341

2021

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Mammalian Pseudokinase TRIB3 in Normal Physiology and Disease: Charting the Progress in Old and New Avenues

Current protein & peptide science, 2017-08, Vol.18 (8), p.819

2017

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Mouse NIPK interacts with ATF4 and affects its transcriptional activity

Experimental cell research, 2003-06, Vol.286 (2), p.308-320

2003

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TRIB3 increases cell resistance to arsenite toxicity by limiting the expression of the glutathione-degrading enzyme CHAC1

Biochimica et biophysica acta, 2016-11, Vol.1863 (11), p.2668-2680

2016

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TRIB3 limits FGF21 induction during in vitro and in vivo nutrient deficiencies by inhibiting C/EBP–ATF response elements in the Fgf21 promoter

Biochimica et biophysica acta. Gene regulatory mechanisms, 2018-03, Vol.1861 (3), p.271-281

2018

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Bcl-2 Expression in Neural Cells Blocks Activation of ICE/CED-3 Family Proteases during Apoptosis

The Journal of neuroscience, 1996-09, Vol.16 (18), p.5654-5660

1996

Volltextzugriff (PDF)

Amino Acid Availability Controls TRB3 Transcription in Liver through the GCN2/eIF2[alpha]/ATF4 Pathway

PloS one, 2010-12, Vol.5 (12), p.e15716

2010

Volltextzugriff (PDF)

Comparative expression analysis of the genes encoding polypyrimidine tract binding protein (PTB) and its neural homologue (brPTB) in prenatal and postnatal mouse brain

Mechanisms of development, 2001-03, Vol.101 (1), p.217-220

2001

Volltextzugriff (PDF)

CD244 Marks Non-Functional Hematopoietic Stem Cells with a Mast Cell Signature after Induction of Endoplasmic Reticulum Stress

Blood, 2019-11, Vol.134 (Supplement_1), p.2474-2474

2019

Volltextzugriff (PDF)

Cleavage of Actin by Interleukin 1β -Converting Enzyme to Reverse DNase I Inhibition

Proceedings of the National Academy of Sciences - PNAS, 1996-03, Vol.93 (5), p.2234-2238

1996

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Activation of CPP32 during apoptosis of neurons and astrocytes

Journal of neuroscience research, 1997-04, Vol.48 (2), p.168-180

1997

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Genome-wide census of ATF4 binding sites and functional profiling of trait-associated genetic variants overlapping ATF4 binding motifs

A human-specific VNTR in the TRIB3 promoter causes gene expression variation between individuals

The transcription factor CHOP, an effector of the integrated stress response, is required for host sensitivity to the fungal intracellular pathogen Histoplasma capsulatum

TRIB3 enhances cell viability during glucose deprivation in HEK293-derived cells by upregulating IGFBP2, a novel nutrient deficiency survival factor

Elevated ATF4 Expression, in the Absence of Other Signals, Is Sufficient for Transcriptional Induction via CCAAT Enhancer-binding Protein-activating Transcription Factor Response Elements

Trib3 is developmentally and nutritionally regulated in the brain but is dispensable for spatial memory, fear conditioning and sensing of amino acid-imbalanced diet

Amino acid availability controls TRB3 transcription in liver through the GCN2/eIF2α/ATF4 pathway

Evidence for a role of TRIB3 in the regulation of megakaryocytopoiesis

Trib3 is regulated by IL-3 and affects bone marrow-derived mast cell survival and function

Human TRB3 is upregulated in stressed cells by the induction of translationally efficient mRNA containing a truncated 5′-UTR

Characterization of human NIPK ( TRB3, SKIP3) gene activation in stressful conditions

TRB3 protects cells against the growth inhibitory and cytotoxic effect of ATF4

Bcl-2 Inhibition of Neural Death: Decreased Generation of Reactive Oxygen Species

The C/ebp-Atf response element (CARE) location reveals two distinct Atf4-dependent, elongation-mediated mechanisms for transcriptional induction of aminoacyl-tRNA synthetase genes in response to amino acid limitation

Pharmacological or TRIB3-Mediated Suppression of ATF4 Transcriptional Activity Promotes Hepatoma Cell Resistance to Proteasome Inhibitor Bortezomib

Mammalian Pseudokinase TRIB3 in Normal Physiology and Disease: Charting the Progress in Old and New Avenues

Mouse NIPK interacts with ATF4 and affects its transcriptional activity

TRIB3 increases cell resistance to arsenite toxicity by limiting the expression of the glutathione-degrading enzyme CHAC1

TRIB3 limits FGF21 induction during in vitro and in vivo nutrient deficiencies by inhibiting C/EBP–ATF response elements in the Fgf21 promoter

Bcl-2 Expression in Neural Cells Blocks Activation of ICE/CED-3 Family Proteases during Apoptosis

Amino Acid Availability Controls TRB3 Transcription in Liver through the GCN2/eIF2[alpha]/ATF4 Pathway

Comparative expression analysis of the genes encoding polypyrimidine tract binding protein (PTB) and its neural homologue (brPTB) in prenatal and postnatal mouse brain

CD244 Marks Non-Functional Hematopoietic Stem Cells with a Mast Cell Signature after Induction of Endoplasmic Reticulum Stress

Cleavage of Actin by Interleukin 1β -Converting Enzyme to Reverse DNase I Inhibition

Activation of CPP32 during apoptosis of neurons and astrocytes

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